shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
NLRP3 Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death Sci Rep, 2016 May shRNA TG305382
Nlrp3 Inhibition of Hyperhomocysteinemia-Induced Inflammasome Activation and Glomerular Sclerosis by NLRP3 Gene Deletion Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016 May shRNA TG510752
NLRP3 Instigation of endothelial Nlrp3 inflammasome by adipokine visfatin promotes inter-endothelial junction disruption: role of HMGB1 J. Cell. Mol. Med., 2015 Aug shRNA TG510752
NLRP3 Gene silencing of NLRP3 protects against the sepsis-induced hyper -bileacidemia in a rat model Clin. Exp. Immunol., 2014 Sep shRNA TG305382
NLRP3 Measles Virus V Protein Inhibits NLRP3 Inflammasome-Mediated Interleukin-1ß Secretion J. Virol., Dec 2011; 85: 13019 - 13026., 2011 Dec shRNA TR305382
NLRP3 Francisella tularensis Reveals a Disparity between Human and Mouse NLRP3 Inflammasome Activation J. Biol. Chem., Nov 2011; 286: 39033 - 39042., 2011 Nov shRNA TR305382
NLRX1 Nlrx1 regulates neuronal cell death Mol Brain, 2014 Dec shRNA TG515304
NME2 Promoter-proximal transcription factor binding is transcriptionally active when coupled with nucleosome repositioning in immediate vicinity Nucleic Acids Res. July 2014, 2014 Jul shRNA TR311160
NMRK2 SNARE-dependent interaction of Src, EGF receptor and β1 integrin regulates invadopodium formation and tumour cell invasion J. Cell. Sci., Feb 2014., 2014 Feb shRNA TF315677
NMS Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration FASEB J., 2018 Oct shRNA TG311156
Nod1 Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses Cancer research, 2016 Jun shRNA TL511305
NOD1 Cdx2 expression and intestinal metaplasia induced by H. pylori infection of gastric cells is regulated by NOD1-mediated innate immune responses Cancer Res., 2016 Jan shRNA TG511305
NODAL Cancer-associated fibroblasts promote PD-L1 expression in mice cancer cells via secreting CXCL5 Int. J. Cancer, 2019 Mar shRNA TG501492
NODAL Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo Am J Cancer Res, 2015 Aug shRNA TG501492
NODAL Nodal promotes the generation of M2-like macrophages and downregulates the expression of IL-12 Eur J Immunol. 2013 Oct 1., 2013 Oct shRNA TG302929
NOLC1 Tissue-specific Gene Targeting by the Multiprotein Mammalian DREAM Complex J. Biol. Chem., Aug 2011; 286: 27867 - 27871., 2011 Aug shRNA TR311147
Non-effective 29-mer Scrambled shRNA The role of the ATPase inhibitor factor 1 (IF1) in cancer cells adaptation to hypoxia and anoxia Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2017 Oct shRNA TR30013
Non-effective Control Evaluation of tryptophan-aspartic acid repeat-containing protein 34 as a novel tumor-suppressor molecule in human oral cancer Biochem. Biophys. Res. Commun., 2017 Dec shRNA TR30012
Non-Effective GFP RhoC regulates actin remodeling to form phagosomes during FcγR-mediated phagocytosis J. Cell. Sci.2017, 2017 Nov shRNA TR30008
NONO p54nrb/NONO Regulates cAMP-dependent Glucocorticoid Production by Modulating Phosphodiesterase mRNA Splicing and Degradation Mol. Cell. Biol., 2015 Jan shRNA TG311143
NOS1 Sarcolemmal loss of active nNOS (Nos1) is an oxidative stress-dependent, early event driving disuse atrophy J. Pathol., 2018 Jul shRNA TG711710
Nos1ap Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. Science advances, 2022 Apr shRNA TL511126
NOS2 Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania PeerJ, 2018 Apr shRNA TR709254
Nos2 Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype Nat. Immunol., 2016 Sep shRNA TR512302
