shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Negative Control Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells Cell Death Dis, 2018 Mar shRNA TR30015
Negative Control Knockdown of ZEB1 suppressed the formation of vasculogenic mimicry and epithelial-mesenchymal transition in the human breast cancer cell line MDA-MB-231 Mol Med Rep, 2018 Mar shRNA TR30021
Negative Control Reduced N-Type Ca2+Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis J Am Heart Assoc, 2018 Jan shRNA TR30021
Negative Control Sphingosine 1-phosphate regulates proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells via syndecan-1 Prog. Biophys. Mol. Biol.2017, 2017 Nov shRNA TR30021
Negative Control Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy Autophagy, 2017 Oct shRNA TR30013
Negative Control Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation J. Virol., 2017 Oct shRNA TR30021
Negative Control Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease Aging Cell, 2017 Jul shRNA TR30013
Negative Control An E2F1/MiR-17-92 Negative Feedback Loop mediates proliferation of Mouse Palatal Mesenchymal Cells Sci Rep, 2017 Jul shRNA TR30013
Negative Control RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5 PLoS ONE, 2017 Jun shRNA TR30003
Negative Control Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas J. Clin. Invest, 2017 Mar shRNA TR30013
Negative Control Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination Nat Commun, 2017 Feb shRNA TR30021
Negative Control Hyperglycemia-induced Changes in ZIP7 and ZnT7 Expression Cause Zn(2+) Release from the Sarco(endo)plasmic Reticulum and Mediate ER-stress in the Heart Diabetes, 2017 Feb shRNA TR30033
Negative Control PLA2G16 represents a switch between entry and clearance of Picornaviridae Nature, 2017 Jan shRNA TR30013
Negative Control Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration Nat Commun, 2017 Jan shRNA TR30021
Negative Control Inhibiting the cytoplasmic location of HMGB1 reverses cisplatin resistance in human cervical cancer cells Mol Med Rep, 2017 Jan shRNA TR30013
Negative Control DNA damage response defect in Williams‑Beuren syndrome INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2017 Jan shRNA TR30013
Negative control Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation EMBO J., 2016 Dec shRNA TR30015
Negative Control Silencing peroxiredoxin-2 sensitizes human colorectal cancer cells to ionizing radiation and oxaliplatin Cancer Lett, 2016 Dec shRNA TR30015
negative control Identification of CTCF as a master regulator of the clustered protocadherin genes Nucleic Acids Res., Dec 2011; 10.1093/nar/gkr1260., 2011 Dec shRNA
NEIL1 Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase J. Biol. Chem., Jan 2009; 10.1074/jbc.M807006200., 2009 Apr shRNA TR307276
NEK3 Identification of NEK3 Threonine 165 as a Novel Regulatory Phosphorylation Site that Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration J. Biol. Chem., 2016 Aug shRNA TF320430
NES Identification and Cytoprotective Function of a Novel Nestin Isoform, Nes-S, in Dorsal Root Ganglia Neurons J. Biol. Chem., Mar 2013; 288: 8391 - 8404., 2013 Mar shRNA TR311207
Neurod1 MiR-30a-5p and miR-153-3p regulate LPS-induced neuroinflammatory response and neuronal apoptosis by targeting NeuroD1 BMB Reports, 2022 Sep shRNA TL710234
NF2 Expression of P2X7 Receptor Increases In Vivo Tumor Growth Cancer Res., Jun 2012; 72: 2957 - 2969., 2012 Jun shRNA TR316639
NFATC1 TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways Sci Rep, 2016 Jul shRNA TG302973
