siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
IL17RA Interleukin-17 Stimulates STAT3-Mediated Endothelial Cell Activation for Neutrophil Recruitment Cell. Physiol. Biochem., 2015 Aug siRNA SR308461
IL17RC Interleukin-17 Stimulates STAT3-Mediated Endothelial Cell Activation for Neutrophil Recruitment Cell. Physiol. Biochem., 2015 Aug siRNA SR313678
IL17RE IL-17C has a pathogenic role in kidney ischemia/reperfusion Injury Kidney International, 2020 Feb siRNA SR315146
IL1A Comparative Proteomic Analysis of Nuclear and Cytoplasmic Compartments in Human Cardiac Progenitor Cells. Functional Evaluation of IL1A and IMP3 Research Square, 2021 Jan siRNA SR320632
IL1A Cancer cell-derived IL-1a induces CCL22 and the recruitment of regulatory T cells OncoImmunology, 2016 Apr siRNA SR302364
IL1A Cancer cell-derived IL-1a induces CCL22 and the recruitment of regulatory T cells OncoImmunology, 2016 Apr siRNA SR407748
IL1B Prostate tumor cell-derived IL-1β induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms Mol. Cancer Res., 2019 Sep siRNA SR302365
Il1b Cancer cell-derived IL-1a induces CCL22 and the recruitment of regulatory T cells OncoImmunology, 2016 Apr siRNA SR407717
Il1f6 Novel amphiphilic lipid augments the co-delivery of erlotinib and IL36 siRNA into the skin for psoriasis treatment J Control Release, 2016 May siRNA SR403515
IL33 Interleukin-33 predicts poor prognosis and promotes ovarian cancer cell growth and metastasis through regulating ERK and JNK signaling pathways Mol Oncol, 2016 Jan siRNA SR314047
IL37 IL-37 Attenuates Lung Fibrosis by Inducing Autophagy and Regulating TGF-β1 Production in Mice. Journal of immunology (Baltimore, Md. : 1950), 2020 May siRNA SR309020
IL6 Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance PLoS ONE, 2020 Jan siRNA SR302379
IL6R Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance PLoS ONE, 2020 Jan siRNA SR302380
IL6ST Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance PLoS ONE, 2020 Jan siRNA SR320647
IL6ST Discovery of a Novel Orally Active Small-Molecule gp130 Inhibitor for the Treatment of Ovarian Cancer Mol. Cancer Ther., Jun 2013; 12: 937 - 949., 2013 Jun siRNA SR302381
IMP3 Comparative Proteomic Analysis of Nuclear and Cytoplasmic Compartments in Human Cardiac Progenitor Cells. Functional Evaluation of IL1A and IMP3 Research Square, 2021 Jan siRNA SR310633
ING4 MicroRNA‑214 upregulates HIF‑1α and VEGF by targeting ING4 in lung cancer cells Mol Med Report, 2019 Apr siRNA SR309575
INHBA Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity J. Cell. Mol. Med., 2017 Aug siRNA SR302421
INHBB Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia Stem Cells, 2018 Mar siRNA SR302422
INPP4B INPP4B inhibits cell proliferation, invasion and chemoresistance in human hepatocellular carcinoma Onco Targets Ther, 2019 May siRNA SR305819
Inpp5f Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis Molecular Biology of the Cell, 2016 Nov siRNA SR422169
INSR Insulin promotes cell migration by regulating PSA-NCAM Exp. Cell Res, 2017 Mar siRNA SR302436
IPCEF1 HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon PLoS Pathog., 2014 May siRNA SR308675
IRAK3 Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors J. Immunol., 2016 Sep siRNA SR307690
IRAK3 Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M Nat Commun, 2015 Jan siRNA SR307690
IRF3 Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway Biomedicines, 2020 Oct siRNA SR320690
IRF3 MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress Cells, 2020 Jul siRNA SR320690
IRF3 The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways Int J Mol Sci, 2019 Sep siRNA SR320690
IRF3 TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation Int J Mol Sci, 2019 Aug siRNA SR320690
IRF3 The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation J. Immunol., 2018 Apr siRNA SR320690
IRF5 Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway Cells, 2020 Aug siRNA SR320692
IRF7 Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance Carcinogenesis, 2014 Nov siRNA SR302451
IRF9 c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR307030
IRF9 PDGFR-β modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-κB pathway in subarachnoid hemorrhage rats J. Cereb. Blood Flow Metab., 2018 Jan siRNA SR509139
IRF9 FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR307030
IRS2 Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma PLoS ONE, 2015 Dec siRNA SR305694
IRX3 The homeobox factor Irx3 maintains adipogenic identity Metab. Clin. Exp., 2019 Nov siRNA SR312392
ITGA3 Higher Integrin Alpha 3 Beta1 Expression in Papillary Thyroid Cancer Is Associated with Worst Outcome Cancers, 2021 Jun siRNA SR320700
ITGA5 Inhibition of adhesion, migration and of a5ß1 integrin in the HCT-116 colorectal cancer cells treated with the ruthenium drug NAMI-A J. Inorg. Biochem., 2016 Feb siRNA SR302461
ITGAV Self-Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase-Cleavable Linker Adv. Sci., 2018 Jun siRNA SR302468
ITGAV Insulin promotes cell migration by regulating PSA-NCAM Exp. Cell Res, 2017 Mar siRNA SR302468
ITGB1 Hematopoietic-to-mesenchymal transition of adipose tissue macrophages is regulated by integrin β1 and fabricated fibrin matrices Adipocyte, 2017 Apr siRNA SR420242
ITGB1 MMP-2 and MMP-9 expression induced by porphyromonas gingivalis in gingival epithelial cell was influenced by integrinß1 expression Chin J Clinicians, 2015 Jun siRNA SR302470
ITGB3 FSTL1 enhances chemoresistance and maintains stemness in breast cancer cells via integrin β3/Wnt signaling under miR-137 regulation Cancer Biol. Ther., 2018 Oct siRNA SR302472
ITGB3 Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells Nat Commun, 2018 May siRNA SR427515
ITGB3 HOXD3 Plays a Critical Role in Breast Cancer Stemness and Drug Resistance Cell. Physiol. Biochem., 2018 Apr siRNA SR302472
ITGB4 Erratum: A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer iScience, 2020 Nov siRNA SR302473
ITGB4 A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer iScience, 2020 Aug siRNA SR302473
ITGB4 A Non-genetic Mechanism for Chemoresistance in Lung Cancer: The Role of Integrin β4/Paxillin Axis bioRxiv, 2019 Sep siRNA SR302473
ITPKB miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain EMBO Mol Med, 2016 Aug siRNA SR302488