NOS2 Apoptotic Programs Are Determined during Lineage Commitment of CD4+ T Effectors: Selective Regulation of T Effector-Memory Apoptosis by Inducible Nitric Oxide Synthase J. Immunol., Jan 2013; 190: 97 - 105., 2013 Jan shRNA TG512302
Notch1 Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells Elife, 2016 Jun shRNA TG513589
NOTCH1 Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome PLoS ONE July 2014, 2014 Jul shRNA TR302916
NOTCH2 NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cells Oncol. Rep., 2015 Oct shRNA TR302915
NOTCH2 Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo Mol Med Rep, 2014 Dec shRNA TG302915
Notch2 Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo Molecular Medicine Reports, 2014 Dec shRNA TL711020
Notch3 Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord J. Cell. Mol. Med., 2014 Aug shRNA TR515445
NOVA1 Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC- DLBCL cells in vitro and in vivo Molecular cancer therapeutics, 2013 May shRNA TF311136
NOX1 Molecular interplay between NOX1 and autophagy in cadmium-induced prostate carcinogenesis. Free radical biology & medicine, 2023 Mar shRNA TG311135
NOX1 Nox1 promotes colon cancer cell metastasis via activation of the ADAM17 pathway Eur Rev Med Pharmacol Sci, 2016 Nov shRNA TF311135
Nox1 NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015 Jun shRNA TL514988
NOX1 NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015 Jun shRNA TL311135
NOX3 Targeting tyrosine kinase inhibitor resistant non-small-cell lung cancer by inducing EGFR degradation via methionine 790 oxidation Antioxid. Redox Signal., 2015 Nov shRNA TG302912
NOX4 Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR Methods in molecular biology (Clifton, N.J.), 2021 May shRNA TG302911
NOXA1 Obatoclax Interacts Synergistically with the Irreversible Proteasome Inhibitor Carfilzomib in GC- and ABC-DLBCL Cells In Vitro and In Vivo Mol. Cancer Ther., May 2012; 11: 1122 - 1132., 2012 May shRNA TR311134
NP100005 NRP-1 expression is strongly associated with the progression of pituitary adenomas Oncol. Rep., 2014 Aug shRNA TR30019
NP100041 Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells Br. J. Cancer July 2014, 2014 Jul shRNA TR20003
Npr3 NPR3 protects cardiomyocytes from apoptosis through inhibition of cytosolic BRCA1 and TNF-a Cell Cycle, 2016 Aug shRNA TR709485
Nprl3 DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons Neurobiol. Dis., 2018 Feb shRNA TG501301
NQO2 Control of stability of cyclin D1 by quinone reductase 2 in CWR22Rv1 prostate cancer cells Carcinogenesis, Mar 2012; 33: 670 - 677., 2012 Mar shRNA TR311108
Nr1h3 Regulation of Insulin Resistance and Adiponectin Signaling in Adipose Tissue by Liver X Receptor Activation Highlights a Cross-Talk with PPAR? PLoS ONE, 2014 Jun shRNA TG502381
NR1H4 Farnesoid X receptor as marker of osteotropism of breast cancers through its role in the osteomimetism of tumor cells BMC Cancer, 2020 Jul shRNA TG320627
NR1H4 Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling PLoS ONE, 2015 Jul shRNA TG320627
NR1I2 Effects of silenced PAR-2 on cell proliferation, invasion and metastasis of esophageal cancer Oncology Letters, 2017 Aug shRNA TG320596
NR1I2 Pregnane X Receptor As a Therapeutic Target to Inhibit Androgen Activity Endocrinology, Oct 2010; 10.1210/en.2010-0708, 2010 Oct shRNA TR320596
NR2F2 Oncogenic KRAS signaling activates mTORC1 through COUP-TFII-mediated lactate production EMBO Rep., 2019 Apr shRNA TR320548