siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
GJB6 HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS J Neuroinflammation, 2016 Mar siRNA SR307369
GLA Drug delivery using polyhistidine peptide-modified liposomes that target endogenous lysosome Biochem. Biophys. Res. Commun., 2018 Jun siRNA SR320297
GLA Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease Kidney Int., Jan 2014., 2014 Jan siRNA SR301812
GLI1 Driver mutations in USP8 wild type Cushing's disease Neuro-oncology, 2019 Jun siRNA SR421553
GLI1 Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells Cell Death Dis, Jan 2014., 2014 Jan siRNA SR301820
GLI2 Placental sonic hedgehog pathway regulates foetal growth via insulin-like growth factor axis in preeclampsia. The Journal of clinical endocrinology and metabolism, 2019 May siRNA SR301821
GLP1R Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats Neuropharmacology, 2017 Oct siRNA SR415041
GLP1R TCF1 links GIPR signaling to the control of beta cell function and survival Nat. Med., 2015 Dec siRNA SR415041
GLP1R Metformin ameliorates lipotoxicity-induced mesangial cell apoptosis partly via upregulation of Glucagon like peptide-1 receptor (GLP-1R) Arch. Biochem. Biophys., 2015 Aug siRNA SR510491
Gls Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling. American journal of physiology. Heart and circulatory physiology, 2022 May siRNA SR500238
GLS MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer Mol. Cancer, 2014 Oct siRNA SR301829
GNA11 A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin-biased signaling Sci Signal, 2018 Feb siRNA SR301839
GNA11 Allosteric Modulation of the Calcium-Sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein alpha-11 Mutations causing Hypercalcemic and Hypocalcemic Disorders J. Biol. Chem., 2016 Mar siRNA SR301839
GNAT3 Activation of the sweet taste receptor, T1R3, by the artificial sweetener sucralose regulates the pulmonary endothelium Am. J. Physiol. Lung Cell Mol. Physiol., 2017 Sep siRNA SR411970
GPBAR1 TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of Caspase-8/NLRP3 after middle cerebral artery occlusion in rats Research Square, 2020 Dec siRNA SR315770
GPBAR1 Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats J. Biomed. Sci., 2020 May siRNA SR510164
Gpbar1 TGR5 suppresses high glucose-induced upregulation of fibronectin and transforming growth factor-ß1 in rat glomerular mesangial cells by inhibiting RhoA/ROCK signaling Endocrine, 2016 Jul siRNA SR510164
GPER1 The GPER1/SPOP axis mediates ubiquitination-dependent degradation of ERα to inhibit the growth of breast cancer induced by oestrogen Cancer Lett, 2020 Oct siRNA SR320365
GPER1 GPER1 promotes estrogen receptor negative breast cancer cell migration and invasion via non-genomic activation of c-Src/NF-κB/focal adhesion kinase cascade Journal of Bio-X Research, 2018 Sep siRNA SR301912
Gper1 The activation of the G protein-coupled estrogen receptor (GPER) inhibits the proliferation of mouse melanoma K1735-M2 cells. Chemico-biological interactions, 2017 Nov siRNA SR412671
Gper1 Estrogen stimulated migration and invasion of estrogen receptor-negative breast cancer cells involves an ezrin-dependent crosstalk between G protein-coupled receptor 30 and estrogen receptor beta signaling. Steroids, 2017 Jul siRNA SR412671
GPNMB Single-walled carbon-nanohorns improve biocompatibility over nanotubes by triggering less protein-initiated pyroptosis and apoptosis in macrophages Nat Commun, 2018 Jun siRNA SR417607
GPR151 Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology Nat Commun, 2019 Sep siRNA SR413989
GPRC5B The orphan receptor GPRC5B modulates inflammatory and fibrotic pathways in cardiac fibroblasts and mice hearts Biochem. Biophys. Res. Commun., 2019 May siRNA SR507482
GPX1 Expression of glutathione peroxidase 1 in the spheno-occipital synchondrosis and its role in ROS-induced apoptosis Eur J Orthod, 2014 Oct siRNA SR405153
GRIK2 GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis Oncotarget, 2017 Apr siRNA SR301950
GSC Bone Morphogenetic Protein-10 induces cardiomyocyte proliferation and improves cardiac function after myocardial infarction J. Cell. Biochem., 2014 Jun siRNA SR315497
GSDMD Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis Cell Death Dis, 2019 Jun siRNA SR415714
Gsk3b GSK-3ß/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy PLoS ONE, 2016 Dec siRNA SR506287
GSR Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis Carcinogenesis, 2018 Jan siRNA SR301982
GSTCD Defining a role for lung function associated gene GSTCD in cell homeostasis Respir. Res., 2019 Aug siRNA SR312613
GSTM1 Autophagy activation contributes to glutathione transferase Mu 1-mediated chemoresistance in hepatocellular carcinoma Oncol Lett, 2018 Jul siRNA SR301988
GSTM1 Autophagy activation contributes to glutathione transferase Mu 1‑mediated chemoresistance in hepatocellular carcinoma Oncol Lett, 2018 May siRNA SR301988
GSTO1 Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor Nat Commun, 2016 Oct siRNA SR306263
GTF2IRD1 Autophagy inhibition blunts PDGFRA adipose progenitors\' cell-autonomous fibrogenic response to high-fat diet Autophagy, 2020 Jan siRNA SR421858
GUK1 Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer Nature communications, 2021 Feb siRNA SR501698
H1-2 Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-Induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells J. Biol. Chem, 2016 Dec siRNA SR302039
H19 The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b. Science signaling, 2018 Apr siRNA SR402967
H19 MiR-675-5p supports hypoxia induced epithelial to mesenchymal transition in colon cancer cells Oncotarget, 2017 Apr siRNA SR319206
H19 CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA Mol. Cancer, 2015 Aug siRNA SR319206
H2AZ1 H2A.Z regulates tumorigenesis, metastasis and sensitivity to cisplatin in intrahepatic cholangiocarcinoma Int. J. Oncol., 2018 Apr siRNA SR302047
HADHA Association of HADHA with human RNA silencing machinery Biochem. Biophys. Res. Commun., 2015 Sep siRNA SR302056
HAVCR2 Hepatitis A virus cellular receptor 2 (HAVCR2) is decreased with viral infection and regulates pro-labour mediators OA Am. J. Reprod. Immunol., 2017 May siRNA SR313697
Hbegf ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion JCI Insight, 2022 Sep siRNA SR405442
HBP1 HBP1 promoter methylation augments the oncogenic ß-catenin to correlate with prognosis in NSCLC J. Cell. Mol. Med., 2014 Jun siRNA SR308913
HCAR2 Butyrate attenuates lipolysis in adipocytes co-cultured with macrophages through non-prostaglandin E2-mediated and prostaglandin E2-mediated pathways Lipids Health Dis, 2016 Dec siRNA SR412150
Hcar2 Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson¿s disease models are mediated by GPR109A-dependent mechanisms J Neuroinflammation, 2015 Jan siRNA SR509630
HCAR3 Metabolites of lactic acid bacteria present in fermented foods are highly potent agonists of human hydroxycarboxylic acid receptor 3 PLoS Genet., 2019 May siRNA SR305839
Hcfc1 Insulin receptor associates with promoters genome-wide and regulates gene expression Cell, 2020 Apr siRNA SR423371
HCFC1 Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression Cell, 2019 Apr siRNA SR302076