siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Positive Control The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome J. Cell. Sci., 2018 Aug siRNA SR30003
POTEA Cell membrane-bound CD200 signals both via an extracellular domain and following nuclear translocation of a cytoplasmic fragment Leuk. Res., 2018 Apr siRNA SR317504
POTEH The C-terminal common to group 3 POTES (CtG3P): a newly discovered nucleolar marker associated with malignant progression and metastasis American Journal of Cancer Research, 2013 Jun siRNA SR308469
POU5F1 Female sex hormones activate HERV-K through the OCT4 transcription factor in T47D breast cancer cells AIDS Res. Hum. Retroviruses, 2018 Dec siRNA SR303649
POU5F1 Integrated regulation of class II human endogenous retroviruses in a breast cancer cell line The Proceedings of the International Conference on Creationism, 2018 Aug siRNA SR303649
PPARG PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions Nature communications, 2021 May siRNA SR321378
PPARG Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells Biochim Biophys Acta Gene Regul Mech, 2020 Jan siRNA SR500194
PPARG Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARγ-Akt signaling pathway at the early stage of carcinogenesis Oncotarget, 2017 Nov siRNA SR303655
PPARGC1A Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action Proc. Natl. Acad. Sci. U.S.A., 2020 Aug siRNA SR427524
PPARGC1A MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α Biochim. Biophys. Acta, 2018 May siRNA SR420231
PPARGC1A Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes Cell, 2017 Mar siRNA SR420231
PPARGC1A The neuroprotective role of metformin in advanced glycation end product treated human neural stem cells is AMPK-dependent Biochim. Biophys. Acta, 2015 Jan siRNA SR420231
Ppargc1a Rosiglitazone promotes neurite outgrowth and mitochondrial function in N2A cells via PPARgamma pathway Mitochondrion Dec 2013., 2013 Dec siRNA SR420231
PPFIA1 Characterization of the polarized endothelial secretome FASEB J., 2019 Aug siRNA SR305572
PPIC Systems analysis identifies miR-29b regulation of invasiveness in melanoma Mol. Cancer, 2016 Nov siRNA SR303664
PPP1CA CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation J. Cell Biol., 2019 Feb siRNA SR303671
PPP1CA MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability Nat Commun, 2018 Aug siRNA SR303671
PPP1CB CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation J. Cell Biol., 2019 Feb siRNA SR303672
PPP1CB MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability Nat Commun, 2018 Aug siRNA SR303672
PPP1CC CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation J. Cell Biol., 2019 Feb siRNA SR410723
PPP1CC MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability Nature Communications, 2018 Aug siRNA SR303673
PPP2CA Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity Sci Adv, 2018 Aug siRNA SR409313
PPP2CA PP2AC Level Determines Differential Programing of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer EBioMedicine, 2015 Nov siRNA SR303682
PPP2R2C A conserved long-distance telomeric silencing mechanism suppresses mTOR signaling in aging human fibroblasts Science Advances, 2022 Aug siRNA SR303688
PPP3CA GNAQ Negatively Regulates Antiviral Innate Immune Responses in a Calcineurin-Dependent Manner J. Immunol., 2019 Jul siRNA SR416619
PPP3CA Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity Sci Adv, 2018 Aug siRNA SR416619
PPP5C Structural and functional basis of protein phosphatase 5 substrate specificity Proc. Natl. Acad. Sci. U.S.A., 2016 Aug siRNA SR303702
PPT1 PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma JCI Insight, 2020 Sep siRNA SR409088
PPTC7 The mitochondrial phosphatase PPTC7 orchestrates mitochondrial metabolism regulating coenzyme Q10 biosynthesis Biochim Biophys Acta Bioenerg, 2018 Sep siRNA SR315995
PRDM1 NonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells Front. Immunol., 2020 Jul siRNA SR300437
PRDM1 Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer Cells, 2019 Sep siRNA SR300437
Prdm1 Increased cathepsin S in Prdm1-/- dendritic cells alters the TFH cell repertoire and contributes to lupus Nat. Immunol., 2017 Sep siRNA SR420429
PRDM1 Cellular differentiation regulator BLIMP1 induces Epstein-Barr virus lytic reactivation in epithelial and B cells by activating transcription from both the R and Z promoters J. Viro, 2014 Nov siRNA SR300437
PRDM14 Geometric regulation of histone state directs melanoma reprogramming Commun Biol, 2020 Jul siRNA SR417406
PRDX1 Peroxiredoxin 1, a novel HBx-interacting protein, interacts with Exosc5 and negatively regulates HBV propagation through degradation of HBV RNA J. Virol., 2018 Dec siRNA SR303343
PRKAA1 The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting EMBO Mol Med, 2018 May siRNA SR417172
PRKAA1 Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway Oncol Lett, 2016 May siRNA SR303721
PRKAA1 LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress Nat. Cell Biol., 2016 Apr siRNA SR303721
PRKAA2 LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress Nat. Cell Biol., 2016 Apr siRNA SR303722
PRKACA Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism Sci Signal, 2018 Apr siRNA SR411864
PRKACA Regulation of Mitochondrial poly (ADP-ribose) Polymerase Activation by the ß-adrenoceptor/cAMP/Protein Kinase A Axis During Oxidative Stress Molecular PHARMACOLOGY July 2014, 2014 Jul siRNA SR303725
PRKAR2B Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts Oncotarget, 2018 Jan siRNA SR303734
PRKCA The Syndecan-4/Protein Kinase Ca Pathway Mediates Prostaglandin E2-induced Extracellular Regulated Kinase (ERK) Activation in Endothelial Cells and Angiogenesis in Vivo J. Biol. Chem., May 2013; 288: 12712 - 12721., 2013 May siRNA SR303735
PRKCA Protein Kinases D2 and D3 Are Novel Growth Regulators in HCC1806 Triple-negative Breast Cancer Cells Anticancer Res, Feb 2013; 33: 393 - 399., 2013 Feb siRNA SR303735
Prkce Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation Nature Communications, 2022 Dec siRNA SR427452
PRKCE Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease J. Immunol., 2015 Oct siRNA SR303738
PRKCI Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion Cell adhesion & migration, 2021 Dec siRNA SR321426
PRKCI The interruption of atypical PKC signaling and Temozolomide combination therapy against glioblastoma Cellular Signalling, 2020 Nov siRNA SR321426
PRKCI c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR321426
PRKCI The modulation of actin dynamics via atypical Protein Kinase-C activated Cofilin regulates metastasis of colorectal cancer cells Cell Adh Migr, 2019 Dec siRNA SR321426