shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Fundc1 A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy Redox Biology, 2021 Nov shRNA TR702819
FURIN Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF / MEK signaling Molecular Oncology, 2023 Feb shRNA TR312903
FURIN Human α-L-fucosidase-1 attenuates the invasive properties of thyroid cancer Oncotarget, 2017 Apr shRNA TG312903
Furin Furin Is the Major Proprotein Convertase Required for KISS1-to-Kisspeptin Processing PLoS ONE, Jan 2014., 2014 Jan shRNA TF312903
FUT4 Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis J. Neurooncol., 2019 May shRNA TG312897
FUT7 Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis J. Neurooncol., 2019 May shRNA TG312894
FYCO1 The role of FYCO1-dependent autophagy in lens fiber cell differentiation. Autophagy, 2022 Aug shRNA TL304437
FZD10 FZD10 regulates cell proliferation and mediates Wnt1 induced neurogenesis in the developing spinal cord BioRxiv, 2019 Jul shRNA TF312885
FZD2 Suppression of hepatocellular carcinoma cell proliferation by short hairpin RNA of frizzled 2 with Sonazoid-enhanced irradiation Int. J. Oncol., 2016 Jan shRNA TR312884
FZD2 Gastric cancer cell proliferation is suppressed by frizzled-2 short hairpin RNA Int. J. Oncol., 2015 Mar shRNA TR312884
FZD2 Short hairpin RNA of frizzled-2 suppresses the proliferation of hepatocellular carcinoma cells ONCOLOGY LETTERS, 2014 Aug shRNA TR312884
FZD2 Frizzled-2: A potential novel target for molecular pancreatic cancer therapy Oncology Letters 74, 2013 Nov shRNA TR312884
FZD2 Identification of Predictive Markers of Response to the MEK1/2 Inhibitor Selumetinib (AZD6244) in K-ras–Mutated Colorectal Cancer Mol. Cancer Ther., Dec 2010; 9: 3351 - 3362, 2010 Dec shRNA TR312884
FZD5 Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis Angiogenesis, 2017 Aug shRNA TG312882
FZD7 Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs Cells, 2021 Jan shRNA TG500742
G3bp1 GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy PLoS ONE, 2015 Dec shRNA TL515376
GABPA Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas. Molecular cell, 2022 Oct shRNA TL312871
Galm Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series Genome Med, 2016 Sep shRNA TG700891
GAS2 The Interferon Consensus Sequence Binding Protein (ICSBP) Decreases Bcatenin-Activity in Myeloid Cells By Repressing GAS2 Transcription Mol. Cell. Biol., Oct 2010; 30: 4575 - 4594, 2010 Oct shRNA TR511218
Gata3 Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity Journal for Immunotherapy of Cancer, 2022 Nov shRNA TL513036
GATA4 GATA-4 upregulates glucose-dependent insulinotropic polypeptide expression in cells of pancreatic and intestinal lineage Mol Cell Endocrinol. 2008 June 11; 287(1-2): 20–29, 2008 Jun shRNA TR500773
GB200002 DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1 Oncogene July 2014, 2014 Jul shRNA HC121827
GBP5 GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (New York, N.Y.), 2012 May shRNA TG304384
GCLC EPITHELIAL AND MESENCHYMAL CELL BIOLOGY: Endogenous Hydrogen Peroxide Regulates Glutathione Redox via Nuclear Factor Erythroid 2-Related Factor 2 Downstream of Phosphatidylinositol 3-Kinase during Muscle Differentiation Am. J. Pathol., Jun 2008; 172: 1529 - 1541., 2008 Jun shRNA TR312813
GDF15 Hypoxia Induces Growth Differentiation Factor 15 to Promote the Metastasis of Colorectal Cancer via PERK-eIF2α Signaling BioMed Research International, 2020 Jan shRNA TR312802
GFP PKR Regulates B56{alpha}-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells J. Biol. Chem., Dec 2008; 283: 35474 - 35485., 2008 Dec shRNA
GFP-tagged siRNA Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia J. Neurosci., Apr 2012; 32: 5024 - 5038., 2012 Apr shRNA
GHITM TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria EMBO Reports, 2022 Nov shRNA TR315671
GHR Growth hormone receptor (GHR) promotes breast cancer progression via the BRAF/MEK/ERK signaling pathway FEBS Open Bio, 2020 Feb shRNA TR312779
GHR Silencing growth hormone receptor inhibits estrogen receptor negative breast cancer through ATP-binding cassette sub-family G member 2 Exp. Mol. Med., 2019 Jan shRNA TR312779
Ghrl Voluntary exercise attenuates obesity-associated inflammation through ghrelin expressed in macrophages. Biochemical and biophysical research communications, 2011 Dec shRNA TL503386
GHSR The suppression of ghrelin signaling mitigates age-associated thermogenic impairment Aging (Albany NY), 2014 Dec shRNA TG506242
GINS4 Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia JCI Insight, 2022 Nov shRNA TL304343
GJA1 Specific N-cadherin-dependent pathways drive human breast cancer dormancy in bone marrow Life science alliance, 2021 Jul shRNA TF312771
GJA1 Connexin hemichannel and pannexin channel electrophysiology: How do they differ? FEBS Lett., Jan 2014., 2014 Jan shRNA TR312771
GJA1 Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of Beta-catenin/connexin43 association Exp Cell Res. 2013 Dec 10;319(20):3065-80, 2013 Dec shRNA TR312771
GJA1 Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors J. Neurosci., Mar 2010; 30: 4197 - 4209, 2010 Mar shRNA TR500808
GJB2 Gap junction β‑2 expression is negatively associated with the estrogen receptor status in breast cancer tissues and is a regulator of breast tumorigenesis Oncol Rep, 2018 Oct shRNA TR312766
GLI1 Modulation of the IL-6 Receptor a Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells J. Immunol., 2015 Aug shRNA TG312756
GLI1 Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells Cancer Res., Feb 2011; 71: 1092 - 1102, 2011 Feb shRNA TR312756
GLI2 Novel Molecular Mechanism of Regulation of CD40 Ligand by the Transcription Factor GLI2 J. Immunol., 2017 Jun shRNA TR312755
GLI2 Hedgehog and TGFß signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma Oncotarget, 2016 Nov shRNA TR312755
GLI2 Modulation of the IL-6 Receptor a Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells J. Immunol., 2015 Aug shRNA TG312755
GLI2 Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells Cancer Res., Feb 2011; 71: 1092 - 1102, 2011 Feb shRNA TR312755
GOLGA2 GOLGA2/GM130, cis-Golgi Matrix Protein, is a Novel Target of Anticancer Gene Therapy Molecular Therapy doi:10.1038/mt.2012.125, 2012 Jun shRNA TR312706
GOT1 Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-ß/Smad pathway in vascular smooth muscle cells Sci Rep, 2016 Jan shRNA TF709215
Got1 Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling Cell Death Dis, 2014 May shRNA TF709215
GOT2 Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-ß/Smad pathway in vascular smooth muscle cells Sci Rep, 2016 Jan shRNA TF709767
Got2 Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk/MAP kinase pathway mediated by cAMP/PKA signaling Cell Death Dis, 2014 May shRNA TF709767
GPAT3 GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis J. Lipid Res., Jul 2010; 51: 1971 - 1981, 2010 Jul shRNA TR307398