siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
NAMPT Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells Biochim. Biophys. Acta, 2013 Nov siRNA SR306835
NAPEPLD A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration Sci Rep, 2019 Nov siRNA SR413245
NAT1 Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway Biochem. Pharmacol., 2016 Nov siRNA SR300003
Nat1 Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice Cell Rep, 2016 Oct siRNA SR408355
NAT2 Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction Nature Communications, 2022 Dec siRNA SR300004
NAT2 Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages Biochem. Biophys. Res. Commun., 2017 Jul siRNA SR300004
NAT2 BAG3-mediated Mcl-1 stabilization contributes to drug resistance via interaction with USP9X in ovarian cancer. International journal of oncology, 2017 Mar siRNA SR300004
NAT8L Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker Cancer Prev Res (Phila), 2015 Oct siRNA SR317479
NCAN Antihypoxic effect of miR-24 in SH-SY5Y cells under hypoxia via downregulating expression of neurocan Biochem. Biophys. Res. Commun., 2016 Jun siRNA SR301035
NCK1 SDF1a-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells Eur. J. Immunol., 2014 Oct siRNA SR303089
NCK1 The adapter proteins ADAP and Nck cooperate in T cell adhesion Mol. Immunol. 72-79 60 1. April 2014, 2014 Apr siRNA SR303089
Nck2 Nck2 deficiency in mice results in increased adiposity associated with adipocyte hypertrophy and enhanced adipogenesis Diabetes, 2016 Jun siRNA SR412820
NCL Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity Sci Rep, 2018 Jul siRNA SR321073
NCL Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription Nucleic Acids Res., 2015 Sep siRNA SR303090
NCL Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-a-inducing protein of Helicobacter pylori Int. J. Cancer, 2013 Nov siRNA SR303090
NDRG1 iTRAQ‑based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia Mol Med Rep, 2020 Oct siRNA SR307046
NDRG2 Suppression of NDRG2 alleviates brain injury after intracerebral hemorrhage through mitigating astrocyte-drived glutamate neurotoxicity via NF-κB/GLT1 signaling Brain Res., 2019 Dec siRNA SR412508
Ndufaf1 Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4 + T cells and is regulated by Fas/FasL signaling Cell Death & Disease, 2022 Jun siRNA SR410958
NDUFV1 Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells Elife, 2017 Feb siRNA SR415063
NECTIN2 MPDZ promotes DLL4-induced Notch signaling during angiogenesis Elife, 2018 Apr siRNA SR321541
NEDD4 NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts Bone Res, 2018 Nov siRNA SR420988
NEDD9 Computational Reconstruction of NF?B Pathway Interaction Mechanisms during Prostate Cancer PLoS Comput. Biol., 2016 Apr siRNA SR303132
Negative Control Promoting effects of MiR-135b on human multiple myeloma cells via regulation of the Wnt/β-catenin/Versican signaling pathway Cytokine, 2021 Mar siRNA SR30004
Negative Control Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1 Inflammation, 2020 Oct siRNA SR30004
Negative Control Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway Biomedicines, 2020 Oct siRNA SR30004
Negative Control Geometric regulation of histone state directs melanoma reprogramming Commun Biol, 2020 Jul siRNA SR30004
Negative Control Molecular characterization of the calcium release channel deficiency syndrome JCI Insight, 2020 Jul siRNA SR30004
Negative Control Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury Heliyon, 2020 Jun siRNA SR30004
Negative Control Melatonin improves uterine-conceptus interaction via regulation of SIRT1 during early pregnancy J. Pineal Res., 2020 May siRNA SR30004
Negative Control FAM110B Inhibits Non-Small Cell Lung Cancer Cell Proliferation and Invasion Through Inactivating Wnt/β-Catenin Signaling OncoTargets and Therapy, 2020 May siRNA SR30004
Negative Control TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination Nat Commun, 2020 May siRNA SR30004
Negative Control The Harsh Microenvironment in Early Breast Cancer Selects for a Warburg Phenotype bioRxiv, 2020 Apr siRNA SR30004
Negative Control Prohibitin 1/2 mediates Dengue-3 entry into human neuroblastoma (SH-SY5Y) and microglia (CHME-3) cells J. Biomed. Sci., 2020 Apr siRNA SR30004
Negative Control Arachidonate 12-Lipoxygenase and 12-Hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer J. Biol. Chem., 2020 Apr siRNA SR30004
Negative Control Myo-Inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulo-Interstitial Injury in Diabetes Diabetes, 2020 Mar siRNA SR30004
negative Control (-)-Epigallocatechin gallate inhibits stemness and tumourigenicity stimulated by AXL receptor tyrosine kinase in human lung cancer cells Sci Rep, 2020 Feb siRNA SR30004
Negative Control Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration Med. Sci. Monit., 2020 Jan siRNA SR30004
Negative Control PARP1 enhances influenza A virus propagation by facilitating degradation of host type I interferon receptor J. Virol., 2020 Jan siRNA SR30004
Negative Control Autophagy inhibition blunts PDGFRA adipose progenitors\' cell-autonomous fibrogenic response to high-fat diet Autophagy, 2020 Jan siRNA SR30004
Negative Control YAP-dependent necrosis occurs in early stages of Alzheimer\'s disease and regulates mouse model pathology Nat Commun, 2020 Jan siRNA SR30004
Negative Control Geometric regulation of histone state directs melanoma reprogramming bioRxiv, 2019 Dec siRNA SR30004
Negative Control Myricetin inhibits Endometriosis growth through Cyclin E1 Downregulation In Vitro and In Vivo The Journal of Nutritional Biochemistry, 2019 Dec siRNA SR30004
Negative Control Fam20C‐mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis FASEB j., 2019 Nov siRNA SR30004
Negative Control PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC Oncotarget, 2019 Nov siRNA SR30004
Negative Control IL-27 posttranslationally regulates Y-box binding protein-1 to inhibit HIV-1 replication in human CD4+ T cells AIDS, 2019 Oct siRNA SR30004
Negative Control Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology Nat Commun, 2019 Sep siRNA SR30004
Negative Control Prostate tumor cell-derived IL-1β induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms Mol. Cancer Res., 2019 Sep siRNA SR30004
Negative Control RELA is Sufficient to Mediate Interleukin-1 (IL-1) Repression of Androgen Receptor Expression and Activity in LNCaP Disease Progression Model bioRxiv, 2019 Sep siRNA SR30004
Negative Control PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps bioRxiv, 2019 Sep siRNA SR30004
Negative Control HELLS and PRDM9 form a Pioneer Complex to Open Chromatin at Meiotic Recombination Hotspots bioRxiv, 2019 Sep siRNA SR30004