siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
JAG1 Osteosarcoma cell-intrinsic colony stimulating factor-1 receptor functions to promote tumor cell metastasis through JAG1 signaling Am J Cancer Res, 2017 May siRNA SR300128
JMJD6 Demethylase JMJD6 as a new regulator of interferon signaling: effects of HCV and ethanol metabolism Cellular and Molecular Gastroenterology and Hepatology, 2017 Oct siRNA SR308094
JUN c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR320728
JUN FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR320728
JUN A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells Stem Cells, 2014 Aug siRNA SR302499
Kalrn Kalirin, a GEF for Rac1, plays an important role in FSTL-1-mediated glucose uptake in skeletal muscle cells Cellular Signalling, 2016 Oct siRNA SR505738
KAT2A Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay Mol. Carcinog., 2014 Jan siRNA SR301765
KAT5 KAT5 promotes invasion and metastasis through C-MYC stabilization in ATC Endocr. Relat. Cancer, 2019 Jan siRNA SR415850
KCNAB2 Physiological role of Kvβ2 (AKR6) in murine skeletal muscle growth and regulation Acta Physiol (Oxf) 2018, 2018 Apr siRNA SR412390
KCNH2 HERG ???? NF-?B ?????????????? ??????? 2016, 2016 Jul siRNA SR302526
KCNJ2 Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease J. Immunol., 2015 Oct siRNA SR302528
KCNN4 SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer Cell Calcium, 2021 Feb siRNA SR320777
KCNN4 KCa3.1 channel inhibition leads to an ICAM-1 dependent increase of cell-cell adhesion between A549 lung cancer and HMEC-1 endothelial cells Oncotarget, 2017 Dec siRNA SR302550
KCNN4 KCa3.1 as an Effective Target for Inhibition of Growth and Progression of Intrahepatic Cholangiocarcinoma J Cancer, 2017 Aug siRNA SR302550
Kcnn4 Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34 Pharmacol. Res., 2014 May siRNA SR414096
KCNT2 Oxytocin can regulate myometrial smooth muscle excitability by inhibiting the Na± activated K± channel, Slo2.1 J. Physiol. (Lond.) 2018, 2018 Oct siRNA SR317593
KCTD11 KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling Oncotarget, 2017 Jun siRNA SR315580
KDM5A Comparison of Histone H3K4me3 between IVF and ICSI Technologies and between Boy and Girl Offspring International Journal of Molecular Sciences, 2021 Aug siRNA SR304002
KDM5B Geometric regulation of histone state directs melanoma reprogramming Commun Biol, 2020 Jul siRNA SR427794
KDM5B Geometric regulation of histone state directs melanoma reprogramming bioRxiv, 2019 Dec siRNA SR422988
KDM5B Melanoma topology reveals a stem-like phenotype that promotes angiogenesis Sci Adv, 2017 Oct siRNA SR427794
KDR VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy Clin. Cancer Res., 2014 May siRNA SR302557
KDR Increased VEGFR-2 Gene Copy Is Associated with Chemoresistance and Shorter Survival in Patients with Non–Small-Cell Lung Carcinoma Who Receive Adjuvant Chemotherapy Cancer Res., Aug 2011; 71: 5512 - 5521., 2011 Aug siRNA SR302557
KEAP1 Blockage of Nrf2 and autophagy by L-selenocystine induces selective death in Nrf2-addicted colorectal cancer cells through p62-Keap-1-Nrf2 axis Cell Death & Disease, 2022 Dec siRNA SR322898
KHDRBS1 Differential regulation of a placental Sam68 and sFlt-1 gene pathway and the relevance to maternal vitamin D sufficiency Pregnancy Hypertension, 2020 Sep siRNA SR307267
KIF22 KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation Sci Signal, 2018 Jan siRNA SR302592
KIF26B Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity signaling pathway Mol. Biol. Cell, 2016 Jan siRNA SR310475
KIT Cycloartenyl Ferulate Inhibits Paraquat-Induced Apoptosis in HK-2 Cells With the Involvement of ABCC1. Journal of cellular biochemistry, 2016 Oct siRNA SR302578
KIZ PLK1 promotes epithelial-mesenchymal transition and metastasis of gastric carcinoma cells Am J Transl Res, 2016 Nov siRNA SR310998
KL Role of Klotho in migration and proliferation of human dermal microvascular endothelial cells Microvasc. Res., 2016 Sep siRNA SR306202
KLF15 Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection Viruses, 2021 Jun siRNA SR413764
KLF15 Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action Proc. Natl. Acad. Sci. U.S.A., 2020 Aug siRNA SR413764
Klf2 Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022 Jul siRNA SR411977
KLF4 Macrophage MiR-34a Is A Key Regulator of Cholesterol Efflux and Atherosclerosis Molecular Therapy, 2019 Sep siRNA SR426926
KLF4 Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay Mol. Carcinog., 2014 May siRNA SR306162
KLF5 Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer Cancers, 2021 Jan siRNA SR300482
KLHL15 Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection Nat Commun, 2016 Aug siRNA SR312886
KLHL2 High potassium concentration regulates the WNK3‒SPAK‒NKCC1 phosphorylation cascade via kelch-like protein 2 in mouse vascular smooth muscle cells Journal of Medical and Dental Sciences, 2018 Mar siRNA SR417910
KLRD1 Regulation and Gene Expression Profiling of NKG2D Positive Human Cytomegalovirus-Primed CD4 + T-Cells PLoS ONE, 2012 Aug siRNA SR302586
KPNB1 PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1 J. Cell Biol., 2018 Mar siRNA SR302594
KRAS EIF1AX and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC Cancer Discov, 2018 Oct siRNA SR320806
KRAS Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C Oncotarget, 2016 Dec siRNA SR320806
KRAS Modulation of EZH2 expression by MEK-ERK or PI3K-AKT signaling in lung cancer is dictated by different KRAS oncogene mutations Cancer Res., 2015 Dec siRNA SR302601
KREMEN1 DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage J Neuroinflammation, 2020 Apr siRNA SR415307
L1TD1 Embryonic stem cell-related protein L1TD1 is required for cell viability, neurosphere formation and chemoresistance in medulloblastoma Stem Cells Dev., 2015 Jul siRNA SR310168
LAMC1 Systems analysis identifies miR-29b regulation of invasiveness in melanoma Mol. Cancer, 2016 Nov siRNA SR302649
LAMC2 Aberrant expression of laminin ?2 correlates with poor prognosis and promotes invasion in extrahepatic cholangiocarcinoma J Surg Res. 2013 Oct 2. pii: S0022-4804(13)00850-0, 2013 Oct siRNA SR302651
LAMP1 Dihydrolipoic acid enhances autophagy and alleviates neurological deficits after subarachnoid hemorrhage in rats Experimental neurology, 2021 May siRNA SR508640
Lamp1 Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat Stroke, 2018 Jan siRNA SR508640
Lamp2 Upregulated monocyte expression of PLIN2 is associated with early arterial injury in children with overweight/obesity Atherosclerosis, 2021 May siRNA SR426747