siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Hck Abl-mediated PI3K activation regulates macrophage podosome formation. Journal of cell science, 2021 Jun siRNA SR416688
HCLS1 SDF1a-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells Eur. J. Immunol., 2014 Oct siRNA SR302078
HDAC1 CaMKII exacerbates heart failure progression by activating class I HDACs J. Mol. Cell. Cardiol., 2020 Sep siRNA SR505395
HDAC1 Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells Biochim Biophys Acta Gene Regul Mech, 2020 Jan siRNA SR505395
HDAC1 Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia The Journal of Biological Chemistry, 2016 Feb siRNA SR320458
HDAC3 CaMKII exacerbates heart failure progression by activating class I HDACs J. Mol. Cell. Cardiol., 2020 Sep siRNA SR505399
HDAC3 Acetylation of CCAR2 establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition Cancer Res., 2019 Jan siRNA SR505399
HDAC3 Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon Clin Epigenetics, 2015 Sep siRNA SR305837
HDAC6 Histone deacetylase 6 promotes insulin resistance via deacetylating phosphatase and tensin homolog (PTEN) in ovarian OVCAR-3 cells International Journal of Clinical and Experimental Pathology, 2016 Jul siRNA HP209063
HDAC7 HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients Oncogene, 2020 Jul siRNA SR309850
HELLS HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots Genes & Development, 2020 Mar siRNA SR302088
HELLS HELLS and PRDM9 form a Pioneer Complex to Open Chromatin at Meiotic Recombination Hotspots bioRxiv, 2019 Sep siRNA SR302088
HES1 Adropin preserves the blood-brain barrier through a Notch1/Hes1 pathway after intracerebral hemorrhage in mice J. Neurochem.2017, 2017 Oct siRNA SR408110
HES3 Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics Scientific Reports, 2013 Feb siRNA SR318208
HIF1A Enhanced BDNF Actions Following Acute Hypoxia Facilitate HIF-1α-Dependent Upregulation of Cav3-T-Type Ca2+ Channels in Rat Cardiomyocytes Membranes, 2021 Jun siRNA SR320469
HIF1A Arylamine N-acetyltransferase 1 regulates expression of matrix metalloproteinase 9 in cancer cells: role of HIF1-α Mol. Pharmacol., 2019 Aug siRNA SR320469
HIF1A LRG1 promotes keratinocyte migration and wound repair through regulation of HIF-1α stability J. Invest. Dermatol., 2019 Jul siRNA SR320469
HIF1A LRG1 promotes keratinocyte migration and wound repair through regulation of HIF-1α stability J. Invest. Dermatol., 2019 Jul siRNA SR420554
HIF1A Energy stress-induced lncRNA HAND2-AS1 represses HIF1α-mediated energy metabolism and inhibits osteosarcoma progression American journal of Cancer Research, 2018 Mar siRNA SR320469
HIF1A Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts Oncotarget, 2018 Jan siRNA SR320469
HIF1A Global metabolic profiling identifies a pivotal role of proline and hydroxyproline metabolism in supporting hypoxic response in hepatocellular carcinoma Clin. Cancer Res.2017, 2017 Oct siRNA SR302102
HIF1A Bone marrow adipocytes promote the warburg phenotype in metastatic prostate tumors via HIF-1a activation Oncotarget, 2016 Aug siRNA SR302102
HIF1A SOX2 Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3/HIF-a Signaling Int J Mol Sci, 2015 Sep siRNA SR302102
HIF1A Hypoxia Inducible Regulation of Placental BOK Expression Biochem. J., 2014 May siRNA SR302102
HIF1A VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy Clin. Cancer Res., 2014 May siRNA SR302102
HIF3A A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin Cell. Mol. Life Sci., 2019 Nov siRNA SR312024
HIGD1B HIGD‑1B inhibits hypoxia‑induced mitochondrial fragmentation by regulating OPA1 cleavage in cardiomyocytes Molecular medicine reports, 2021 Aug siRNA SR324184
HJV The functional role of hemojuvelin in acute ischemic stroke J. Cereb. Blood Flow Metab., 2019 Jul siRNA SR315661
HK2 A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging Cell, 2020 Feb siRNA SR421182
HMCN1 Hemicentin 1 influences podocyte dynamic changes in glomerular diseases Am. J. Physiol. Renal Physiol., 2018 Feb siRNA SR313256
HMGA2 Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer Nat Commun, 2016 Feb siRNA SR305363
HMGB1 High mobility group box-B1 (HMGB1) mediates the hypoxia-induced mesenchymal transition of osteoblast cells via activating ERK/JNK signaling Cell Biol. Int., 2016 Apr siRNA SR302140
HMGB1 Correlation of HMGB1 expression to progression and poor prognosis of adenocarcinoma and squamous cell/adenosquamous carcinoma of gallbladder Am J Transl Res, 2015 Oct siRNA SR302140
HMGB1-PS2 Chronic morphine-mediated upregulation of high mobility group box 1 in the spinal cord contributes to analgesic tolerance and hyperalgesia in rats Neurotherapeutics, 2019 Dec siRNA SR506455
HMGB3 Regulation of HMGB3 by antitumor miR-205-5p inhibits cancer cell aggressiveness and is involved in prostate cancer pathogenesis J. Hum. Genet., 2017 Dec siRNA SR302142
HMGCS1 The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer PLoS ONE, 2020 Jul siRNA SR302147
HMGN2 HMGN2 Inducibly Binds a Novel Transactivation Domain in Nuclear PRLr to Coordinate Stat5a-Mediated Transcription Mol. Endocrinol., Sep 2011; 25: 1550 - 1564., 2011 Oct siRNA SR302144
HNRNPA1 TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs J. Immunol., 2017 Jul siRNA SR410579
HNRNPA1 Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells Oncogene, 2015 Nov siRNA SR302164
HNRNPD AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1 Oncogenesis, 2020 Aug siRNA SR320518
HNRNPD AUF1 positively controls angiogenesis through mRNA stabilization-dependent up-regulation of HIF-1α and VEGF-A in human osteosarcoma Oncotarget, 2019 Aug siRNA SR320518
HNRNPD Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development Nat Commun, 2017 Oct siRNA SR302168
HNRNPK RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia Nat Commun, 2018 Mar siRNA SR302173
HNRNPK Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43 Hum. Mol. Genet., 2014 Nov siRNA SR302173
HNRNPL hnRNP L-mediated RNA switches function as a hypoxia-induced translational regulon Biochem. Biophys. Res. Commun., 2019 Jun siRNA SR302174
HNRNPL TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs J. Immunol., 2017 Jul siRNA SR417288
HNRNPL Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis Nucleic Acids Res., 2017 May siRNA SR302174
HNRNPM Heterogeneous nuclear ribonucleoprotein M promotes the progression of breast cancer by regulating the axin/β-catenin signaling pathway Biomedicine & Pharmacotherapy, 2018 Sep siRNA SR303072
HOPX HOPX is methylated and exerts tumour suppressive function through Ras-induced senescence in human lung cancer J. Pathol., 2014 Oct siRNA SR313554
HOXA1 Overexpressed lncRNA ROR Promotes the Biological Characteristics of ox-LDL-Induced HUVECs via the let-7b-5p/HOXA1 Axis in Atherosclerosis Frontiers in Cardiovascular Medicine, 2021 Sep siRNA SR302178