shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PDCD6 Structural and Functional Study of Apoptosis-linked Gene-2/Heme-binding Protein 2 Interactions in HIV-1 Production J. Biol. Chem., 2016 Oct shRNA TR310558
PDGFRA PDGFRa Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer EBioMedicine, 2016 Sep shRNA TR310535
PDGFRA Culture dimensionality influences the resistance of glioblastoma stem-like cells to multikinase inhibitors Mol. Cancer Ther. April 2014, 2014 Apr shRNA TR310535
PDGFRB Primary breast cancer cell culture yields intra-tumor heterogeneous subpopulations expressing exclusive patterns of receptor tyrosine kinases BMC Cancer, 2016 Sep shRNA TG310534
PDIA2 Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum The EMBO Journal 29, 4185-4197 (5 November 2010) doi:10.1038/emboj.2010.273 Article, 2010 Nov shRNA TR310528
PDK1 Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions Cell Rep, 2018 Feb shRNA TR517458
PDK1 HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism J. Immunol., May 2009; 182: 5800 - 5809., 2009 May shRNA TR320448
PDK1 Targeting Endoplasmic Reticulum Stress and Akt with OSU-03012 and Gefitinib or Erlotinib to Overcome Resistance to Epidermal Growth Factor Receptor Inhibitors Cancer Res., Apr 2008; 68: 2820 - 2830, 2008 Apr shRNA TR320448
PDK2 Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells Hepatology, 2014 Oct shRNA TR320449
PDK4 Identification of ERR alpha as a specific partner of PGC-1 alpha for the activation of PDK4 gene expression in muscle FEBS J., Apr 2006; 273: 1669-1680., 2006 Apr shRNA TR320451
Per1 Period1 gates the circadian modulation of memory-relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK. Journal of neurochemistry, 2017 Jun shRNA TL501619
Per1 Period1 gates the circadian modulation of memory-relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK J. Neurochem., 2016 Jun shRNA TG501619
PERP PERP, a p53 pro-apoptotic target, mediates apoptotic cell death in renal ischemia Am J Physiol Renal Physiol, Jan 2009; 10.1152/ajprenal.90438.2008., 2009 Apr shRNA TR302542
PEX5 A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS Nature Cell Biology doi:10.1038/ncb2822, 2013 Aug shRNA TG310491
Pfkfb3 Differential role of neuronal glucose and PFKFB3 in memory formation during development. Glia, 2022 Sep shRNA TL712366
PFKFB3 A ROLE FOR PFKFB3/IPFK2 IN OVERNUTRITION-ASSOCIATED ADIPOSE TISSUE AND INTESTINE INFLAMMATORY RESPONSES AND INSULIN RESISTANCE Thesis, 2013 Nov shRNA TR517196
PFKFB3 Disruption of Inducible 6-Phosphofructo-2-kinase Ameliorates Diet-induced Adiposity but Exacerbates Systemic Insulin Resistance and Adipose Tissue Inflammatory Response J. Biol. Chem., Feb 2010; 285: 3713 - 3721, 2010 Feb shRNA TR517196
PGAM2 Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase Cancer Res., 2014 May shRNA TG310477
Pgam5 A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy Redox Biology, 2021 Nov shRNA TR702898
Pgap2 Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival eLife, 2019 Jun shRNA TL507043
pGFP-C-shLenti Whole-transcriptome microarray analysis reveals regulation of Rab4 by RBM5 in neurons Neuroscience, 2017 Aug shRNA TR30021
PHF1 Polycomb Group Protein PHF1 Regulates p53-dependent Cell Growth Arrest and Apoptosis J. Biol. Chem., Jan 2013; 288: 529 - 539., 2013 Jan shRNA TG302514
PHLPP1 Oncogenic suppression of PHLPP1 in human melanoma. Oncogene, 2014 Dec shRNA TL302501
PI3K Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival Mol. Cell. Biol., Mar 2011; 10.1128/MCB.01313-10, 2011 Mar shRNA
PIEZO1 Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis Channels, 2022 Aug shRNA TF313084