NFATC2 NFATC2 Modulates Radiation Sensitivity in Dermal Fibroblasts From Patients With Severe Side Effects of Radiotherapy Frontiers in Oncology, 2020 Dec shRNA TF311198
NFATC2 An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells Oncogene, 2019 May shRNA TF311198
Nfatc2 Transcriptional regulation of SPROUTY 2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3 Leukemia, 2016 Sep shRNA TG516359
NFATC2 NFATc2 is an intrinsic regulator of melanoma dedifferentiation Oncogene, 2015 Sep shRNA TF311198
NFATC2 NFAT Targets Signaling Molecules to Gene Promoters in Pancreatic ß Cells Mol. Endocrinol., 2014 Dec shRNA TG516359
NFATC2 CD3-T Cell Receptor Co-stimulation through SLAMF3 and SLAMF6 Receptors Enhances RORt Recruitment to the IL17A Promoter in Human T Lymphocytes J. Biol. Chem., Nov 2012; 287: 38168 - 38177., 2012 Nov shRNA TG311198
NFE2L2 Effect of the Nrf2-ARE signaling pathway on biological characteristics and sensitivity to sunitinib in renal cell carcinoma Oncol Lett, 2019 Jun shRNA TG311194
NFE2L2 Oxidative stress-elicited YY1 potentiates antioxidative response via enhancement of NRF2-driven transcriptional activity: A potential neuronal defensive mechanism against ischemia/reperfusion cerebral injury Biomed. Pharmacother., 2018 Sep shRNA TR515053
NFE2L2 Roles of ROS, Nrf2, and autophagy in cadmium-carcinogenesis and its prevention by sulforaphane Toxicol. Appl. Pharmacol., 2018 Jun shRNA TG311194
NFE2L2 Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells J. Biol. Chem, 2017 Mar shRNA TG311194
NFE2L2 Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells Toxicol. Appl. Pharmacol., 2016 Sep shRNA TG311194
Nfe2l2 1,4-Naphthoquinone, a pro-oxidant, ameliorated radiation induced gastro-intestinal injury through perturbation of cellular redox and activation of Nrf2 pathway Drug Discov Ther, 2016 Apr shRNA TF515053
NFE2L2 Anti-oncogenic and oncogenic properties of Nrf2 in arsenic-induced carcinogenesis J. Biol. Chem., 2015 Sep shRNA TG311194
NFE2L2 ROS/Autophagy/Nrf2 Pathway Mediated Low-Dose Radiation Induced Radio-Resistance in Human Lung Adenocarcinoma A549 Cell Int. J. Biol. Sci., 2015 Jun shRNA TG311194
NFKB1 Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis MBio, 2016 Jun shRNA TR318700
NFKB1 Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling British Journal of Cancer 104, 128-137 (7 December 2010) doi:10.1038/sj.bjc.6606013 Full Pape, 2010 Dec shRNA TR516641
NIT1 A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/ß-catenin signalling pathway Cell Discovery, 2016 Jan shRNA TG311168
NKD2 Naked2 Acts as a Cargo Recognition and Targeting Protein to Ensure Proper Delivery and Fusion of TGF-{alpha}-containing Exocytic Vesicles at the Lower Lateral Membrane of Polarized MDCK Cells Mol Biol Cell. 2007 Aug;18(8):3081-93., 2007 Aug shRNA TR302950
NKX2-5 Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome PLoS ONE July 2014, 2014 Jul shRNA TR311165
Nlgn2 Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility Proceedings of the National Academy of Sciences of the United States of America, 2018 Jan shRNA TG516880
NLK Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells Cell Rep, 2019 Mar shRNA TF501483
NLRP1 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma Oncogene, 2017 Mar shRNA TG303052
NLRP3 Contribution of cathepsin B-dependent Nlrp3 inflammasome activation to nicotine-induced endothelial barrier dysfunction Eur. J. Pharmacol., 2019 Nov shRNA TG510752
NLRP3 Procyanidin B2 protects rats from paraquat-induced acute lung injury by inhibiting NLRP3 inflammasome activation Immunobiology, 2018 Oct shRNA TR510752
NLRP3 Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation Oncotarget, 2016 Nov shRNA TG510752