shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PABPC4 The Cytoplasmic poly(A) Binding Protein, PABPC4, Serves a Critical Role in Erythroid Differentiation Mol. Cell. Biol., Jan 2014., 2014 Jan shRNA TG510913
Padi4 Citrullination regulates pluripotency and histone H1 binding to chromatin Nature, Feb 2014., 2014 Feb shRNA TF501611
PAF1 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Oct 2012; 209: 2099 - 2111., 2012 Oct shRNA TG302706
PAF1 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Sep 2012; 10.1084/jem.20112145., 2012 Sep shRNA TR302706
PAK1 Modulation of store-operated calcium entry and nascent adhesion by p21-activated kinase 1 Exp. Mol. Med., 2018 May shRNA TF320442
PAK1 Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis Cell Rep, 2014 Nov shRNA TG501572
PAK1 P21 Activated Kinase-1 (Pak1) Promotes Prostate Tumor Growth and Microinvasion via Inhibition of Transforming Growth Factor ß Expression and Enhanced Matrix Metalloproteinase 9 Secretion J. Biol. Chem., Feb 2013; 288: 3025 - 3035., 2013 Feb shRNA TG320442
PAK2 Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells Cancers (Basel) 2019, 2019 Oct shRNA TF506650
PAK4 p21-Activated kinase 4 promotes prostate cancer progression through CREB Oncogene doi:10.1038/onc.2012.255, 2012 Jun shRNA TR320637
PAK4 p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients PNAS, Oct 2010; 107: 18622 - 18627, 2010 Oct shRNA TR320637
PAK6 P21 Activated Kinase-1 (Pak1) Promotes Prostate Tumor Growth and Microinvasion via Inhibition of Transforming Growth Factor ß Expression and Enhanced Matrix Metalloproteinase 9 Secretion J. Biol. Chem., Feb 2013; 288: 3025 - 3035., 2013 Feb shRNA TF320717
PALB2 PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2 Mol. Cancer Res., Jul 2009; 7: 1110 - 1118., 2009 Jul shRNA TR307284
Pam16 Magmas, a Gene Newly Identified as Overexpressed in Human and Mouse ACTH-Secreting Pituitary Adenomas, Protects Pituitary Cells from Apoptotic Stimuli Endocrinology, Oct 2010; 151: 4635 - 4642, 2010 Oct shRNA TR513987
PANX1 High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer Cancers, 2022 Jul shRNA TF302694
PANX1 Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism The Journal of biological chemistry, 2021 Feb shRNA TR302694
PANX1 Pannexin 1 binds β-catenin to modulate melanoma cell growth and metabolism The Journal of Biological Chemistry, 2021 Feb shRNA TL302694
PANX1 Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells Cancers (Basel) 2019, 2019 Jan shRNA TR302694
PANX1 Loss of Pannexin 1 Attenuates Melanoma Progression by Reversion to a Melanocytic Phenotype J. Biol. Chem., Aug 2012; 287: 29184 - 29193., 2012 Aug shRNA TR302694
PANX1 The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes J. Biol. Chem., Jul 2009; 284: 18143 - 18151, 2009 Jul shRNA TR302694
PANX3 Pannexin 3 regulates skin development via Epiprofin Scientific Reports, 2021 Dec shRNA TG302692
PANX3 Characterization and Function of the~ 70 kDa Immunoreactive Species of Pannexin3 in Rhabdomyosarcomas Thesis, 2015 Jan shRNA TF302692
Panx3 Pannexin 1 and Pannexin 3 Channels Regulate Skeletal Muscle Myoblast Proliferation and Differentiation J. Biol. Chem., 2014 Sep shRNA TF302692
PARD3 Elevated expression of Par3 promotes prostate cancer metastasis by forming a Par3/aPKC/KIBRA complex and inactivating the hippo pathway J. Exp. Clin. Cancer Res., 2017 Oct shRNA TR302678
Parp1 Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage International Journal of Molecular Sciences, 2022 Jul shRNA TL509117
PARP1 Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 PLoS Pathog., 2018 Nov shRNA TR315488
