shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
GPAT4 GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis J. Lipid Res., Jul 2010; 51: 1971 - 1981, 2010 Jul shRNA TR306795
Gpbar1 The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis. Journal of immunology (Baltimore, Md. : 1950), 2017 Sep shRNA TG506766
GPER1 Stabilization of MORC2 by estrogen and antiestrogens through GPER1- PRKACA-CMA pathway contributes to estrogen-induced proliferation and endocrine resistance of breast cancer cells Autophagy, 2019 Sep shRNA TG316565
GPER1 Estrogenic transmembrane receptor of GPR30 mediates invasion and carcinogenesis by endometrial cancer cell line RL95-2. Journal of cancer research and clinical oncology, 2012 Jun shRNA TG316565
GPER1 The G protein-coupled receptor GPR30 mediates the proliferative and invasive effects induced by hydroxytamoxifen in endometrial cancer cells. Biochemical and biophysical research communications, 2012 May shRNA TG316565
GPER1 Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway. Cancer science, 2009 Jul shRNA TG316565
GPNMB The Potential Role of the Glycoprotein Osteoactivin/Glycoprotein Nonmetastatic Melanoma Protein B in Pancreatic Cancer Pancreas, 2014 Nov shRNA TG312675
Gpr119 Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol Nature Communications, 2023 Jan shRNA TL507165
GPR132 Serum-borne lipids amplify TLR-activated inflammatory responses J. Leukoc. Biol., 2020 Jul shRNA TG312669
GPR68 Reciprocal regulation of two G protein-coupled receptors sensing extracellular concentrations of Ca2+ and H Proc. Natl. Acad. Sci. U.S.A., 2015 Aug shRNA TF507234
GPSM1 G Protein-Coupled Receptor Kinase-6 Interacts with Activator of G Protein Signaling-3 To Regulate CXCR2-Mediated Cellular Functions J. Immunol., Feb 2014., 2014 Feb shRNA TG713072
Gpx4 Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy. Cell metabolism, 2023 Jan shRNA TL508967
GPX4 Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy. Cell metabolism, 2023 Jan shRNA TR316568
GPX4 DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer Nature, 2021 May shRNA TR316568
GREM1 The bone morphogenetic protein antagonist Gremlin is overexpressed in human malignant mesothelioma. Oncology reports, 2012 Feb shRNA TR312620
GRHL1 EGFR-ERK induced activation of GRHL1 promotes cell cycle progression by up-regulating cell cycle related genes in lung cancer Cell death & disease, 2021 Apr shRNA TR304207
GRM1 GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models Clin. Cancer Res., 2016 Jul shRNA RG214400
GRN The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin Matrix Biol., 2017 Apr shRNA TR312595
GRN Sortilin regulates progranulin action in castration-resistant prostate cancer cells Endocrinology, 2014 Nov shRNA TR312595
GRN Proepithelin is an autocrine growth factor for bladder cancer Carcinogenesis, May 2009; 30: 861 - 868., 2009 May shRNA TR312595
GSK3A Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease J. Neurosci., May 2012; 32: 7392 - 7402., 2012 May shRNA TR320375
GSTM4 Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages Proc. Natl. Acad. Sci. U.S.A., 2016 Oct shRNA TR304180
GSTP1 Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells J. Cell. Physiol., 2019 Feb shRNA TG709221
GSTT2 GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage Molecular Nutrition & Food Research Volume 53 Issue 10, Pages 1245 - 1253, 2009 Sep shRNA TR312581
GTF2I DNA damage response defect in Williams-Beuren syndrome Int. J. Mol. Med., 2017 Mar shRNA TG304176
GTF2I PLA2G16 represents a switch between entry and clearance of Picornaviridae Nature, 2017 Jan shRNA TG304176
