shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
KCTD5 KCTD5 and Ubiquitin Proteasome Signaling Are Required for Helicobacter pylori Adherence Front Cell Infect Microbiol, 2017 Oct shRNA TG303786
KDM1A Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan Nature Communications, 2022 Jan shRNA TL316984
KDM1A Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription PLoS Biol., 2015 Apr shRNA TF316984
KDM3A The Hypoxia-Inducible Epigenetic Regulators Jmjd1a and G9a Provide a Mechanistic Link between Angiogenesis and Tumor Growth Mol. Cell. Biol. July 2014, 2014 Jul shRNA TG303857
KDM4B MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis Frontiers in Cell and Developmental Biology, 2021 Mar shRNA TR312052
KDM6B Folic Acid Remodels Chromatin on Hes1 and Neurog2 Promoters during Caudal Neural Tube Development J. Biol. Chem., Nov 2010; 285: 36922 - 36932, 2010 Nov shRNA TR320873
KDR CD133(+) cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma Sci Rep, 2017 Jan shRNA TR320400
KDR CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development Cell Res., 2015 Feb shRNA TG320400
KDR Autocrine VEGF signaling promotes cell proliferation and modulates the sorafenib treatment efficacy in hepatocellular carcinoma Hepatology, 2014 May shRNA TG320400
KHK Ketohexokinase-Dependent Metabolism of Fructose Induces Proinflammatory Mediators in Proximal Tubular Cells . Am. Soc. Nephrol., Mar 2009; 20: 545 - 553., 2009 Mar shRNA TR311985
KHSRP KHSRP-bound small nucleolar RNAs associate with promotion of cell invasiveness and metastasis of pancreatic cancer Oncotarget, 2020 Jan shRNA TR311984
KHSRP KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons PLoS ONE e79255, 2013 Nov shRNA TG311984
KIF11 Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms Sci Rep, 2018 Nov shRNA TG501174
KIF13B Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms Sci Rep, 2018 Nov shRNA TG517925
Kif19a Production of transgenic mice by random recombination of targeted genes in female germline stem cells J Mol Cell Biol, Dec 2010; 10.1093/jmcb/mjq043, 2010 Dec shRNA TR517467
KIF20A Aberrant KIF20A Expression Is Associated with Adverse Clinical Outcome and Promotes Tumor Progression in Prostate Cancer Dis. Markers, 2019 Sep shRNA TG311916
KIF20A KIF20A Affects the Prognosis of Bladder Cancer by Promoting the Proliferation and Metastasis of Bladder Cancer Cells Disease Markers, 2019 Apr shRNA TG311916
KIF20A KIF20A-Mediated RNA Granule Transport System Promotes the Invasiveness of Pancreatic Cancer Cells Neoplasia, 2014 Dec shRNA TG311916
KIF21A Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms Sci Rep, 2018 Nov shRNA TG501180
KIF21B Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms Sci Rep, 2018 Nov shRNA TG501181
KIF23 Aberrant KIF20A Expression Is Associated with Adverse Clinical Outcome and Promotes Tumor Progression in Prostate Cancer Disease Markers, 2019 Sep shRNA TG311914
KIF23 KIF20A-Mediated RNA Granule Transport System Promotes the Invasiveness of Pancreatic Cancer Cells Neoplasia (New York, N.Y.), 2014 Dec shRNA TG311914
KIF3A Live-Cell Imaging Evidence for the Ciliary Transport of Rod Photoreceptor Opsin by Heterotrimeric Kinesin-2 J. Neurosci., Aug 2012; 32: 10587 - 10593., 2012 Aug shRNA TR311911
Kif3b Molecular Motor KIF3B Acts as a Key Regulator of Dendritic Architecture in Cortical Neurons Frontiers in Cellular Neuroscience, 2020 Oct shRNA TL501182
KISS1R KISS1R signaling promotes invadopodia formation in human breast cancer cell via ß-arrestin2/ERK Cell. Signal., 2015 Dec shRNA TR303680
