siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
NFKB1 Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus J Huntingtons Dis, 2018 Aug siRNA SR321103
NFKB2 RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model Prostate, 2020 Feb siRNA SR303162
NFKB2 Biliary tract instillation of a SMAC mimetic induces TRAIL-dependent acute sclerosing cholangitis-like injury in mice Cell Death Dis, 2017 Jan siRNA SR303162
NFKBIB Let-7e modulates the inflammatory response in vascular endothelial cells through ceRNA crosstalk Sci Rep, 2017 Feb siRNA SR303164
NGB Amyloid-β25-35 Upregulates Endogenous Neuroprotectant Neuroglobin via NFκB Activation in vitro J. Alzheimers Dis., 2018 Jul siRNA SR403141
NGFR Neurotrophin Receptors TrkA, p75(NTR), and Sortilin are Increased and Targetable in Thyroid Cancer Am. J. Pathol., 2017 Oct siRNA SR303174
NKX2-3 Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers Proc. Natl. Acad. Sci. U.S.A., 2016 Mar siRNA SR315976
NKX2-5 Binge Alcohol Exposure Triggers Atrial Fibrillation Through T-Type Ca2+ Channel Upregulation via Protein Kinase C (PKC) / Glycogen Synthesis Kinase 3β (GSK3β) / Nuclear Factor of Activated T-Cells (NFAT) Signaling　- An Experimental Account of Holiday Heart Syndrome Circ J, 2020 Oct siRNA SR512716
NKX3-1 OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells Oncogene, 2016 Apr siRNA SR303186
NLRP1 Ubiquitination as a key regulatory mechanism for O 3 -induced cutaneous redox inflammasome activation Redox Biology, 2022 Aug siRNA SR307826
NLRP3 HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon PLoS Pathog., 2014 May siRNA SR314415
NLRX1 Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes Aging cell, 2021 Jun siRNA SR312509
NME4 NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy Cell Death Differ., 2016 Jan siRNA SR404588
NONO NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells Front. Immunol., 2020 Jul siRNA SR321120
NOP2 RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia Nat Commun, 2018 Mar siRNA SR303199
Nos2 The level of nitric oxide regulates lipocalin-2 expression under inflammatory condition in RINm5F beta-cells Biochem. Biophys. Res. Commun., 2016 May siRNA SR500964
NOS2 Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition Cell, 2014 Oct siRNA SR303202
NOS3 Role for reactive oxygen species in flow stimulated inner medullary collecting duct endothelin-1 production Am. J. Physiol. Renal Physiol., 2017 May siRNA SR422386
NOS3 Histone deacetylase inhibitors promote eNOS expression in vascular smooth muscle cells and suppress hypoxia-induced cell growth J. Cell. Mol. Med, 2017 Mar siRNA SR515427
NOS3 MALAT1 and HOTAIR Long Non-Coding RNAs Play Opposite Role in Estrogen-Mediated Transcriptional Regulation in Prostate Cancer Cells Sci Rep, 2016 Dec siRNA SR303203
NOTCH1 Adropin preserves the blood-brain barrier through a Notch1/Hes1 pathway after intracerebral hemorrhage in mice J. Neurochem.2017, 2017 Oct siRNA SR303207
NOTCH1 Zinc finger RNA-binding protein promotes non-small-cell carcinoma growth and tumor metastasis by targeting the Notch signaling pathway Am J Cancer Res, 2017 Oct siRNA SR303207
NOTCH1 The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway Sci Transl Med, 2017 Jul siRNA SR303207
NOTCH1 Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents Biochim. Biophys. Acta, 2016 Apr siRNA SR303207
NOTCH1 Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer Nat Commun, 2016 Feb siRNA SR303207
Notch1 Macrophage-Derived Delta-like 1 Enhances Interleukin-6 and Matrix Metalloproteinase-3 Production by Fibroblast-Like Synoviocytes in Arthritic Mice Arthritis & rheumatology, 2014 Jun siRNA SR423522
NOTCH1 cAMP-responsive Element Modulator a (CREMa) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE) J. Biol. Chem., Dec 2012; 287: 42525 - 42532., 2012 Dec siRNA SR303207
NOTCH2 NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells Oncol. Rep., 2015 Oct siRNA SR303209
Notch2 Macrophage-Derived Delta-like 1 Enhances Interleukin-6 and Matrix Metalloproteinase-3 Production by Fibroblast-Like Synoviocytes in Arthritic Mice Arthritis & rheumatology, 2014 Jun siRNA SR423507
NOTCH3 Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis Neurobiol. Dis., 2014 Dec siRNA SR423462
NOX4 G Protein-Coupled Estrogen Receptor Protects From Angiotensin II-Induced Increases in Pulse Pressure and Oxidative Stress Front Endocrinol (Lausanne) 2019, 2019 Aug siRNA SR506919
NOX4 Protein kinase B mediates insulin-like growth factor 1-induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells J. Cell. Physiol., 2019 Feb siRNA SR506919
NOX4 NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells. Free radical biology & medicine, 2017 Dec siRNA SR323985
NOX4 Role for reactive oxygen species in flow stimulated inner medullary collecting duct endothelin-1 production Am. J. Physiol. Renal Physiol., 2017 May siRNA SR417683
NOX4 Nrf2 mediates redox adaptation in NOX4-overexpressed non-small cell lung cancer cells Exp. Cell Res, 2017 Feb siRNA SR309388
NOX4 NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells Free Radical Biology and Medicine, 2016 Oct siRNA SR309388
Nox4 Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle Life Sci., 2016 Aug siRNA SR309388
NPM1 iTRAQ-based Quantitative Proteomic Analysis of Nasopharyngeal Carcinoma J. Cell. Biochem., 2015 Feb siRNA SR303222
NPRL3 A human minisatellite hosts an alternative transcription start site for NPRL3 driving its expression in a repeat number-dependent manner Hum. Mutat., 2020 Jan siRNA SR305374
NR1I2 Antidiuretic Action of Collecting Duct (Pro)Renin Receptor Downstream of Vasopressin and PGE2 Receptor EP4 J. Am. Soc. Nephrol., 2016 Oct siRNA SR513127
NR1I3 Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox Sci Rep, 2017 Sep siRNA SR306706
NR3C1 Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells Sci Rep, 2018 Oct siRNA SR301960
NR4A2 Pharmacological Stimulation of Nurr1 Promotes Cell Cycle Progression in Adult Hippocampal Neural Stem Cells Int J Mol Sci, 2019 Dec siRNA SR513154
NR4A2 The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis Stem Cell Res, 2016 Sep siRNA SR513154
Nrf1 Icariin Induces Synoviolin Expression through NFE2L1 to Protect Neurons from ER Stress-Induced Apoptosis PLoS ONE, 2015 Mar siRNA SR504532
NRP2 MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion Molecular cancer research : MCR, 2022 Aug siRNA SR305825
NSD2 WHSC1/NSD2 regulates immune infiltration in prostate cancer Journal for immunotherapy of cancer, 2021 Feb siRNA SR305101
NSUN2 Epitranscriptomic Addition of m5C to HIV-1 Transcripts Regulates Viral Gene Expression Cell Host Microbe, 2019 Aug siRNA SR310319
NSUN2 Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression MBio, 2019 Jun siRNA SR310319
NSUN2 Epitranscriptomic Addition of m 5C to HIV-1 Transcripts Regulates Viral Gene Expression SSRN Journal, 2019 May siRNA SR310319