shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Inpp5d IVIG activates FcγRIIB-SHIP1-PIP3 Pathway to stabilize mast cells and suppress inflammation after ICH in mice Sci Rep, 2017 Nov shRNA TG516227
INPPL1 The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics J. Cell Biol., Aug 2010; 10.1083/jcb.201005018, 2010 Aug shRNA TR312134
INSIG2 Insulin-induced gene 2 expression correlates with colorectal cancer metastasis and disease outcome IUBMB Life, 2015 Dec shRNA TG303915
INSR Regulación de la captación de glucosa en astrocitos por el eje insulina/IGF-I Thesis, 2014 Oct shRNA TG320387
IPMK Inositol Polyphosphate Multikinase Is a Coactivator of p53-Mediated Transcription and Cell Death Sci. Signal., Apr 2013; 6: ra22., 2013 Apr shRNA TG303904
IPO7 Knockdown of Importin 7 Inhibits Lung Tumorigenesis in K-ras(LA1) Lung Cancer Mice Anticancer Res., 2017 May shRNA TF312126
IRF6 TGFß3 Regulates Periderm Removal through ?Np63 in the Developing Palate J. Cell. Physiol., 2014 Oct shRNA TR312109
IRF7 Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro J Neuroinflammation, 2015 Apr shRNA TR315487
IRF7 Translational control of the innate immune response through IRF-7 Nature 452, 323 - 328 (13 Feb 2008), 2008 Feb shRNA TR315487
Irf8 DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes including interferon regulatory factor 8 Kidney international, 2018 Nov shRNA TG701093
IRF8 Interferon Regulatory Factor 8 Protects Against Cerebral Ischaemic-Reperfusion Injury J. Neurochem., Feb 2014., 2014 Feb shRNA TG701093
IRS1 Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells Growth Factors, Jan 2014., 2014 Jan shRNA TF516309
ISLR Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy Nat Commun, 2018 Dec shRNA TG512833
ITGA2 CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression Oncotarget, 2017 Oct shRNA TG312097
ITGB1 Physical and Functional Interactions between a Glioma Cation Channel and Integrin ß1 Require a-Actinin Am. J. Physiol., Cell Physiol., 2015 Jun shRNA TG320392
ITGB1 Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion J Natl Cancer Inst, Aug 2011; 103: 1162 - 1178., 2011 Aug shRNA TR320392
ITGB1 Extracellular matrix-induced transforming growth factor-beta receptor signaling dynamics. Oncogene, 2010 May shRNA TR320392
ITGB1 Extracellular matrix-induced transforming growth factor-ß receptor signaling dynamics Oncogene (25 January 2010) doi:10.1038/onc.2009.514 Original Article, 2010 Jan shRNA TR320392
ITGB3 Estudio de los mecanismos celulares y moleculares implicados en la adhesión y migración de células de carcinoma pulmonar no microcítico inducidas por TGFß Thesis, 2015 May shRNA TR312082
ITGB3 Inhibition of tumor-associated avß3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo Angiogenesis, 2014 Sep shRNA TR312082
ITGB3 Combined targeting of TGF-beta1 and integrin beta3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer Mol. Cancer, 2014 May shRNA TR312082
ITGB6 Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury The Journal of Clinical Investigation, 2019 Jul shRNA TF312078
ITPR1 IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice Biochim Biophys Acta Mol Basis Dis, 2018 Sep shRNA TR517036
ITPR1 Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism Front Physiol, 2018 Jun shRNA TF517036
JAG1 Osteosarcoma cell-intrinsic colony stimulating factor-1 receptor functions to promote tumor cell metastasis through JAG1 signaling American Journal of Cancer Research, 2017 Apr shRNA TG312059
JAG2 Distinct Biological Roles for the Notch Ligands Jagged-1 and Jagged-2 J. Biol. Chem., Jun 2009; 284: 17766 - 17774, 2009 Jun shRNA TR303860
Jak1 Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia Nature genetics, 2020 Aug shRNA TG511227
JAK2 An activity-dependent determinant of synapse elimination in the mammalian brain Neuron, 2021 Mar shRNA TF320395
JUN ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the , MIF Immune Susceptibility Locus Arthritis & rheumatology (Hoboken, N.J.) 2021, 2021 Apr shRNA TG320397
JUN Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling Oncotarget, 2017 Jan shRNA TG501139
JUN MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells Oncotarget, 2016 Sep shRNA TR320397
Jun Co-inhibition of NF-?B and JNK is synergistic in TNF-expressing human AML J. Exp. Med., 2014 May shRNA TG501139
JUN PNAS Plus: Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation PNAS, Oct 2012; 109: E2875 - E2884., 2012 Oct shRNA TG320397
JUNB Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils Nat. Immunol., 2019 Mar shRNA TF516091
JUNB Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling Oncotarget, 2017 Jan shRNA TG516091
Jund Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling Oncotarget, 2017 Jan shRNA TG501140
JUND Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Requires Cellular Transcription Factor JunD To Upregulate HTLV-1 Antisense Transcription from the 3' Long Terminal Repeat J. Virol., Sep 2012; 86: 9070 - 9078., 2012 Sep shRNA TG312046
JUP Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3{sigma} J. Cell Sci., Jul 2013; 126: 3031 - 3042., 2013 Jul shRNA TG312045
JUP Molecular characterization of the tumor/metastasis suppressor activity of plakoglobin Thesis, 2013 Jan shRNA TG312045
KAT2B PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription Nucleic Acids Res., Jan 2011; 39: 429 - 439, 2011 Jan shRNA TR310589
KAT2B Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation J. Cell Sci., Nov 2010; 123: 3718 - 3726, 2010 Nov shRNA TR310589
Kcna1 Control and Plasticity of the Presynaptic Action Potential Waveform at Small CNS Nerve Terminals Neuron, 2014 Nov shRNA TR713329
Kcnc1 Control and Plasticity of the Presynaptic Action Potential Waveform at Small CNS Nerve Terminals Neuron, 2014 Nov shRNA TR709473
KCNH2 A microtranslatome coordinately regulates sodium and potassium currents in the human heart Elife, 2019 Oct shRNA TG320399
KCNH2 A microtranslatome coordinately regulates sodium and potassium currents in the heart bioRxiv, 2019 Oct shRNA TG320399
Kcnh6 From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion. Cell reports, 2019 Dec shRNA TL512772
KCNK1 Kir2.1 and K2P1 channels reconstitute two levels of resting membrane potential in cardiomyocytes J. Physiol. (Lond.) 2017, 2017 Aug shRNA TF315498
KCNK1 TWIK-1 Two-Pore Domain Potassium Channels Change Ion Selectivity and Conduct Inward Leak Sodium Currents in Hypokalemia Sci. Signal., Jun 2011; 4: ra37., 2011 Jun shRNA TR315498
KCNQ1 Synergistic Restoring Effects of Isoproterenol and Magnesium on KCNQ1-Inhibited Bradycardia Cell Models Cultured in Microelectrode Array Cardiology, Feb 2014., 2014 Feb shRNA TR711664
KCTD5 KCTD5, a novel TRPM4‐regulatory protein required for cell migration as a new predictor for breast cancer prognosis FASEB j., 2020 Apr shRNA TG303786