siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PRKCI Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors Cell Adh Migr, 2018 May siRNA SR321426
PRKCI FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR321426
PRKCZ Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion Cell adhesion & migration, 2021 Dec siRNA SR321432
PRKCZ The modulation of actin dynamics via atypical Protein Kinase-C activated Cofilin regulates metastasis of colorectal cancer cells Cell Adh Migr, 2019 Dec siRNA SR321432
PRKCZ Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes Oncol Lett, 2019 Feb siRNA SR321432
PRKCZ Analysis of PKC‑ζ protein levels in normal and malignant breast tissue subtypes Oncol Lett, 2018 Dec siRNA SR321432
PRKCZ Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors Cell Adh Migr, 2018 May siRNA SR321432
PRKD1 A role for PKD1 in insulin secretion downstream of P2Y1 receptor activation in mouse and human islets Physiol Rep, 2019 Oct siRNA SR421194
Prkd1 The tumor promoter-activated protein kinase Cs are a system for regulating filopodia Cytoskeleton (Hoboken) 2017, 2017 May siRNA SR421194
PRKDC Identification of PRKDC (protein kinase, DNA-activated, catalytic polypeptide) as an essential gene for colorectal cancer (CRCs) cells Gene, 2016 Mar siRNA SR303748
PRKN Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson\'s disease models Aging, 2021 Apr siRNA SR303355
PRKN Type 2 diabetes-induced hyposalivation of the submandibular gland through PINK1/Parkin-mediated mitophagy J. Cell. Physiol., 2019 Jun siRNA SR303355
PRKN Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD(+)/SIRT1 Reduction Cell, 2014 May siRNA SR303355
PRKN Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy Cell Biosci 16 4 1. April 2014, 2014 Apr siRNA SR303355
PRNP The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through Dipeptidyl Aminopeptidase-like protein 6 J. Biol. Chem., 2013 Nov siRNA SR303776
PROM1 Astrocytes influence medulloblastoma phenotypes and CD133 surface expression PLoS ONE, 2020 Jul siRNA SR305838
PROM1 Silencing of CD133 inhibits GLUT1-mediated glucose transport through downregulation of the HER3/Akt/mTOR pathway in colon cancer FEBS Lett., 2019 Nov siRNA SR305838
PROM1 Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer Pancreatology, 2016 Sep siRNA SR305838
PS100001 Macrophage-Derived Delta-like 1 Enhances Interleukin-6 and Matrix Metalloproteinase-3 Production by Fibroblast-Like Synoviocytes in Arthritic Mice Arthritis & rheumatology, 2014 Jun siRNA SR30004
PS100020 SDF1a-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells Eur. J. Immunol., 2014 Oct siRNA SR30004
Psmb5 Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models Autophagy, 2022 Jan siRNA SR512544
Psmd13 Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital Amaurosis J. Neurosci., 2016 May siRNA SR412711
PSMD13 Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins Advances in experimental medicine and biology, 2015 Oct siRNA SR303852
PSMD13 Temperature-sensitive retinoid isomerase activity of RPE65 mutants associated with Leber Congenital Amaurosis J. Biochem., 2015 Mar siRNA SR303852
PSMD13 Rescue of enzymatic function for disease-associated RPE65s containing various missense mutations in non-active sites J. Biol. Chem., 2014 May siRNA SR303852
PSMD2 Angiopoietin-2 secretion by endothelial cells exosome: regulation by the PI3K/Akt/eNOS and syndecan 4/syntenin pathways J. Biol. Chem., 2013 Nov siRNA SR303842
PSMD3 The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium J. Cell Biol., 2015 Jul siRNA SR416821
PSME3 PSME3 Promotes TGFB1 Secretion by Pancreatic Cancer Cells to Induce Pancreatic Stellate Cell Proliferation J. Cancer, 2019 May siRNA SR323025
PSMF1 Molecular and Cellular Roles of PI31 (PSMF1) in Regulation of Proteasome Function J. Biol. Chem. April 2014, 2014 Apr siRNA SR306299
PTEN miR-3691-5p promotes hepatocellular carcinoma cell migration and invasion through activating PI3K/Akt signaling by targeting PTEN Onco Targets Ther, 2019 Jun siRNA SR321496
PTEN Jarid2 enhances the progression of bladder cancer through regulating PTEN/AKT signaling Life Sci., 2019 May siRNA SR321496
PTEN T cells transduce T cell receptor signal strength by generating different phosphatidylinositols J. Biol. Chem., 2019 Jan siRNA SR426694
PTEN SIX1 reduces the expression of PTEN via activating PI3K/AKT signal to promote cell proliferation and tumorigenesis in osteosarcoma Biomed. Pharmacother., 2018 May siRNA SR321496
PTEN Neuronal RARß Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration J. Neurosci., 2015 Nov siRNA SR413443
PTEN PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: Modulation by PTEN J. Clin. Endocrinol. Metab., 2014 May siRNA SR303860
PTEN NVP-BEZ235, a dual PI3K/mTOR inhibitor, induces cell death through alternate routes in prostate cancer cells depending on the PTEN genotype Apoptosis, 2014 Mar siRNA SR303860
PTGES miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH Biochem. Biophys. Res. Commun.2017, 2017 Oct siRNA SR306338
PTGS2 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway J. Exp. Clin. Cancer Res., 2020 Jun siRNA SR303873
PTGS2 Differential expression of cyclooxygenase-2 in metastatic melanoma affects progression free survival Oncotarget, 2016 Aug siRNA SR303873
PTGS2 Phenolcarboxylic acids from medicinal herbs exert anticancer effects through disruption of COX-2 activity Phytomedicine, 2014 Jun siRNA SR303873
PTGS2 MiR-21 Targets 15-PGDH and Promotes Cholangiocarcinoma Growth Mol. Cancer Res. April 2014, 2014 Apr siRNA SR303873
PTGS2 Ubiquitin-Proteasomal Degradation of COX-2 in TGF-ß Stimulated Human Endometrial Cells Is Mediated Through Endoplasmic Reticulum Mannosidase I Endocrinology, Jan 2012; 153: 426 - 437., 2012 Jan siRNA SR303873
PTK2 A Non-genetic Mechanism for Chemoresistance in Lung Cancer: The Role of Integrin β4/Paxillin Axis bioRxiv, 2019 Sep siRNA SR303877
PTK2 T cells transduce T cell receptor signal strength by generating different phosphatidylinositols J. Biol. Chem., 2019 Jan siRNA SR421142
PTK2 Phosphoinositide 3-kinase p85beta regulates invadopodium formation Biol Open, 2014 Sep siRNA SR421142
PTPN14 miR-4516 predicts poor prognosis and functions as a novel oncogene via targeting PTPN14 in human glioblastoma Oncogene, 2018 Dec siRNA SR303895
PTX3 K284-6111 Alleviates Memory Impairment and Neuroinflammation in Tg2576 Mice by Inhibition of Chitinase-3-like 1 Regulating ERK Dependent PTX3 Pathway Research Square, 2020 Jun siRNA SR412848
PTX3 Constitutive Expression of PTX3 by Human Amniotic Membrane Cells Leads to Formation of the HC-HA/PTX3 Complex J. Biol. Chem., 2014 Mar siRNA SR303915
PTX3 PTX3 Controls Activation of Matrix Metalloproteinase 1 and Apoptosis in Conjunctivochalasis Fibroblasts Invest. Ophthalmol. Vis. Sci., Jun 2012; 53: 3414 - 3423., 2012 Jun siRNA SR303915
PUM1 PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells Blood, 2017 Feb siRNA SR306467