shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
LRRFIP1 The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a ß-catenin-dependent pathway Nature Immunology 11, 487-494 (9 May 2010) doi:10.1038/ni.1876 Article, 2010 May shRNA TR311663
LRRK1 Immunosuppressive Cyclosporin A Activates AKT in Keratinocytes through PTEN Suppression The Journal of Biological Chemistry, 2010 Apr shRNA TR200242
LSP1 Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation The American Journal of Pathology, 2018 Jul shRNA TG702934
LSP1 Leukocyte specific protein-1: A novel regulator of hepatocellular proliferation and migration deleted in human HCC Hepatology, 2014 Sep shRNA TG702934
LSR LSR promotes epithelial ovarian cancer cell survival under energy stress through the LKB1-AMPK pathway Biochemical and Biophysical Research Communications, 2021 Jan shRNA TG303412
LTA Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation Cytokine, 2019 Jan shRNA TR316607
LTA4H Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A4 Hydrolase Cancer Res., Dec 2010; 70: 9755 - 9764, 2010 Dec shRNA TR311651
LTA4H [6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase Cancer Res., Jul 2009; 69: 5584 - 5591, 2009 Jul shRNA TR311651
LTC4S Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages Proc. Natl. Acad. Sci. U.S.A., 2016 Oct shRNA TR319192
LY6E LY6E Restricts the Entry of Human Coronaviruses, including the currently pandemic SARS-CoV-2 bioRxiv, 2020 Apr shRNA TR311641
Lypla1 Palmitoylation couples insulin hypersecretion with β cell failure in diabetes. Cell metabolism, 2023 Feb shRNA TL709612
MAD2L1 Phosphoinositide 3-kinase ß regulates chromosome segregation in mitosis Mol. Biol. Cell, Dec 2012; 23: 4526 - 4542., 2012 Dec shRNA TG311623
MAFA Calcineurin/Nuclear Factor of Activated T Cells and MAPK Signaling Induce TNF-{alpha} Gene Expression in Pancreatic Islet Endocrine Cells J. Biol. Chem., Jan 2011; 286: 1025 - 1036, 2011 Jan shRNA TR303385
Mafa Calcineurin/Nuclear Factor of Activated T Cells and MAPK Signaling Induce TNF-? Gene Expression in Pancreatic Islet Endocrine Cells The Journal of Biological Chemistry, 2011 Jan shRNA TG508549
MAFF Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell Rep, 2019 Jul shRNA TF501290
Mageb16 Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives Sci Rep, 2017 Oct shRNA TG321071
MAP1LC3B Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways PLoS ONE, 2015 Aug shRNA TG503902
MAP2K1 Cyclin-dependent kinase 5 contributes to endoplasmic reticulum stress induced podocyte apoptosis via promoting MEKK1 phosphorylation at Ser280 in diabetic nephropathy Cell. Signal, 2016 Dec shRNA TR502589
MAP2K3 The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling J Biol Chem. 2005 Dec 23;280(51):42097-105., 2005 Dec shRNA TR320491
MAP3K8 Tpl2 Is a Key Mediator of Arsenite-Induced Signal Transduction Cancer Res., Oct 2009; 69: 8043 - 8049, 2009 Oct shRNA TR512220
MAP4K4 HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells Cell Death Dis, 2018 Sep shRNA TG320615
MAPK1 p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis Aging (Albany NY) 2019, 2019 Feb shRNA TG502598
Mapk10 Sustained Gq-Protein Signaling Disrupts Striatal Circuits via JNK J. Neurosci., 2016 Oct shRNA TR502599
MAPK14 p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma Oral Oncology, 2016 Jul shRNA TG320309
Mapk8 Sustained Gq-Protein Signaling Disrupts Striatal Circuits via JNK J. Neurosci., 2016 Oct shRNA TR511480
Mapk8 Plumbagin induces apoptosis in lymphoma cells via oxidative stress mediated glutathionylation and inhibition of mitogen-activated protein kinase phosphatases (MKP1/2) Cancer Lett., 2014 Nov shRNA TR511480
