siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
FUT3 alpha3/4 Fucosyltransferase 3-Dependent Synthesis of Sialyl Lewis A on CD44 Variant Containing Exon 6 Mediates Polymorphonuclear Leukocyte Detachment from Intestinal Epithelium during Transepithelial Migration J Immunol. 2013 Nov 1;191(9):4804-17, 2013 Nov siRNA SR301673
FXN Acute frataxin knockdown in induced pluripotent stem cell-derived cardiomyocytes activates a type I interferon response Disease Models & Mechanisms, 2023 May siRNA SR320201
FXN Ferroptosis as a novel therapeutic target for Friedreich's ataxia J. Pharmacol. Exp. Ther., 2019 Jan siRNA SR320201
FXN Identification of p38 MAPK as a novel therapeutic target for Friedreich's ataxia Sci Rep, 2018 Mar siRNA SR405405
FYB1 The adapter proteins ADAP and Nck cooperate in T cell adhesion Mol. Immunol. 72-79 60 1. April 2014, 2014 Apr siRNA SR301681
FZD1 Wnt pathway in atypical teratoid rhabdoid tumors Neuro-oncology, 2014 Sep siRNA SR305440
FZD4 MicroRNA-101 inhibits cell migration and invasion in bladder cancer via targeting FZD4 Exp Ther Med, 2019 Feb SiRNA SR305441
FZD7 Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma Cell Death Dis, 2018 Aug siRNA SR305443
Fzd7 Frizzled Gene Expression and Negative Regulation of Canonical WNT-ß?-catenin Signaling in Mouse F9 Teratocarcinoma Cells Biochemistry and Cell Biology, 2016 Sep siRNA SR417570
FZR1 USP22 deubiquitinates CD274 to suppress anti-cancer immunity Cancer Immunol Res, 2019 Aug siRNA SR324108
G3BP1 A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer iScience, 2020 Aug siRNA SR306845
G3BP1 N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis Nat. Struct. Mol. Biol., 2017 Oct siRNA SR306845
G6PD Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells Redox Biol, 2018 Apr siRNA SR301686
G6pdx G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea J. Neurosci., 2017 Jun siRNA SR416484
GAB1 Macrophage Stimulating Protein (MSP) Preserves Blood Brain Barrier Integrity After Intracerebral Hemorrhage Through RON Dependent GAB1/Src/β-catenin Pathway Activation in a Mouse Model J. Neurochem., 2018 Oct siRNA SR419225
GABPA Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-NMDA receptor coupling J Biol Chem. 2013 Oct 17, 2013 Oct siRNA SR301693
GALNT3 Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells BMC Cancer, 2018 Nov siRNA SR301729
GALR1 Coordinated Targeting of Galanin Receptors on Cholangiocytes and Hepatic Stellate Cells Ameliorates Liver Fibrosis in Multidrug Resistance Protein 2 Knockout Mice Am. J. Pathol., 2020 Jan siRNA SR411760
GAPDH Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition Cell, 2014 Oct siRNA SR301734
GAPDH Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease Kidney Int., Jan 2014., 2014 Jan siRNA SR301734
GARS HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease Brain, 2018 Feb siRNA SR419603
GATA3 MiR-205 Promotes the Viability, Migration, and Tube Formation of Cervical Cancer Cells In Vitro by Targeting GATA3 Cancer biotherapy & radiopharmaceuticals, 2021 Mar siRNA SR320264
GATA3 Differential expression and function of the endogenous lactate receptor, GPR81, in ER��-positive/HER2-positive epithelial vs. post-EMT triple-negative mesenchymal breast cancer cells JCMT, 2019 Jun siRNA SR320264
GATA3 TOX expression and role in CTCL J Eur Acad Dermatol Venereol, 2016 Sep siRNA SR320264
GATA4 The zinc finger protein GATA4 induces MET and cellular senescence through the NF-κB pathway in hepatocellular carcinoma J. Gastroenterol. Hepatol., 2019 Apr siRNA SR301745