PIEZO2 A critical role for Piezo2 channels in the mechanotransduction of mouse proprioceptive neurons Sci Rep, 2016 May shRNA TR509519
PIK3C2A Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan Nature Communications, 2022 Jan shRNA TL310432
Pik3c3 Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells Cancers, 2019 Oct shRNA TF506698
Pik3c3 Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells Elife, 2016 Jun shRNA TG506698
PIK3C3 pp60c-Src Phosphorylates and Activates Vacuolar Protein Sorting 34 to Mediate Cellular Transformation Cancer Res., Jul 2010; 70: 5974 - 5983, 2010 Jul shRNA TR310429
Pik3ca Phosphoinositide 3-kinase beta controls replication factor C assembly and function Nucleic Acids Res., Jan 2013; 41: 855 - 868., 2013 Jan shRNA TG501641
PIK3CB Nuclear phosphoinositide 3-kinase ß controls double-strand break DNA repair PNAS, Apr 2010; 107: 7491 - 7496, 2010 Apr shRNA TR310427
Pik3cb Specific function of phosphoinositide 3-kinase beta in the control of DNA replication Proceedings of the National Academy of Sciences of the United States of America, 2009 May shRNA TF711892
PIK3CB Specific function of phosphoinositide 3-kinase beta in the control of DNA replication PNAS, May 2009; 106: 7525 - 7530., 2009 May shRNA TR310427
Pik3r1 Phosphoinositide 3-kinase beta controls replication factor C assembly and function Nucleic Acids Res., Nov 2012; 10.1093/nar/gks1095., 2012 Nov shRNA TG509680
PIK3R1 p85ß phosphoinositide 3-kinase subunit regulates tumor progression PNAS, Jun 2012; 10.1073/pnas.1118138109., 2012 Jun shRNA TR307821
PIM1 miR24-2 accelerates progression of liver cancer cells by activating Pim1 through tri-methylation of Histone H3 on the ninth lysine J. Cell. Mol. Med., 2020 Feb shRNA TF315503
PIM1 HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372 Oncotarget, 2017 Jul shRNA TG315503
PINK1 Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys Autophagy, 2019 May shRNA TR705269
PINK1 Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy J. Neurochem., 2015 Oct shRNA TR320728
PINK1 Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission J. Biol. Chem., May 2009; 284: 13843 - 13855., 2009 May shRNA TR320728
Pip5k1b DNA damage causes rapid accumulation of phosphoinositides for ATR signaling Nat Commun, 2017 Dec shRNA TF517012
Pip5k1b Acute and Temporal Expression of Tumor Necrosis Factor (TNF)-α-stimulated Gene 6 Product, TSG6, in Mesenchymal Stem Cells Creates Microenvironments Required for Their Successful Transplantation into Muscle Tissue The Journal of Biological Chemistry, 2015 Sep shRNA TF517012
PITX1 Downregulated PITX1 Modulated by MiR-19a-3p Promotes Cell Malignancy and Predicts a Poor Prognosis of Gastric Cancer by Affecting Transcriptionally Activated PDCD5 Cell. Physiol. Biochem., 2018 May shRNA TG310405
PIWIL2 Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis Oncotarget, 2016 Oct shRNA TG302470
PKM Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein Viruses, 2021 Mar shRNA TG302462
Pkm Functional polarization of tumour-associated macrophages by tumour-derived lactic acid Nature July 2014, 2014 Jul shRNA TG511241
Pla2g6 H2O2-activated mitochondrial phospholipase iPLA2? prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GPR40, and regulates insulin secretion in pancreatic ß-cells Antioxid. Redox Signal., 2015 Apr shRNA TG700671
Pla2g6 Group VIA phospholipase A2 in both host and tumor cells is involved in ovarian cancer development FASEB J, Jun 2010; 10.1096/fj.10-161356, 2010 Jun shRNA TR515018
plasmid Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4 PNAS, Sep 2011; 108: 16098 - 16103., 2011 Oct shRNA