shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PRDX1 Dithiol-based Compounds Maintain Expression of Antioxidant Protein Peroxiredoxin 1 That Counteracts Toxicity of Mutant Huntingtin J. Biol. Chem., Jun 2012; 287: 22717 - 22729., 2012 Jun shRNA TR302287
PRDX2 Silencing peroxiredoxin-2 sensitizes human colorectal cancer cells to ionizing radiation and oxaliplatin Cancer Lett, 2016 Dec shRNA TR310194
PRDX5 Peroxiredoxin 5 is involved in cancer cell invasion and tumor growth of oral squamous cell carcinoma. Oral diseases, 2021 May shRNA TL310192
PRDX5 Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc J. Biol. Chem., Mar 2009; 284: 6520 - 6529., 2009 Mar shRNA TR503057
PRDX6 Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration Free Radic. Biol. Med., 2016 Apr shRNA TR310191
pRFP-C-RS Triclosan Impairs Hippocampal Synaptic Plasticity and Spatial Memory in Male Rats Front Mol Neurosci, 2018 Nov shRNA TR30014
PRKAA1 DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide Eur. J. Pharmacol., 2019 Sep shRNA TG320461
PRKAA1 Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release from the endoplasmic reticulum by AMP-activated kinase modulators Cell Calcium, 2019 Jan shRNA TG320461
PRKAA1 Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity Sci Rep, 2017 May shRNA TR505729
PRKAA1 Underactivation of the adiponectin-adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression Clin Exp Metastasis. 2013 Oct 5, 2013 Oct shRNA TG505729
PRKAA2 AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation J. Cell. Sci., 2018 Jul shRNA TG320462
PRKAA2 Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells Breast Cancer Res., 2014 Aug shRNA TF320462
PRKAA2 AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation Am J Physiol Renal Physiol, Dec 2011; 301: F1177 - F1192., 2011 Dec shRNA TR320462
PRKAB1 Reduced expression of AMPK-ß1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer Mol. Cancer, 2014 Mar shRNA TG315591
Prkca Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology Nat Commun, 2018 Jan shRNA TG501653
PRKCA Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKC{ALPHA} phosphorylation , 2009 Jul shRNA TR320466
PRKCA PCPH/ENTPD5 Expression Confers to Prostate Cancer Cells Resistance against Cisplatin-Induced Apoptosis through Protein Kinase C–Mediated Bcl-2 Stabilization Cancer Res., Jan 2009; 69: 102 - 110., 2009 Jan shRNA TR320466
PRKCD Protein Kinase C Delta restrains growth in ACTH-secreting pituitary adenoma cells Mol. Cell. Endocrinol., 2015 Oct shRNA TG513052
PRKCD Distinct ICD substrate modifications selectively regulate ectodomain cleavage of NRG1 or CD44 Mol. Cell. Biol., 2015 Jul shRNA TG320468
PRKCD Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281 Cell. Signal., 2015 May shRNA TR320468
PRKCD PKCd maintains phenotypes of tumor initiating cells through cytokine-mediated autocrine loop with positive feedback Oncogene, 2015 Mar shRNA TG320468
PRKCD Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy J. Cell. Physiol., 2014 Dec shRNA TG513052
PRKCD miR-26a Plays an Important Role in Cell Cycle Regulation in ACTH-Secreting Pituitary Adenomas by Modulating Protein Kinase C Endocrinology, May 2013; 154: 1690 - 1700., 2013 May shRNA TG320468
PRKCD Sprouty2 Interacts with Protein Kinase C and Disrupts Phosphorylation of Protein Kinase D1 J. Biol. Chem., Jul 2009; 284: 19623 - 19636, 2009 Jul shRNA TR320468
PRKCD Connexin43 Potentiates Osteoblast Responsiveness to Fibroblast Growth Factor 2 via a Protein Kinase C-Delta/Runx2–dependent Mechanism Mol. Biol. Cell, Jun 2009; 20: 2697 - 2708, 2009 Jun shRNA TR320468
