shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
NR4A1 Dendrogenin A drives LXR to trigger lethal autophagy in cancers Nat Commun, 2017 Dec shRNA TG514239
NR4A1 Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog PLoS ONE e94732 9 4. April 2014, 2014 Apr shRNA TG320381
NR4A3 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell Rep, 2019 Jul shRNA TF501493
Nr4a3 Dendrogenin A drives LXR to trigger lethal autophagy in cancers Nat Commun, 2017 Dec shRNA TF501493
NR5A1 cAMP-stimulated transcription of DGK{theta} requires steroidogenic factor 1 and sterol regulatory element binding protein 1 J. Lipid Res., Aug 2013; 54: 2121 - 2132., 2013 Aug shRNA TG311103
NRAS The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation Cell Rep, 2019 Nov shRNA TR712458
NRF1 Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells Toxicol. Appl. Pharmacol., 2016 Jul shRNA TR311098
NRIP1 New Target Genes in Endometrial Tumors Show a Role for the Estrogen-Receptor Pathway in Microsatellite Unstable Cancers Hum. Mutat., 2014 Sep shRNA TG311094
NRP1 Sema3a-Nrp1 Signaling Mediates Fast-Twitch Myofiber Specificity of Tw2+ Cells Dev. Cell, 2019 Aug shRNA TG513573
NRP1 Neuropilin1 is an important niche component and exerts context-dependent effects on hematopoietic stem cells Stem Cells Dev., 2016 Sep shRNA TR513573
NRP1 NRP-1 expression is strongly associated with the progression of pituitary adenomas Oncol. Rep., 2014 Aug shRNA TR311093
NRP1 The Plexin-A1 Receptor Activates Vascular Endothelial Growth Factor-Receptor 2 and Nuclear Factor-B to Mediate Survival and Anchorage-Independent Growth of Malignant Mesothelioma Cells Cancer Res., Feb 2009; 69: 1485 - 1493, 2009 Feb shRNA TR311093
Nsd2 The Histone Methyltransferase MMSET Regulates Class Switch Recombination J. Immunol., Jan 2013; 190: 756 - 763., 2013 Jan shRNA TF517851
NSUN5 RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma. Molecular oncology, 2023 Apr shRNA TL302876
Nt5e Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis PNAS, Jan 2010; 107: 1547 - 1552, 2010 Jan shRNA TR515992
Ntf4 PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise Cell metabolism, 2018 May shRNA TF709774
NTRK1 Safrole oxide induces human umbilical vein endothelial cell transdifferentiation to 5-hydroxytryptaminergic neuron-like cells through tropomyosin receptor kinase A/cyclooxygenase 2/nuclear factor-kappa B/interleukin 8 signaling. The international journal of biochemistry & cell biology, 2011 Dec shRNA TR320435
NTRK1 Effect of Brain- and Tumor-Derived Connective Tissue Growth Factor on Glioma Invasion J Natl Cancer Inst, Aug 2011; 103: 1162 - 1178., 2011 Aug shRNA TR320435
Ntrk2 BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization J. Pathol., 2014 Nov shRNA TR510739
NTRK2 TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma Oncogene (18 January 2010) doi:10.1038/onc.2009.486 Original Article, 2010 Jan shRNA TR320436
NUCB2 Nucleobindin-2 is a positive regulator for insulin-stimulated glucose transporter 4 translocation in fenofibrate treated E11 podocytes [Rapid Communication] Endocr. J., 2014 Sep shRNA TR502933
Nucb2 Nucleobindin-2 Is a Positive Modulator of EGF-Dependent Signals Leading to Enhancement of Cell Growth and Suppression of Adipocyte Differentiation Endocrinology, Jul 2012; 153: 3308 - 3319., 2012 Jul shRNA TR502933
Nudt1 MTH1 favors mesothelioma progression and mediates paracrine rescue of bystander endothelium from oxidative damage JCI Insight, 2020 Jun shRNA TL501390
NUMA1 The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair Nucleic Acids Res., 2019 Apr shRNA TR311065
NUMB NUMB and NUMBL differences in gene regulation Oncotarget, 2018 Feb shRNA TR311064
NUMB The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB Clin. Cancer Res, 2017 Feb shRNA TR311064
Numb Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy Oncotarget, 2016 Sep shRNA TR311064
NUMB Uric acid crystal could inhibit Numb-induced URAT1 lysosome degradation in uric acid nephropathy J. Physiol. Biochem., 2015 Mar shRNA TR311064
NUMBL NUMB and NUMBL differences in gene regulation Oncotarget, 2018 Feb shRNA TR311063
NumbL Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy Oncotarget, 2016 Sep shRNA TR311063
ODAM ODAM inhibits RhoA-dependent invasion in breast cancer Cell Biochem. Funct., 2015 Sep shRNA TG307066
OGA Epithelial mesenchymal transition induces aberrant glycosylation through hexosamine biosynthetic pathway activation J. Biol. Chem., 2016 Apr shRNA TG315637
OGT The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis Nat Commun, 2017 May shRNA TG302811
OGT Epithelial mesenchymal transition induces aberrant glycosylation through hexosamine biosynthetic pathway activation J. Biol. Chem., 2016 Apr shRNA TG302811
OLR1 Lectin-like oxidized LDL receptor-1 expresses in mouse bone marrow-derived mesenchymal stem cells and stimulates their proliferation. Experimental cell research, 2013 May shRNA TL311028
OMA1 Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells Sci Rep, 2019 Oct shRNA TR302802
OMA1 OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury Am. J. Physiol. Renal Physiol. . March 2014, 2014 Mar shRNA TR302802
OR51E1 Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line The Journal of biological chemistry, 2021 Feb shRNA TR302775
ORAI1 Arachidonic acid-induced Ca2+entry and migration in a neuroendocrine cancer cell line Cancer Cell Int., 2018 Mar shRNA TF301009
ORAI1 Molecular mechanisms of spontaneous and directed mast cell motility J. Leukoc. Biol., Nov 2012; 92: 1029 - 1041., 2012 Nov shRNA TG301009
ORAI1 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR301009
Orai1 Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line J. Immunol., Feb 2008; 180: 2233 - 2239., 2008 Feb shRNA TR301009
ORAI2 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR301008
ORAI3 Arachidonic acid-induced Ca2+entry and migration in a neuroendocrine cancer cell line Cancer Cell Int., 2018 Mar shRNA TF307587
ORAI3 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR307587
OSBPL2 Oxysterol-related-binding-protein related Protein-2 (ORP2) regulates cortisol biosynthesis and cholesterol homeostasis Mol. Cell. Endocrinol., 2016 Mar shRNA TG310662
OSBPL9 Odd-skipped related 1 is a novel tumour suppressor gene and a potential prognostic biomarker in gastric cancer The Journal of Pathology, 2014 Nov shRNA TG302749
OSR1 Odd-skipped related 1 is a novel tumor suppressor gene and a potential prognostic biomarker in gastric cancer J. Pathol., 2014 Jun shRNA TG302745
P4HB Inhibition of prolyl 4-hydroxylase, beta polypeptide (P4HB) attenuates temozolomide resistance in malignant glioma via the endoplasmic reticulum stress response (ERSR) pathways Neuro Oncology, May 2013; 15: 562 - 577., 2013 May shRNA TR310639
P4HB Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure Blood, Aug 2010; 116: 993 - 1001, 2010 Aug shRNA TR310639