PARP1 The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1 PLoS Genet., 2016 Sep shRNA TG315488
PARP1 Poly(ADP-ribose) Contributes to an Association between Poly(ADP-ribose) Polymerase-1 and Xeroderma Pigmentosum Complementation Group A in Nucleotide Excision Repair J. Biol. Chem., Nov 2012; 287: 39824 - 39833., 2012 Nov shRNA TG315488
PARP1 Thrombomodulin Is Silenced in Malignant Mesothelioma by a Poly(ADP-ribose) Polymerase-1-mediated Epigenetic Mechanism J. Biol. Chem., Jun 2011; 286: 19478 - 19488, 2011 Jun shRNA TR315488
PARP1 Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression Blood, Mar 2011; 117: 2891 - 2900, 2011 Mar shRNA TR315488
ParvB Expression of parvin-ß is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract British Journal of Cancer 103, 852-860 (24 August 2010) doi:10.1038/sj.bjc.6605835 Full Paper, 2010 Aug shRNA TR310602
PATE4 shRNA mediated ablation of prostate and testis expressed (Pate) messenger RNA results in impaired sperm function and fertility Andrology, 2017 Feb shRNA TG707288
PAX5 PAX5 is the transcriptional activator of mucolipin-2 (MCOLN2) gene Gene, 2014 Nov shRNA TG302663
PAX6 Pax6 Regulates the Expression of Dkk3 in Murine and Human Cell Lines, and Altered Responses to Wnt Signaling Are Shown in FlpIn-3T3 Cells Stably Expressing Either the Pax6 or the Pax6(5a) Isoform PLoS ONE July 2014, 2014 Jul shRNA TG310597
Pbx3 PBX3 is an important cofactor of HOXA9 in leukemogenesis Blood, Feb 2013; 121: 1422 - 1431., 2013 Feb shRNA TG310590
PCBP1 PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing Nucleic Acids Res., 2017 Dec shRNA TG310588
PCBP1 PCBP1 suppresses the translation of metastasis-associated PRL-3 phosphatase. Cancer cell, 2010 Jul shRNA TG310588
Pcdh17 PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death Signal Transduction and Targeted Therapy, 2019 Nov shRNA TL705847
PCDH7 PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function Sci Rep, 2020 Jul shRNA TR700521
PCLO Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms Sci Rep, 2018 Nov shRNA TF502633
pCMVENTRY Kinesin KIF4A transports integrin ß1 in developing axons of cortical neurons Mol. Cell. Neurosci., 2014 Sep shRNA TR30013
PCMVMIR Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells Nature July 2014, 2014 Jul shRNA TR30021
PCSK5 Furin Is the Major Proprotein Convertase Required for KISS1-to-Kisspeptin Processing PLoS ONE, Jan 2014., 2014 Jan shRNA TF310565
PCSK7 Furin Is the Major Proprotein Convertase Required for KISS1-to-Kisspeptin Processing PLoS ONE, Jan 2014., 2014 Jan shRNA TF310564
PCSK9 ß-Estradiol Results in a PCSK9-Dependent Increase in LDLR Levels in Human Hepatic HuH7 Cells FEBS J., 2015 Apr shRNA TG302581
PCTM1 The MicroRNA 15a/16–1 Cluster Down-regulates Protein Repair Isoaspartyl Methyltransferase in Hepatoma Cells: IMPLICATIONS FOR APOPTOSIS REGULATION J. Biol. Chem., Dec 2011; 286: 43690 - 43700., 2011 Dec shRNA
PDCD4 Expression of TRPM8 in human reactive lymphoid tissues and mature B-cell neoplasms Oncol Lett, 2018 Nov shRNA TG302573
PDCD4 Euxanthone Impairs the Metastatic Potential of Osteosarcoma by Reducing COX-2 Expression Anat Rec (Hoboken) 2018, 2018 Oct shRNA TG302573
PDCD4 MicroRNA-429 sensitizes pancreatic cancer cells to gemcitabine through regulation of PDCD4 Am J Transl Res, 2017 Nov shRNA TG302573
PDCD6 ALG2 Influences T cell apoptosis by regulating FASLG intracellular transportation Biochem. J., 2020 Aug shRNA TG310558
PDCD6 Apoptosis-linked gene 2 promotes breast cancer growth and metastasis by regulating the cytoskeleton Oncotarget, 2017 Jan shRNA TG310558