Mapk9 Sustained Gq-Protein Signaling Disrupts Striatal Circuits via JNK J. Neurosci., 2016 Oct shRNA TR502601
MAPKAPK2 MAPKAP kinase 2-mediated phosphorylation of HspA1L protects male germ cells from heat stress-induced apoptosis Cell Stress Chaperones, 2019 Oct shRNA TF512620
MAPKAPK2 Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis Mol. Biol. Cell, 2016 Aug shRNA TR320609
MAPKAPK5 The TLK1–MK5 Axis Regulates Motility, Invasion, and Metastasis of Prostate Cancer Cells Cancers, 2022 Nov shRNA TL320583
MAPRE2 EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion FASEB J., 2019 May shRNA TF311571
MAPRE3 EB1- and EB2-dependent anterograde trafficking of TRPM4 regulates focal adhesion turnover and cell invasion FASEB J., 2019 May shRNA TF311570
MAPT Glucocorticoids activate a synapse weakening pathway culminating in tau phosphorylation in the hippocampus Pharmacol. Res., 2017 Apr shRNA TG710015
MAPT Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD J. Neurosci., 2015 Mar shRNA TG710015
Marcks Myristoylated Alanine-Rich protein Kinase C Substrate (MARCKS) expression modulates the metastatic phenotype in human and murine colon carcinoma in vitro and in vivo. Cancer letters, 2013 Jun shRNA TR512267
MBD4 Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4 Cancer Med, 2018 Feb shRNA TG311558
MBD4 CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor Oncogene, 2016 Oct shRNA TG311558
MBD4 Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes. International journal of oncology, 2011 Sep shRNA TG311558
Mbtps2 MBTPS2 exacerbates albuminuria in streptozotocin-induced type I diabetic nephropathy by promoting endoplasmic reticulum stress-mediated renal damage. Archives of physiology and biochemistry, 2022 Aug shRNA TL508125
MCAM CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor Oncogene, 2016 Apr shRNA TG311550
MCL1 ER Stress-Mediated Upregulation of miR-29a Enhances Sensitivity to Neuronal Apoptosis Eur. J. Neurosci., 2016 Jan shRNA TG303313
MCL1 Dinaciclib, a CDK inhibitor promotes proteasomal degradation of Mcl-1 and enhances ABT-737 mediated cell death in malignant human glioma cell lines J. Pharmacol. Exp. Ther., 2015 Nov shRNA TR303313
MCL1 Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis Apoptosis, 2013 Nov shRNA TG303313
MCL1 Survivin Inhibitor YM-155 Sensitizes Tumor Necrosis Factor– Related Apoptosis-Inducing Ligand-Resistant Glioma Cells to Apoptosis through Mcl-1 Downregulation and by Engaging the Mitochondrial Death Pathway J. Pharmacol. Exp. Ther., Aug 2013; 346: 201 - 210., 2013 Aug shRNA TG303313
MCL1 YM-155 Potentiates the Effect of ABT-737 in Malignant Human Glioma Cells via Survivin and Mcl-1 Downregulation in an EGFR-Dependent Context Mol. Cancer Ther., Mar 2013; 12: 326 - 338., 2013 Mar shRNA TG303313
MCL1 Inhibition of NF-{kappa}B Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin J. Biol. Chem., Jun 2010; 285: 19162 - 19172, 2010 Jun shRNA TR303313
MCOLN1 Defective Autophagosome Trafficking Contributes to Impaired Autophagic Flux in Coronary Arterial Myocytes Lacking CD38 Gene Cardiovasc. Res., Jan 2014., 2014 Jan shRNA TR303307
MCOLN2 Zinc Dyshomeostasis Is Linked with the Loss of Mucolipidosis IV-associated TRPML1 Ion Channel J. Biol. Chem., Nov 2010; 285: 34304 - 34308, 2010 Oct shRNA TR303306
MCU Molecular tuning of the axonal mitochondrial Ca2+ uniporter ensures metabolic flexibility of neurotransmission bioRxiv, 2019 Jun shRNA TR704979
MDK Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling Stem Cell Reports, 2016 Aug shRNA TG319183