siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
RICTOR mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer Oncogene, 2018 Aug siRNA SR316744
RICTOR Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression Theranostics, 2017 Oct siRNA SR316744
RIPK1 RIPK1 is a negative mediator in Aquaporin 1-driven triple-negative breast carcinoma progression and metastasis NPJ breast cancer, 2021 May siRNA SR418761
RIPK1 Knockdown RIP-1 inhibits production of oxLDL-induced inflammatory cytokines and promotes ABCA1 expression in macrophages Int J Clin Exp Med, 2018 Jun siRNA SR418761
RIPK2 Receptor Interacting Protein-2 acts as negative regulator for nontypeable Haemophilus influenzae-induced mucin MUC5AC expression ntegrative Molecular Medicine, 2017 Aug siRNA SR305775
RIPK3 RIP3 facilitates necroptosis through CaMKII and AIF after intracerebral hemorrhage in mice Neuroscience Letters, 2021 Feb siRNA SR323326
RIPK3 Phagocytosis of environmental or metabolic crystalline particles induces cytotoxicity by triggering necroptosis across a broad range of particle size and shape Sci Rep, 2017 Nov siRNA SR307548
RMDN3 Altered Protein Interactions of the Endogenous Interactome of PTPIP51 towards MAPK Signaling Biomolecules, 2017 Jul siRNA SR310551
RNASEL Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR304081
RNMT RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs Nucleic Acids Research, 2017 Oct siRNA SR305750
ROBO1 Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo Biomaterials, 2019 Apr siRNA SR321632
ROCK1 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway J. Exp. Clin. Cancer Res., 2020 Jun siRNA SR304092
ROCK1 Targeting the Metastasis Suppressor, NDRG1, Using Novel Iron Chelators: Regulation of Stress Fiber-Mediated Tumor Cell Migration via Modulation of the ROCK1/pMLC2 Signaling Pathway Mol. Pharmacol., Feb 2013; 83: 454 - 469., 2013 Feb siRNA SR422726
ROCK2 Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth Cancers (Basel) 2019, 2019 Dec siRNA SR306287
ROCK2 Rho-associated kinase is a therapeutic target in neuroblastoma Proc. Natl. Acad. Sci. U.S.A., 2017 Jul siRNA SR306287
RORA Molecular Mechanisms of Control of Differentiation of Regulatory T-Lymphocytes by Exogenous Melatonin Dokl. Biochem. Biophys., 2019 May siRNA SR304094
RPS19 Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA Proc. Natl. Acad. Sci. U.S.A., 2016 Nov siRNA SR304179
RPS6 Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS -mutant lung cancer Journal of Experimental & Clinical Cancer Research : CR, 2022 Jan siRNA SR304160
RPS6KA1 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity Science (New York, N.Y.), 2022 Apr siRNA SR304161
RPS6KB1 Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection Mol. Cell, 2018 Dec siRNA SR304164
RPS6KB1 Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection Mol. Cell, 2018 Dec siRNA SR416706
RPS6KB1 TAK1 inhibition by natural cyclopeptide RA-V promotes apoptosis and inhibits protective autophagy in Kras-dependent non-small-cell lung carcinoma cells RSC Adv., 2018 Jun siRNA SR304164
RPS6KB1 Nox4 is a Target for Tuberin Deficiency Syndrome Sci Rep, 2018 Feb siRNA SR304164
RPTOR mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer Oncogene, 2018 Aug siRNA SR324724
RPTOR Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression Theranostics, 2017 Oct siRNA SR311531
RSPO1 The role of R-spondin 1 through activating Wnt/β-catenin in the growth, survival and migration of ovarian cancer cells Gene, 2019 Mar siRNA SR317182
RSPO1 Sirtuin-6 Preserves R-spondin-1 Expression and Increases Resistance of Intestinal Epithelium to Injury in Mice Mol Med., 2017 Oct siRNA SR407587
RUNX2 Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma Int. J. Cancer, 2014 Oct siRNA SR300606
RUNX3 MicroRNA‑629 inhibition suppresses the viability and invasion of non‑small cell lung cancer cells by directly targeting RUNX3 Mol Med Rep, 2019 Feb siRNA SR108475
RXFP1 Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1 Theranostics, 2020 Jan siRNA SR419891
RYR2 Molecular characterization of the calcium release channel deficiency syndrome JCI Insight, 2020 Jul siRNA SR304208
S100A4 miR-187-3p inhibits the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting S100A4 Cancer Lett., 2016 Aug siRNA SR304214
S100A8 Peripheral immune tolerance by prolactin-induced protein originated from human invariant natural killer T cells Bioengineered, 2021 Dec siRNA SR304218
S100A8 Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance J. Leukoc. Biol., 2016 Nov siRNA SR304218
S100A8 Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition Cell, 2014 Oct siRNA SR304218
S100A9 Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition Cell, 2014 Oct siRNA SR304219
S1PR2 Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells Allergy July 2014, 2014 Jul siRNA SR306152
S1pr3 Smad3 Deficiency Leads to Mandibular Condyle Degradation via the Sphingosine 1-Phosphate (S1P)/S1P3 Signaling Axis Am. J. Pathol., 2015 Aug siRNA SR412767
SC319768 TLR2 signaling directs NO-dependent MMP-9 induction in mouse microglia Neurosci. Lett. April 2014, 2014 Apr siRNA SR304856
SCARB1 High-density lipoprotein and apolipoprotein A-I inhibit palmitate-induced translocation of toll-like receptor 4 into lipid rafts and inflammatory cytokines in 3T3-L1 adipocytes Biochem. Biophys. Res. Commun, 2017 Jan siRNA SR416342
SCD IDH1 mutations induce organelle defects via dysregulated phospholipids Nature communications, 2021 Jan siRNA SR304248
SCD Down-regulation of stearoyl-CoA desaturase-1 increases susceptibility to palmitic-acid-induced lipotoxicity in human trophoblast cells The Journal of nutritional biochemistry, 2017 Nov siRNA SR304248
SCD 17ß-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells BMC Cancer, 2015 May siRNA SR304248
SCD1 Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins Cell Rep. 2013 Sep 26;4(6):1072-81, 2013 Sep siRNA SR411990
SCLY Diet-induced obesity in the selenocysteine lyase knockout mouse Antioxid. Redox Signal., 2015 Jul siRNA SR414271
SCN3B Biphasic voltage-dependent inactivation of human NaV1.3, 1.6 and 1.7 Na+channels expressed in rodent insulin-secreting cells J. Physiol. (Lond.) 2018, 2018 Feb siRNA SR505961
SCO2 SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1–Trx Complex Mol. Cell. Biol., Apr 2013; 33: 1285 - 1302., 2013 Apr siRNA SR306726
Scrambled Control Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3 Oncology reports, 2021 Jul siRNA SR30004
Scrambled Control PARP1 Is Targeted by miR-519a-3p and Promotes the Migration, Invasion, and Tube Formation of Ovarian Cancer Cells Cancer biotherapy & radiopharmaceuticals, 2021 May siRNA SR30004
Scrambled Control N-cadherin mediates the migration of bone marrow-derived mesenchymal stem cells toward breast tumor cells Theranostics, 2021 May siRNA SR30004