GBA Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease Kidney Int., Jan 2014., 2014 Jan siRNA SR301748
GCGR The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice Mol Metab, 2019 Feb siRNA SR415672
GCLC Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis Carcinogenesis, 2018 Jan siRNA SR301815
GCLC Inhibition of glutathione production induces macrophage CD36 expression and enhances cellular oxLDL uptake J. Biol. Chem., 2015 Jul siRNA SR301815
GCNT1 Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Oncotarget, 2020 Dec siRNA SR320274
GCNT1 Aberrant O-glycosylation modulates aggressiveness in neuroblastoma Oncotarget, 2018 Sep siRNA SR301767
GDF11 Reduced expression of growth differentiation factor 11 promoted the progression of chronic obstructive pulmonary disease by activating the AKT signaling pathway Biomed. Pharmacother., 2018 Apr siRNA SR413495
GDF15 Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion Oncogene, 2019 Feb siRNA SR408860
GDF9 Insulin-like 3 induced rat preantral follicular growth is mediated by growth differentiation factor 9 Endocrinology. 2013 Oct 29., 2013 Oct siRNA SR505007
GDNF Decreased DNA methylation in the promoter region of the WNT5A and GDNF genes may promote the osteogenicity of mesenchymal stem cells from patients with ossified spinal ligaments J. Pharmacol. Sci., 2015 Apr siRNA SR301778
GEMIN4 Gemin4 functions as a coregulator of the mineralocorticoid receptor J. Mol. Endocrinol., 2015 Jan siRNA SR309405
GFRA1 Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action Proc. Natl. Acad. Sci. U.S.A., 2020 Aug siRNA SR415185
GFUS Oncogenic potential of TSTA3 in breast cancer and its regulation by the tumor suppressors miR-125a-5p and miR-125b Tumour Biol., 2015 Nov siRNA SR304956
GHR Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo Cancers, 2020 Dec siRNA SR301794
GHR Growth Hormone Upregulates Melanocyte-Inducing Transcription Factor Expression and Activity via JAK2-STAT5 and SRC Signaling in GH Receptor-Positive Human Melanoma Cancers (Basel) 2019, 2019 Sep siRNA SR301794
GHR TITLE: Growth hormone receptor (GHR) knockdown sensitizes human melanoma cells to chemotherapy by attenuating expression of ABC drug efflux pumps researchgate.net, 2017 May siRNA SR301794
GHR Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways Oncotarget, 2017 Mar siRNA SR301794
GIPR Physiological roles of the GIP receptor in murine brown adipose tissue Mol Metab, 2019 Aug siRNA SR406328
GIPR TCF1 links GIPR signaling to the control of beta cell function and survival Nat. Med., 2015 Dec siRNA SR406328
GJA1 Interferon-γ and high glucose-induced opening of Cx43 hemichannels causes endothelial cell dysfunction and damage Biochim Biophys Acta Mol Cell Res, 2020 Apr siRNA SR320291
GJA1 Connexin 43 hemichannels and pannexin-1 channels contribute to the α-synuclein-induced dysfunction and death of astrocytes Glia, 2019 Apr siRNA SR412884
GJA1 Connexin 43 Hemichannel Activity Promoted by Pro-Inflammatory Cytokines and High Glucose Alters Endothelial Cell Function Front Immunol, 2018 Aug siRNA SR412884
Gja1 Cannabinoids prevent the amyloid ß-induced activation of astroglial hemichannels: A neuroprotective mechanism Glia, 2016 Oct siRNA SR412884
GJA1 Prenatal exposure to inflammatory conditions increases Cx43 and Panx1 unopposed channel opening and activation of astrocytes in the offspring effect on neuronal survival Glia, 2015 Jun siRNA SR412884
GJA1 Astrocytes inhibit nitric oxide-dependent Ca(2+) dynamics in activated microglia: Involvement of ATP released via pannexin 1 channels Glia. 2013 Dec;61(12):2023-37, 2013 Oct siRNA SR512943