KISS1R Regulation of GPR54 Signaling by GRK2 and {beta}-Arrestin Mol. Endocrinol., Oct 2009; 10.1210/me.2009-0013, 2009 Oct shRNA TR303680
KL Klotho upregulation contributes to the neuroprotection of ligustilide against cerebral ischemic injury in mice Eur. J. Pharmacol., 2017 Dec shRNA TG303679
KLF4 Imbalance of a KLF4-miR-7 auto-regulatory feedback loop promotes prostate cancer cell growth by impairing microRNA processing Am J Cancer Res, 2018 Feb shRNA TG316853
KLF4 Putative Tumor-Suppressive Function of Krüppel-Like Factor 4 in Primary Lung Carcinoma Clin. Cancer Res., Sep 2009; 15: 5688 - 5695, 2009 Sep shRNA TR316853
KLF5 Prognostic Value and Function of KLF5 in Papillary Thyroid Cancer Cancers, 2021 Jan shRNA TR311886
Klf5 Role of miR-145 in cardiac myofibroblast differentiation. Journal of molecular and cellular cardiology, 2014 Aug shRNA TG509991
KLF6 Energy Restriction-mimetic Agents Induce Apoptosis in Prostate Cancer Cells in Part through Epigenetic Activation of KLF6 Tumor Suppressor Gene Expression J. Biol. Chem., Mar 2011; 286: 9968 - 9976, 2011 Mar shRNA TR311885
KLHDC8B The Kelch Protein KLHDC8B Guards against Mitotic Errors, Centrosomal Amplification, and Chromosomal Instability J. Biol. Chem., Nov 2012; 287: 39083 - 39093., 2012 Nov shRNA TR318087
KLHDC8B Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells PNAS, Sep 2009; 106: 14920 - 14925, 2009 Sep shRNA TR318087
KLHL34 Epigenetic Regulation of KLHL34 Predictive of Pathologic Response to Preoperative Chemoradiation Therapy in Rectal Cancer Patients Int. J. Radiat. Oncol. Biol. Phys., 2015 Mar shRNA TG307679
KLHL40 Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage Differentiation Dec 2013., 2013 Dec shRNA TG303840
KLK5 Kallikrein-5 Promotes Cleavage of Desmoglein-1 and Loss of Cell-Cell Cohesion in Oral Squamous Cell Carcinoma J. Biol. Chem., Mar 2011; 286: 9127 - 9135, 2011 Mar shRNA TR311870
Kmt2a Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes Epigenetics Chromatin, 2016 Nov shRNA TR517798
KMT2D Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan Nature Communications, 2022 Jan shRNA TL311461
KRT14 Platelet-rich plasma activates AKT signaling to promote wound healing in a mouse model of radiation-induced skin injury J Transl Med, 2019 Aug shRNA TR311838
KRT6A K16 is a further new candidate for homotypic intermediate filament protein interactions. Experimental dermatology, 2011 Jan shRNA TG311830
KRT80 SREBP1 drives KRT80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer bioRxiv, 2018 Jul shRNA TF307833
LAMA3 A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration Developmental cell, 2023 Jan shRNA TL311804
LAMP1 Large Putative PEST-like Sequence Motif at the Carboxyl Tail of Human Calcium Receptor Directs Lysosomal Degradation and Regulates Cell Surface Receptor Level J. Biol. Chem., Feb 2012; 287: 4165 - 4176., 2012 Jan shRNA TR311795
LAMP1 Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand Endocrinology, Oct 2011; 152: 3893 - 3904., 2011 Oct shRNA TR311795
LAMP2 Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane Nat Commun, 2015 Dec shRNA TR311794
LARP1 The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer Nucleic Acids Res., 2015 Dec shRNA TF303581
LARS1 PGC-1α Regulates Cell Proliferation, Migration, and Invasion by Modulating Leucyl-tRNA Synthetase 1 Expression in Human Colorectal Cancer Cells. Cancers, 2022 Dec shRNA TG303577
LCE1H Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren\'s syndrome Cell Death Dis, 2020 Mar shRNA TG503987
Lcn2 Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer Clin. Cancer Res., 2016 Sep shRNA TR511895