Gucy1b1 The β subunit of soluble guanylyl cyclase GUCY1B3 exerts cardioprotective effects against ischemic injury via the PKCε/Akt pathway. Journal of cellular biochemistry, 2020 Jun shRNA TL503002
Gys1 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival The Journal of Cell Biology, 2020 Feb shRNA TF509807
HABP2 Hyaluronic Acid Binding Protein 2 Is a Novel Regulator of Vascular Integrity Arterioscler Thromb Vasc Biol, Mar 2010; 30: 483 - 490, 2010 Mar shRNA TR312532
HAND1 Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome PLoS ONE July 2014, 2014 Jul shRNA TR316857
HAX1 Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration Genes Cancer March 2014, 2014 Mar shRNA TF312515
HCAR2 Hippuric acid and 3-(3-hydroxyphenyl) propionic acid inhibit murine osteoclastogenesis through RANKL-RANK independent pathway J. Cell. Physiol., 2019 Jul shRNA TR511005
HDAC1 Chronic sun exposure is associated with distinct histone acetylation changes in human skin Br. J. Dermatol.2017, 2017 Nov shRNA TR312496
HDAC1 Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacteylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B Cell Acute Lymphoblastic Leukemia J. Biol. Chem., 2015 Dec shRNA TG312496
HDAC1 Nuclear Localization of the Transcriptional Regulator MIER1a Requires Interaction with HDAC1/2 in Breast Cancer Cells PLoS ONE Dec 2013., 2013 Dec shRNA TG312496
HDAC1 Histone Deacetylase 2 Cell Autonomously Suppresses Excitatory and Enhances Inhibitory Synaptic Function in CA1 Pyramidal Neurons J. Neurosci., Apr 2013; 33: 5924 - 5929., 2013 Apr shRNA TG312496
HDAC1 Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases Mol. Pharmacol., Jan 2011; 79: 197 - 206, 2011 Jan shRNA TR312496
HDAC2 Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas Clin. Cancer Res., 2019 Apr shRNA TG312495
HDAC2 LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1 J. Cell. Sci., 2015 Nov shRNA TG312495
HDAC2 HDAC2-dependent Deacetylation of MORF4L1 Enhances Its Homodimerization J. Biol. Chem., Jan 2014., 2014 Jan shRNA TG312495
HDAC2 Histone Deacetylase 2 (HDAC2) Protein-dependent Deacetylation of Mortality Factor 4-like 1 (MORF4L1) Protein Enhances Its Homodimerization Journal of Biological Chemistry, 2014 Jan shRNA TG312495
HDAC2 Nuclear Localization of the Transcriptional Regulator MIER1a Requires Interaction with HDAC1/2 in Breast Cancer Cells PLoS ONE Dec 2013., 2013 Dec shRNA TG312495
HDAC2 Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases Mol. Pharmacol., Jan 2011; 79: 197 - 206, 2011 Jan shRNA TR312495
HDAC3 Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model Proc. Natl. Acad. Sci. U.S.A., 2018 Nov shRNA TG500941
HDAC3 Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases Mol. Pharmacol., Jan 2011; 79: 197 - 206, 2011 Jan shRNA TR312494
HDAC4 Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation Oncogene (17 January 2011) doi:10.1038/onc.2010.600 Original Article, 2011 Jan shRNA TR312493
HDAC5 HDAC5, a potential therapeutic target and prognostic biomarker, promotes proliferation, invasion and migration in human breast cancer Oncotarget, 2016 Jun shRNA TG312492
HDAC6 HDAC6 Deacetylates and Ubiquitinates MSH2 to Maintain Proper Levels of MutSa Mol. Cell, 2014 May shRNA TR312491
HDAC6 Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases Mol. Pharmacol., Jan 2011; 79: 197 - 206, 2011 Jan shRNA TR312491
HDAC6 Histone deacetylase 6 interacts with the microtubule-associated protein tau Journal of Neurochemistry. 106(5):2119-2130, September 2008, 2008 Sep shRNA TR312491