PRKCD PCPH/ENTPD5 Expression Enhances the Invasiveness of Human Prostate Cancer Cells by a Protein Kinase C{delta} Dependent Mechanism Cancer Res. 2007 Nov 15;67(22):10859-68, 2007 Nov shRNA TR320468
PRKCE Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281 Cell. Signal., 2015 May shRNA TR320469
PRKCI PRKCI negatively regulates autophagy via PIK3CA/AKT-MTOR signaling Biochem. Biophys. Res. Commun., 2016 Feb shRNA TR320472
PRKCI Identification of a Small Molecule with Synthetic Lethality for K-Ras and Protein Kinase C Iota Cancer Res. 2008; 68(18): p. 7403-7408, 2008 Sep shRNA TR320472
PRKCQ Suppression of protein kinase C theta contributes to enhanced myogenesis In vitro via IRS1 and ERK1/2 phosphorylation BMC Cell Biol. 2013 Sep 21;14:39., 2013 Sep shRNA TG501657
PRKCZ Identification of a Small Molecule with Synthetic Lethality for K-Ras and Protein Kinase C Iota Cancer Res. 2008; 68(18): p. 7403-7408, 2008 Sep shRNA TR320477
PRKDC DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes PLoS ONE, 2017 Jul shRNA TR320478
PRKN Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance Mol. Neurobiol., 2015 Nov shRNA TG310609
PRMT5 Protein Arginine Methyltransferase 5 (PRMT5) Signaling Suppresses Protein Kinase C- and p38-dependent Signaling and Keratinocyte Differentiation J. Biol. Chem., Mar 2012; 287: 7313 - 7323., 2012 Mar shRNA TR310167
PROM1 Ultrasound-targeted microbubble destruction-mediated downregulation of CD133 inhibits epithelial-mesenchymal transition, stemness and migratory ability of liver cancer stem cells Oncol. Rep., 2015 Sep shRNA TG310163
PRPF39 Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation Journal of Virology, 2018 Jan shRNA TL302262
pRS Exonuclease-1 interacts with the transcriptional co-repressor KAP1 Matters, 2016 Aug shRNA TR20003
PRS Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection J. Exp. Med., Aug 2011; 208: 1823 - 1834., 2011 Aug shRNA
pRS The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of the Human Cytomegalovirus are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-{kappa}B Sites in Proliferating Cells J. Virol., May 2010; 84: 4481 - 4493, 2010 May shRNA
pRS vector HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer Nature (13 December 2009) doi:10.1038/nature08697 Letter, 2009 Dec shRNA
pRS vector Heparanase Alters Arterial Structure, Mechanics, and Repair Following Endovascular Stenting in Mice Circ. Res., Dec 2008; 10.1161/CIRCRESAHA.108.180695., 2008 Dec shRNA
pRS vector Tumor Suppressor Activity of CCAAT/Enhancer Binding Protein {alpha} Is Epigenetically Down-regulated in Head and Neck Squamous Cell Carcinoma Cancer Res. 2007 May 15;67(10):4657-64., 2007 May shRNA
PS100001 Funktionelle Charakterisierung des putativen Tumorsuppressors Epithelial Membrane Protein 3 Thesis, 2014 Jan shRNA TR30007
PS100001 CD109 plays a role in osteoclastogenesis PLoS ONE Apr2013, 2013 Apr shRNA TR30013
PS100027 Direct Transcriptional Repression of Zfp423 by Zfp521 Mediates a Bone Morphogenic Protein-Dependent Osteoblast versus Adipocyte Lineage Commitment Switch Mol. Cell. Biol., 2014 Aug shRNA TR30013
PSIP1 High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells Cell. Physiol. Biochem., 2018 Oct shRNA TR505629
PSME3 The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells Nat Commun, 2020 Aug shRNA TG302223
PSME3 REGγ potentiates TGF-β/Smad signal dependent epithelial-mesenchymal transition in thyroid cancer cells Cell. Signal., 2019 Sep shRNA TG302223
PSME3 REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway Cell Death Differ., 2019 Jun shRNA TG302223
PSME3 REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma Cell Death Dis, 2018 May shRNA TG302223