siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
NSUN2 RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia Nat Commun, 2018 Mar siRNA SR310319
NSUN7 ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma Oncology, 2017 Dec siRNA SR312557
NTRK1 Neurotrophin Receptors TrkA, p75(NTR), and Sortilin are Increased and Targetable in Thyroid Cancer Am. J. Pathol., 2017 Oct siRNA SR303249
NTRK1 Nerve Growth Factor Receptor TrkA, a New Receptor in Insulin Signaling Pathway in PC12 Cells J. Biol. Chem., Aug 2013; 288: 23807 - 23813., 2013 Aug siRNA SR303249
NTRK2 Myocardial BDNF regulates cardiac bioenergetics through the transcription factor Yin Yang 1 bioRxiv, 2021 Jan siRNA SR506114
NUAK2 The MicroRNA miR-696 is Regulated by SNARK and Reduces Mitochondrial Activity in Mouse Skeletal Muscle Through Pgc1α Inhibition Molecular Metabolism, 2021 Mar siRNA SR418439
NUAK2 E3 ubiquitin ligase RNF126 affects bladder cancer progression through regulation of PTEN stability Cell death & disease, 2021 Mar siRNA SR418439
NUAK2 The AMPK-related kinase SNARK regulates muscle mass and myocyte survival J. Clin. Invest., 2015 Dec siRNA SR418439
NULL A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells Stem Cells, 2014 Aug siRNA SR300974
NULL A novel function of HER2/Neu in the activation of G2/M checkpoint in response to ?-irradiation Oncogene, 2014 Jun siRNA SR301445
NUP62 Macroautophagy Regulates Nuclear NOTCH1 Activity Through Multiple p62 Binding Sites IUBMB Life, 2018 Oct siRNA SR308418
OAS1 Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR303266
OAS2 Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR303267
OAS3 Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR303268
OASL Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR305676
OBSCN Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis Oncogene, 2014 Nov siRNA SR313312
OCLN Occludin, caveolin-1, and Alix form a multi-protein complex and regulate HIV-1 infection of brain pericytes FASEB J, 2020 Oct siRNA SR321170
OCLN HIV alters gap junction-mediated intercellular communication in human brain pericytes Frontiers in Molecular Neuroscience, 2017 Dec siRNA SR303274
OCLN Occludin regulates glucose uptake and ATP production in pericytes by influencing AMP-activated protein kinase activity J. Cereb. Blood Flow Metab., 2017 Jan siRNA SR303274
OGA Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils FEBS J., 2020 May siRNA SR323224
OGA Linking Cancer Metabolism to DNA Repair and Accelerated Senescence Mol. Cancer Res, 2016 Feb siRNA SR307308
OGT Linking Cancer Metabolism to DNA Repair and Accelerated Senescence Mol. Cancer Res, 2016 Feb siRNA SR305553
OMA1 The Role and Regulation of Mitochondrial Dynamics in Cisplatin Resistance in Human Gynecologic Cancer Cells Thesis, 2015 Jun siRNA SR314494
Oma1 p53 Is Required for Cisplatin-induced Processing of the Mitochondrial Fusion Protein L-Opa1 That Is Mediated by the Mitochondrial Metallopeptidase Oma1 in Gynecologic Cancers The Journal of Biological Chemistry, 2014 Sep siRNA SR416607
OMA1 p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in Gynecologic Cancers J. Biol. Chem., 2014 Aug siRNA SR314494
Opa1 Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria Nat Commun, 2018 Jan siRNA SR505373
OPA1 Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging Aging Cell, 2017 Jul siRNA SR303287
Orai1 The Allergen Der p3 from House Dust Mite Stimulates Store-Operated Ca 2+ Channels and Mast Cell Migration through PAR4 Receptors. Molecular cell, 2019 Feb siRNA SR508429
ORAI1 Association of the IP3R to STIM1 provides a reduced intraluminal calcium microenvironment, resulting in enhanced store-operated calcium entry Sci Rep, 2018 Sep siRNA SR313705
ORAI1 Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression Cell Rep, 2015 Jul siRNA SR313705
ORAI1 A relay mechanism between EB1 and APC facilitate STIM1 puncta assembly at endoplasmic reticulum-plasma membrane junctions. Cell calcium, 2014 Mar siRNA SR313705
ORMDL3 The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes Aging (Albany NY) 2019, 2019 May siRNA SR403232
ORMDL3 Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate J. Immunol, 2017 Mar siRNA SR403232
OSR1 WNK4 is an adipogenic factor and its deletion reduces diet-induced obesity in mice EBioMedicine, 2017 Mar siRNA SR407609
OST4 OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation J. Cell Sci., Jun 2013; 126: 2595 - 2606., 2013 Jun siRNA SR319126
OXSR1 WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4 Sci Rep, 2018 Jun siRNA SR416746
P2RX4 Relative Role of Akt, ERK and CREB in Alcohol-Induced Microglia P2X4R Receptor Expression Alcohol Alcohol., 2016 Mar siRNA SR412195
P2RX7 ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival Oncogene, 2018 Aug siRNA SR321204
P2RY6 Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis J. Biol. Chem, 2017 Feb siRNA SR303329
P4HB Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas Cell Death Dis, 2019 Feb siRNA SR321210
p53 SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1–Trx Complex Mol. Cell. Biol., Apr 2013; 33: 1285 - 1302., 2013 Apr siRNA SR304901
Padi2 ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation Cellular and Molecular Life Sciences, 2022 Feb siRNA SR418983
PAF1 Elevated PAF1-RAD52 axis confers chemoresistance to human cancers. Cell reports, 2023 Jan siRNA SR310177
PAF1 PAF1 Regulates Stem Cell Features of Pancreatic Cancer Cells, Independently of the PAF1 Complex, via Interactions with PHF5A and DDX3 Gastroenterology, 2020 Aug siRNA SR310177
PAF1 Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription Radiat Oncol, 2020 May siRNA SR310177
PAF1 Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1 Gastroenterology, 2019 Sep siRNA SR310177
PAF1 Human RNA polymerase II associated factor 1 complex promotes tumorigenesis by activating c-MYC transcription in non-small cell lung cancer Biochem. Biophys. Res. Commun., 2015 Aug siRNA SR310177
PANX1 Interferon-γ and high glucose-induced opening of Cx43 hemichannels causes endothelial cell dysfunction and damage Biochim Biophys Acta Mol Cell Res, 2020 Apr siRNA SR308480
PANX1 Connexin 43 hemichannels and pannexin-1 channels contribute to the α-synuclein-induced dysfunction and death of astrocytes Glia, 2019 Apr siRNA SR414119
PANX1 Connexin 43 Hemichannel Activity Promoted by Pro-Inflammatory Cytokines and High Glucose Alters Endothelial Cell Function Front Immunol, 2018 Aug siRNA SR414119