siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Panx1 Cannabinoids prevent the amyloid ß-induced activation of astroglial hemichannels: A neuroprotective mechanism Glia, 2016 Oct siRNA SR414119
PANX1 Prenatal exposure to inflammatory conditions increases Cx43 and Panx1 unopposed channel opening and activation of astrocytes in the offspring effect on neuronal survival Glia, 2015 Jun siRNA SR414119
PANX1 Pannexin 1 Channels Mediate the Release of ATP into the Lumen of the Rat Urinary Bladder J. Physiol. (Lond.), 2015 Jan siRNA SR513786
PANX1 Astrocytes inhibit nitric oxide-dependent Ca(2+) dynamics in activated microglia: Involvement of ATP released via pannexin 1 channels Glia. 2013 Dec;61(12):2023-37, 2013 Oct siRNA SR513786
PAPPA MiR-490-3p modulates the proliferation of vascular smooth muscle cells induced by ox-LDL through targeting PAPP-A Cardiovasc Res, Jul 2013; 10.1093/cvr/cvt172., 2013 Jul siRNA SR303354
PAPPA MiR-490-3p modulates proliferation of vascular smooth muscle cells induced by ox-LDL through targeting PAPP-A Cardiovascular Research Advance Access, 2013 Jul siRNA SR303354
PARK7 The Parkinsonism-associated protein DJ-1/Park7 prevents glycation damage in human keratinocyte Biochem. Biophys. Res. Commun., 2016 Mar siRNA SR307752
PARP1 PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells Cancer biotherapy & radiopharmaceuticals, 2021 May siRNA SR319280
PAX3 c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR303360
PAX3 FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR303360
PAX4 PAR2 regulates regeneration, transdifferentiation, and death Cell Death Dis, 2016 Nov siRNA SR303361
PAX6 ADAR1-mediated regulation of melanoma invasion Nat Commun, 2018 May siRNA SR303363
PCNA Proliferating cell nuclear antigen promotes cell proliferation and tumorigenesis by up-regulating STAT3 in non-small cell lung cancer Biomed. Pharmacother., 2018 May siRNA SR303386
PCSK5 Extracellular processing of lysyl oxidase-like 2 and its effect on amine oxidase activity Biochemistry, 2018 Nov siRNA SR303392
PCSK6 Extracellular processing of lysyl oxidase-like 2 and its effect on amine oxidase activity Biochemistry, 2018 Nov siRNA SR303337
PCSK6 PACE4 Proteolytically Processes LOXL2 with little impact on its catalytic activity J. Biol. Chem., 2017 Nov siRNA SR303337
PCSK9 (Pro)renin receptor mediates albumin-induced cellular responses: role of site-1 protease-derived soluble (pro)renin receptor in renal epithelial cells American Journal of Physiology - Cell Physiology, 2018 Dec siRNA SR316837
PCYT1A MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma Blood Cancer J, 2017 Jul siRNA SR303397
PCYT1A Hepatitis C virus induced changes in cellular lipids-identifying novel host antiviral drug target Thesis, 2014 Aug siRNA SR303397
PD-L1 Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition J. Clin. Invest., 2016 Aug siRNA SC115168
PDCD10 miRNA-24-3p promotes cell proliferation and regulates chemosensitivity in head and neck squamous cell carcinoma by targeting CHD5 Future Oncol, 2016 Aug siRNA SR307707
PDCD10 MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10 J. Cell. Mol. Med., 2015 Dec siRNA SR307707
PDE1B Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways Cell Rep, 2016 May siRNA SR303418
PDE3B Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology Nat Commun, 2019 Sep siRNA SR422062
PDE3B Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology bioRxiv, 2018 Oct siRNA SR422062
Pde5a Inhibition of phosphodiesterase 5A by tadalafil improves SIRT1 expression and activity in insulin-resistant podocytes. Cellular signalling, 2023 Mar siRNA SR506246
PDGFD Molecular mechanisms of coronary artery disease risk at the PDGFD locus Nature Communications, 2023 Feb siRNA SR312885
Pdgfd Role of PDGF-D and PDGFR-ß in neuroinflammation in experimental ICH mice model Exp. Neurol., 2016 Jun siRNA SR407408
Pdgfrb PDGFR-β modulates vascular smooth muscle cell phenotype via IRF-9/SIRT-1/NF-κB pathway in subarachnoid hemorrhage rats J. Cereb. Blood Flow Metab., 2018 Jan siRNA SR510985
Pdgfrb Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice J. Cereb. Blood Flow Metab., 2016 Nov siRNA SR422058
Pdgfrb Platelet-Derived Growth Factor Receptor-β Regulates Vascular Smooth Muscle Cell Phenotypic Transformation and Neuroinflammation After Intracerebral Hemorrhage in Mice Crit. Care Med., 2016 Jun siRNA SR422058
PDIA2 Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes Theranostics, 2019 Apr siRNA SR312088
PDLIM2 Klotho ameliorates cyclosporine A-induced nephropathy via PDLIM2/NF-kB p65 signaling pathway Biochem. Biophys. Res. Commun, 2017 Mar siRNA SR411767
Pdlim3 Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma. Oncogene, 2022 Dec siRNA SR410257
PDZRN3 PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability Sci. Signal, 2017 Jan siRNA SR307944
PDZRN3 Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity signaling pathway Mol. Biol. Cell, 2016 Jan siRNA SR307944
PDZRN3 The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling Nat Commun, 2014 Sep siRNA SR307944
PECAM1 Syndecan-4 controls lymphatic vasculature remodeling during embryonic development Development, 2016 Oct siRNA SR303439
PELI3 TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of Caspase-8/NLRP3 after middle cerebral artery occlusion in rats Research Square, 2020 Dec siRNA SR512499
PEMT Hepatitis C virus induced changes in cellular lipids-identifying novel host antiviral drug target Thesis, 2014 Aug siRNA SR307049
PFKFB3 Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR Cell, 2019 Apr siRNA SR416726
PFKFB3 GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo J. Nucl. Med., 2016 Sep siRNA SR416726
PFKFB3 Bioenergetic Mechanisms in Astrocytes May Contribute to Amyloid Plaque Deposition and Toxicity The Journal of Biological Chemistry, 2015 May siRNA SR321285
PFKFB3 Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity JBC Papers in Press, 2015 Mar siRNA SR303464
PGR Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation Laboratory investigation; a journal of technical methods and pathology, 2021 Apr siRNA SR510584
PGRMC1 Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation Laboratory investigation; a journal of technical methods and pathology, 2021 Apr siRNA SR503385
PGRMC1 Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling Br. J. Cancer, 2020 Jul siRNA SR323253
PHB Prohibitin 1/2 mediates Dengue-3 entry into human neuroblastoma (SH-SY5Y) and microglia (CHME-3) cells J. Biomed. Sci., 2020 Apr siRNA SR303488
PHB The Role and Regulation of Mitochondrial Dynamics in Cisplatin Resistance in Human Gynecologic Cancer Cells Thesis, 2015 Jun siRNA SR303488
PHB2 Prohibitin 1/2 mediates Dengue-3 entry into human neuroblastoma (SH-SY5Y) and microglia (CHME-3) cells J. Biomed. Sci., 2020 Apr siRNA SR307765