siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PUM2 PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells Blood, 2017 Feb siRNA SR308223
PURB MaTAR25 LncRNA Regulates the Tensin1 Gene to Impact Breast Cancer Progression bioRxiv, 2020 Feb siRNA SR410793
PXN Paxillin is positively correlated with the clinicopathological factors of colorectal cancer, and knockdown of Paxillin improves sensitivity to cetuximab in colorectal cancer cells ONCOLOGY REPORTS, 2016 Jan siRNA SR303929
PYM1 CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation Genes Dev., 2015 Nov siRNA SR313474
RAB27B Hypomethylated Rab27b is a progression-associated prognostic biomarker of glioma regulating MMP-9 to promote invasion Oncol. Rep., 2015 Jul siRNA SR303953
RAB31 LRG‐1 promotes fat graft survival through the RAB31‐mediated inhibition of hypoxia‐induced apoptosis Journal of Cellular and Molecular Medicine, 2022 Mar siRNA SR307545
RAB3A Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP J. Neurosci., 2016 Aug siRNA SR402766
RAC1 Knockdown of RhoGDI2 represses human gastric cancer cell proliferation, invasion and drug resistance via the Rac1/Pak1/LIMK1 pathway Cancer Lett., 2020 Aug siRNA SR321562
RAC1 Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy Cells, 2020 Mar siRNA SR321562
RAC1 MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes Nat Commun, 2017 Jan siRNA SR303958
RACK1 Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells Sci Rep, 2018 May siRNA SR307048
RAD18 Impacts of Arsenic on Rad18 and Translesion Synthesis Toxicology and applied pharmacology, 2023 Apr siRNA SR311213
RAD51 New RAD51 Inhibitors to Target Homologous Recombination in Human Cells Genes, 2021 Jun siRNA SR321568
RAD51B Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis bioRxiv, 2018 Mar siRNA SR303968
RAD51C Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis bioRxiv, 2018 Mar siRNA SR303967
RAD51D Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis bioRxiv, 2018 Mar siRNA SR303970
RAF1 The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux Autophagy, 2015 Jun siRNA SR303972
RALA Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C Oncotarget, 2016 Dec siRNA SR303975
RAMAC RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs Nucleic Acids Research, 2017 Oct siRNA SR313193
RARA Regulation of myelination by exosome associated retinoic acid release from NG2-positive cells J. Neurosci., 2019 Feb siRNA SR414999
RARB RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells FASEB J., 2018 Sep siRNA SR414645
RARRES1 Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway Kidney international, 2021 Jun siRNA SR303993
RB1CC1 ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis Journal of experimental & clinical cancer research : CR, 2021 Apr siRNA SR306576
RBFOX2 Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors Cellular and Molecular Life Sciences, 2022 Aug siRNA SR308351
Rbpj A genetic cell context-dependent role for ZEB1 in lung cancer Nat Commun, 2016 Jul siRNA SR415718
RBPMS Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors Cellular and Molecular Life Sciences, 2022 Aug siRNA SR307544
Re-suspension Buffer Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia Sci Rep, 2020 Feb siRNA SR30005
Re-suspension Buffer Knockdown RIP-1 inhibits production of oxLDL-induced inflammatory cytokines and promotes ABCA1 expression in macrophages Int J Clin Exp Med, 2018 Jun siRNA SR30005
Re-suspension Buffer Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox Sci Rep, 2017 Sep siRNA SR30005
REG3B REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway Communications biology, 2021 Jun siRNA SR404149
REL RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model Prostate, 2020 Feb siRNA SR304027
REL NPD1-mediated stereoselective regulation of BIRC3 expression through cREL is decisive for neural cell survival Cell Death Differ., 2015 Jan siRNA SR304027
Rela ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation Cellular and Molecular Life Sciences, 2022 Feb siRNA SR427138
RELA Cytomegalovirus infection of glioblastoma cells leads to NF-κB dependent upregulation of the c-MET oncogenic tyrosine kinase Cancer letters, 2021 May siRNA SR321602
RELA c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR321602
RELA The Harsh Microenvironment in Early Breast Cancer Selects for a Warburg Phenotype bioRxiv, 2020 Apr siRNA SR321602
RELA RELA is Sufficient to Mediate Interleukin-1 (IL-1) Repression of Androgen Receptor Expression and Activity in LNCaP Disease Progression Model bioRxiv, 2019 Sep siRNA SR321602
RELA Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness Oncogenesis, 2018 Nov siRNA SR321602
RELA Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression Theranostics, 2017 Oct siRNA SR304030
RELA FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR321602
RELA ELF4 is critical for induction of type I interferon and the host antiviral response Nat. Immunol. 1237-46, 2013 Nov siRNA SR304030
RELB RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model Prostate, 2020 Feb siRNA SR304031
REST Perturbations of Neuron-Restrictive Silencing Factor Modulate Corticotropin-Releasing Hormone Gene Expression in the Human Cell Line BeWo Mol Neuropsychiatry, 2018 Sep siRNA SR321606
REST Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease J. Cell. Mol. Med., 2017 May siRNA SR427708
REST Epigenetic gene regulation by TET3 and 5-hydroxymethylcytosine during retinal maturation Thesis, 2015 Jun siRNA SR304036
REST TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression Cell Rep, 2015 Apr siRNA SR304036
Rgcc Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease Cell Transplant, 2017 Apr siRNA SR402545
RHEB Role of RHEB in Regulating Differentiation Fate of Mesenchymal Stem Cells for Cartilage and Bone Regeneration Int J Mol Sci, 2017 Apr siRNA SR304066
RHEB RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration J Tissue Eng Regen Med, 2016 Apr siRNA SR304066
RHOBTB1 The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer. International journal of oncology, 2014 Jan siRNA SR306632