siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
MAP2K7 Calcium-Ask1-MKK7-JNK2-c-Src Signaling Cascade Mediates Disruption of Intestinal Epithelial Tight Junctions by Dextran Sulfate Sodium Biochem. J., 2014 Nov siRNA SR303766
MAP3K11 MLK3 is a newly identified microRNA-520b target that regulates liver cancer cell migration PLoS ONE, 2020 Mar siRNA SR320985
MAP3K11 Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism during Hepatocyte Lipotoxicity J. Cell. Biochem, 2017 Mar siRNA SR302913
MAP3K13 Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53 Cancer Res., 2017 Jul siRNA SR306071
MAP3K19 The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells J. Biol. Chem., 2020 Apr siRNA SR325092
MAP3K3 HIV-1 and HIV-2 differentially regulate NF-κB activity during the late stages of the replication cycle through BST-2/tetherin antagonism bioRxiv, 2020 May siRNA SR320953
MAP3K5 Calcium-Ask1-MKK7-JNK2-c-Src Signaling Cascade Mediates Disruption of Intestinal Epithelial Tight Junctions by Dextran Sulfate Sodium Biochem. J., 2014 Nov siRNA SR302865
MAP3K7 HIV-1 and HIV-2 differentially regulate NF-κB activity during the late stages of the replication cycle through BST-2/tetherin antagonism bioRxiv, 2020 May siRNA SR321958
MAPK1 Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer Cancer Cell, 2020 Jan siRNA SR412074
MAPK1 Mixed Lineage Kinase 3 Mediates the Induction of CXCL10 by a STAT1-Dependent Mechanism during Hepatocyte Lipotoxicity J. Cell. Biochem, 2017 Mar siRNA SR303751
MAPK1 MAPK1E322K mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin Oncotarget, 2016 Mar siRNA SR303751
MAPK10 19q13 KRAB zinc-finger protein ZNF471 activates MAPK10/JNK3 signaling but is frequently silenced by promoter CpG methylation in esophageal cancer Theranostics, 2020 Jan siRNA SR303759
MAS1 20-Hydroxyecdysone activates the protective arm of the renin angiotensin system via Mas receptor bioRxiv, 2020 Apr siRNA SR410777
MAX The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension Communications Biology, 2023 Aug siRNA SR302818
MAZ The MAZ transcription factor is a downstream target of the oncoprotein Cyr61/CCN1 and promotes pancreatic cancer cell invasion via CRAF-ERK signaling J. Biol. Chem., 2018 Feb siRNA SR302819
MCL1 Autophagy inhibition by sustained over-production of IL-6 contributes to arsenic-induced carcinogenesis Cancer Res., 2014 May siRNA SR302834
MCM2 MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach Sci Rep, 2017 Oct siRNA SR302835
MCU The whole cell Ca2+ release-activated Ca2+ current ICRAC is regulated by the mitochondrial Ca2+ uniporter channel and is independent of extracellular and cytosolic Na J. Physiol. (Lond.) 2018, 2018 Dec siRNA SR508660
Mcu Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria Nat Commun, 2018 Jan siRNA SR508660
Mcu Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca2+ Oscillations, Store-Operated Ca2+ Entry and Ca2+-Dependent Gene Expression in Response to Receptor Stimulation PLoS ONE July 2014, 2014 Jul siRNA SR508660
MDM2 Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants Communications Biology, 2021 Dec siRNA SR302849
MDM2 PEPD is a pivotal regulator of p53 tumor suppressor Nature Communications, 2017 Dec siRNA SR302849
MDM2 Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner Oncogenesis, 2017 Apr siRNA SR302849
MECOM The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia PLoS Genet., 2016 Sep siRNA SR301479
Mef2a Chronic oxytocin-driven alternative splicing of Crfr2α induces anxiety. Molecular psychiatry, 2021 May siRNA SR504191
Mef2a Oxytocin alters the morphology of hypothalamic neurons via the transcription factor myocyte enhancer factor 2A (MEF-2A). Molecular and cellular endocrinology, 2019 May siRNA SR504191
MEF2A p38MAPK Signaling Enhances Glycolysis Through the Up-Regulation of the Glucose Transporter GLUT-4 in Gastric Cancer Cells Cell. Physiol. Biochem., 2015 Apr siRNA SR302855
MEMO1 HRG/HER2/HER3 signaling promotes AhR-mediated Memo-1 expression and migration in colorectal cancer Oncogene, 2016 Dec siRNA SR309508
MEN1 Menin Associates with the Mitotic Spindle and is Important for Cell Division Endocrinology, 2019 Jun siRNA SR302867
Meox2 Regulation of mesenchymal signaling in palatal mucosa differentiation Histochem. Cell Biol., 2017 Dec siRNA SR408862
MET Oncogenic properties of the antisense lncRNA COMET in BRAF- and RET-driven papillary thyroid carcinomas Cancer Res., 2019 Mar siRNA SR302873
MET Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma Cancer Biol. Ther., 2018 Oct siRNA SR302873
Met p66ShcA Promotes Breast Cancer Plasticity by Inducing an Epithelial to Mesenchymal Transition Mol. Cell. Biol. July 2014, 2014 Jul siRNA SR422761
MET 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met. Biochemical and biophysical research communications, 2013 Nov siRNA SR302873
METTL3 N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis Nat. Struct. Mol. Biol., 2017 Oct siRNA SR311159
METTL7B Human METTL7B is an alkyl thiol methyltransferase that metabolizes hydrogen sulfide and captopril Scientific reports, 2021 Mar siRNA SR316261
MFAP5 Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling Clin Transl Oncol, 2019 Jun siRNA SR305355
MFN1 Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging Aging Cell, 2017 Jul siRNA SR310844
MFN2 MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α Biochim. Biophys. Acta, 2018 May siRNA SR419873
MGAT5 Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Oncotarget, 2020 Dec siRNA SR320966
MGAT5 Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased ß1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding PLoS ONE, 2016 Jan siRNA SR302886
MICAL1 Sema6A and Mical1 control cell growth and survival of BRAF V600E human melanoma cells Oncotarget, 2015 Feb siRNA SR312119
MIF Macrophage migration inhibitory factor-CD74 interaction regulates the expression of programmed cell death ligand 1 in melanoma cells Cancer Sci., 2019 Jul siRNA SR302900
MIOX Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors Biomedicines, 2020 Jul siRNA SR310776
MIOX Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule J. Clin. Invest., 2019 Aug siRNA SR310776
MIOX Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI J. Am. Soc. Nephrol., 2016 Nov siRNA SR310776
Mkx Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development The Journal of Biological Chemistry, 2023 Feb siRNA SR411975
MLXIP TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion J. Biochem., 2019 Nov siRNA SR307841
MLXIPL TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion J. Biochem., 2019 Nov siRNA SR309520
MLXIPL Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma Cell Cycle, 2018 Jul siRNA SR309520