siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
LAMP2 Upregulated Monocyte Expression of Plin2 Depends Upon Proteasome Impairment and is Associated with Early Atherosclerosis in Obese Children Research Square, 2020 Sep siRNA SR413786
LAMP2 Lysosome-associated membrane protein-2 deficiency increases the risk of reactive oxygen species-induced ferroptosis in retinal pigment epithelial cells Biochem. Biophys. Res. Commun., 2019 Oct siRNA SR320822
Lamtor1 p18, a novel adaptor protein, regulates pulmonary endothelial barrier function via enhanced endocytic recycling of VE-cadherin FASEB J., 2014 Nov siRNA SR513910
LAMTOR2 LAMTOR2-Mediated Modulation of NGF/MAPK Activation Kinetics during Differentiation of PC12 Cells PLoS ONE e95863 9 4. April 2014, 2014 Apr siRNA SR309134
LAMTOR5 Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses Immunity, 2015 Jun siRNA SR307168
LANCL2 Activation of LANCL2 by BT-11 Ameliorates IBD by Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms Inflammatory Bowel Diseases, 2018 Apr siRNA SR324535
LASP1 Systems analysis identifies miR-29b regulation of invasiveness in melanoma Mol. Cancer, 2016 Nov siRNA SR302655
LATS1 Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ Endocr. Relat. Cancer, 2018 Aug siRNA SR503145
LATS2 miR-650 Promotes the Metastasis and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Directly Inhibiting LATS2 Expression Cell. Physiol. Biochem., 2018 Nov siRNA SR308858
LCK A common signaling pathway leading to degranulation in mast cells and its regulation by CCR1-ligand Allergy, 2020 Jan siRNA SR427042
LCN2 Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection Mol. Cell, 2018 Dec siRNA SR405112
LDHA Glioblastoma-secreted soluble CD44 activates tau pathology in the brain Exp. Mol. Med., 2018 Apr siRNA SR411129
LDLR Lipopolysaccharide Is Cleared from the Circulation by Hepatocytes via the Low Density Lipoprotein Receptor PLoS ONE, 2016 May siRNA SR302668
LEF1 n-Butyl Benzyl Phthalate Promotes Breast Cancer Progression by Inducing Expression of Lymphoid Enhancer Factor 1 PLoS ONE, 2012 Aug siRNA SR309597
LEFTY1 Gefitinib and Luteolin Cause Growth Arrest of Human Prostate Cancer PC-3 Cells via Inhibition of Cyclin G-Associated Kinase and Induction of miR-630 PLoS ONE, 2014 Jun siRNA SR307250
LEMD3 Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus Nat Commun, 2020 May siRNA SR323641
LEPR Leptin Enhances Hepatic Fibrosis and Inflammation in a Mouse Model of Cholestasis The FASEB Journal, 2021 Jan siRNA SR420378
LGALS1 Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin ß1 Cancer Sci., 2014 Sep siRNA SR302674
LGALS3 A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice Cell Reports Medicine, 2021 Aug siRNA SR302676
LGALS3BP Acute Hantavirus Infection Induces Galectin-3 Binding Protein J. Gen. Virol. July 2014, 2014 Jul siRNA SR302677
Lgals8 A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice Cell Reports Medicine, 2021 Aug siRNA SR410253
LGMN Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer/'s disease NATURE COMMUNICATIONS, 2015 Nov siRNA SR303790
LGMN Local mitochondrial-endolysosomal microfusion cleaves the voltage-dependent anion channel 1 to promote survival in hypoxia Mol. Cell. Biol., 2015 Feb siRNA SR303790
LGR4 NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor EMBO J., 2020 Feb siRNA SR310714
LGR5 NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor EMBO J., 2020 Feb siRNA SR322442
LMNA Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesis BMC Cell Biol., 2016 Nov siRNA SR302703
LMO2 Soluble Heparin Binding EGF-like Growth Factor (HB-EGF) is a regulator of GALGT2 expression and GALGT2-dependent muscle and neuromuscular phenotypes Mol. Cell. Biol., 2019 Apr siRNA SR403448
LNX1 Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. Journal of proteome research, 2013 Feb siRNA SR313643
LOXL2 Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane Blood, Oct 2011; 118: 3979 - 3989., 2011 Oct siRNA SR302716
LRG1 LRG1 Suppresses Migration and Invasion of Esophageal Squamous Cell Carcinoma by Modulating Epithelial to Mesenchymal Transition J. Cancer, 2020 Jan siRNA SR314597
LRP1 Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue Scientific reports, 2021 Jun siRNA SR423695
LRP1 LRP1 receptor-mediated immunosuppression of α-MMC on monocytes Int. Immunopharmacol., 2019 Feb siRNA SR302723
LRP1 Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans Arterioscler. Thromb. Vasc. Biol., 2018 Jul siRNA SR302723
LRP1 ApoE4 and Aß Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation J. Neurosci., 2015 May siRNA SR302723
Lrp5 Sclerostin inhibition promotes TNF-dependent inflammatory joint destruction cience Translational Medicine, 2016 Mar siRNA SR423069
LRP6 HLY78 protects blood-brain barrier integrity through Wnt/β-catenin signaling pathway following subarachnoid hemorrhage in rats Brain Res. Bull., 2020 Jun siRNA SR502468
LRP6 HLY78 Attenuates Neuronal Apoptosis via the LRP6/GSK3β/β-Catenin Signaling Pathway After Subarachnoid Hemorrhage in Rats Neurosci Bull, 2020 Jun siRNA SR502468
LRRC2 Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function PLoS ONE, 2017 Feb siRNA SR312419
LTBP4 Increased expression of latent TGF-β-binding protein 4 affects the fibrotic process in scleroderma by TGF-β/SMAD signaling Lab. Invest, 2017 Mar siRNA SR305517
LY6E LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis Oncotarget, 2016 Oct siRNA SR302746
LYPLA1 Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling Cell, 2019 Jan siRNA SR307076
LYST Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study Bosn J Basic Med Sci, 2016 Nov siRNA SR300809
MAD2L1 Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation PLoS One. 2013;8(1):e54577, 2013 Jan siRNA SR302764
MAP1LC3A Deoxyelephantopin induces ROS-mediated autophagy and apoptosis in human colorectal cancer in vitro and in vivo Asian Pac J Trop Biomed, 2020 Feb siRNA SR313569
MAP1LC3B The apoptotic effect of 1'S-1'-Acetoxychavicol Acetate (ACA) enhanced by inhibition of non-canonical autophagy in human non-small cell lung cancer cells PLoS ONE, 2017 Feb siRNA SR313079
MAP2K1 MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma. Cell death discovery, 2023 Feb siRNA SR321446
MAP2K1 Modulation of EZH2 expression by MEK-ERK or PI3K-AKT signaling in lung cancer is dictated by different KRAS oncogene mutations Cancer Res., 2015 Dec siRNA SR303761
MAP2K1 The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux Autophagy, 2015 Jun siRNA SR303761
MAP2K4 Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression Theranostics, 2020 Jan siRNA SR304323
MAP2K6 Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism during Hepatocyte Lipotoxicity J. Cell. Biochem, 2017 Mar siRNA SR303765