siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PHB2 Mitoquinone attenuates blood-brain barrier disruption through Nrf2/PHB2/OPA1 pathway after subarachnoid hemorrhage in rats Exp. Neurol., 2019 Feb siRNA SR307765
PHB2 Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone J. Biol. Chem., 2018 May siRNA SR307765
PHF8 c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer Oncotarget, 2016 Nov siRNA SR308029
PHLPP1 Role of PHLPP1 in inflammation response: Its loss contributes to gliomas development and progression Int. Immunopharmacol., 2016 Mar siRNA SR308119
PIAS1 Stress-induced nuclear condensation of NELF drives transcriptional downregulation Molecular cell, 2021 Jan siRNA SR305620
PIAS4 Stress-induced nuclear condensation of NELF drives transcriptional downregulation Molecular cell, 2021 Jan siRNA SR309861
PIK3C2A A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits Cell, 2018 Jul siRNA SR303516
PIK3C2A PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: Modulation by PTEN J. Clin. Endocrinol. Metab., 2014 May siRNA SR303516
Pik3c2b PI3 kinases p110a and PI3K-C2ß negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets Molecular Metabolism, 2016 May siRNA SR423087
PIK3C3 Insulin activation of vacuolar protein sorting 34 mediates localized phosphatidylinositol 3-phosphate production at lamellipodia and activation of mTOR/S6K1 Cell. Signal., 2014 Feb siRNA SR303519
Pik3ca Abl-mediated PI3K activation regulates macrophage podosome formation. Journal of cell science, 2021 Jun siRNA SR421939
PIK3CA PI3K-p110δ contributes to antibody responses by macrophages in chronic lymphocytic leukemia Leukemia, 2019 Aug siRNA SR303520
Pik3cb Abl-mediated PI3K activation regulates macrophage podosome formation. Journal of cell science, 2021 Jun siRNA SR421863
PIK3CB PI3K-p110δ contributes to antibody responses by macrophages in chronic lymphocytic leukemia Leukemia, 2019 Aug siRNA SR303521
PIM1 Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival Neuro-oncology, 2014 Aug siRNA SR303522
PINK1 Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue Cell metabolism, 2022 Apr siRNA SR324912
PINK1 Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson\'s disease models Aging, 2021 Apr siRNA SR324912
PINK1 Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism Sci Rep, 2018 Jun siRNA SR417710
PINK1 SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation Sci Rep, 2018 Jan siRNA SR312201
PINK1 Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD(+)/SIRT1 Reduction Cell, 2014 May siRNA SR312201
PIP Peripheral immune tolerance by prolactin-induced protein originated from human invariant natural killer T cells Bioengineered, 2021 Dec siRNA SR303531
PIP Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance J. Leukoc. Biol., 2016 Nov siRNA SR303531
PITX2 PITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathy Stem Cell Reports, 2023 Mar siRNA SR321325
PKD2 The tumor promoter-activated protein kinase Cs are a system for regulating filopodia Cytoskeleton (Hoboken) 2017, 2017 May siRNA SR421480
PKD2L1 TRP channels in brown and white adipogenesis from human progenitors: new therapeutic targets and the caveats associated with the common antibiotic, streptomycin FASEB J., 2017 Apr siRNA SR305958
PLA2R1 Diverse effects of phospholipase A2 receptor expression on LNCaP and PC-3 prostate cancer cell growth in vitro and in vivo Oncotarget, 2018 Nov siRNA SR307882
PLAC1 Plac1 promotes nasopharyngeal carcinoma cells proliferation, migration and invasion via Furin/NICD/PTEN pathway Tissue & cell, 2021 Jan siRNA SR307335
PLAC1 Declined placental PLAC1 expression is involved in preeclampsia Medicine (Baltimore) 2019, 2019 Nov siRNA SR307335
PLCG1 MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration Frontiers in immunology, 2020 Dec siRNA SR321342
PLCG1 MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration Frontiers in immunology, 2020 Dec siRNA SR422621
PLD2 Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment Oncogene, 2018 Oct siRNA SR421360
PLEKHG3 PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front Proc. Natl. Acad. Sci. U.S.A., 2016 Aug siRNA SR308671
PLIN2 Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism Oncotarget, 2016 Oct siRNA SR300083
PLK4 Role for polo-like kinase 4 in mediation of cytokinesis Proc. Natl. Acad. Sci. U.S.A., 2019 May siRNA SR307314
PLOD2 Lysyl hydroxylases are transcription targets for GATA3 driving lung cancer cell metastasis Sci Rep, 2018 Aug siRNA SR303576
PLOD3 Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the fibroblast cell surface by Lysyl Hydroxylase-3 (LH3) triggers TGF-ß activation and fibroblast differentiation J. Biol. Chem., 2015 Mar siRNA SR305927
Plxdc2 Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF eLife, 2014 Dec siRNA SR416812
PLXNB3 Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells Journal of Proteome Research, 2022 Aug siRNA SR303587
PML Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function mBio, 2020 Jun siRNA SR321357
PNPLA8 SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy Sci Rep, 2016 Oct siRNA SR309408
POLA1 DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA PLoS Pathog., 2019 Apr siRNA SR303612
POLA2 DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA PLoS Pathog., 2019 Apr siRNA SR308429
POLDIP2 Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model CNS Neurosci Ther, 2020 Aug siRNA SR412409
POLR1G Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer Nat Commun, 2016 Feb siRNA SR307394
POLR3A Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA Proc. Natl. Acad. Sci. U.S.A., 2016 Nov siRNA SR307620
PON1 Resveratrol exhibits an effect on attenuating retina inflammatory condition and damage of diabetic retinopathy via PON1 Exp. Eye Res., 2018 Nov siRNA SR515335
POR The neurosteroid pregnenolone is synthesized by a mitochondrial P450 enzyme other than CYP11A1 in human glial cells The Journal of Biological Chemistry, 2022 Jun siRNA SR303637
PORCN Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling Cell, 2019 Jan siRNA SR324902
Positive Control Promoting effects of MiR-135b on human multiple myeloma cells via regulation of the Wnt/β-catenin/Versican signaling pathway Cytokine, 2021 Mar siRNA SR30002
Positive Control Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1 Inflammation, 2020 Oct siRNA SR30002