shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
PSME3 REGγ controls Hippo signaling and reciprocal NF-κB-YAP regulation to promote colon cancer Clin. Cancer Res., 2018 Feb shRNA TR501768
PSME3 REG? is critical for skin carcinogenesis by modulating the Wnt/ß-catenin pathway Nat Commun, 2015 Apr shRNA TG302223
PSME3 PA28 is a novel corepressor of HTLV-1 replication and controls viral latency Blood, Jan 2013; 121: 791 - 800., 2013 Jan shRNA TG302223
PSTPIP1 PSTPIP1 inhibition of TCR signalling depends on its SH3 domain FEBS J. July 2014, 2014 Jul shRNA TF310088
PTAFR Feed forward reciprocal activation of PAFR and STAT3 regulates epithelial-mesenchymal transition in non-small cell lung cancer Cancer Res., 2015 Sep shRNA TR310087
PTAFR Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinoma Oncogene, 2015 Feb shRNA TR310087
PTBP1 Integrated analysis of a compendium of RNA-Seq datasets for splicing factors bioRxiv, 2020 Mar shRNA TG501773
PTEN PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma Scientific Reports, 2021 Apr shRNA TL320498
PTEN F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway Biomed. Pharmacother., 2018 Nov shRNA TG320498
PTEN Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a Mol. Cancer, 2018 Jun shRNA TG320498
PTEN Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN Cell Death Dis, 2018 Feb shRNA TG320498
PTEN Sensitivity of PTEN deficient non-small cell lung cancer to ionising radiation through inhibition of ataxia terangiectasia related 3 kinase (ATR) Cancer Research, 2017 Jul shRNA TG320498
PTEN Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways PLoS ONE, 2015 Aug shRNA TG320498
PTEN Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent Am J Clin Exp Urol, 2015 Aug shRNA TR320498
PTEN RIP1 Kinase Is an Oncogenic Driver in Melanoma Cancer Res., 2015 Feb shRNA TG320498
PTEN Atorvastatin overcomes gefitinib resistance in KRAS mutant human non-small cell lung carcinoma cells Cell Death Dis. 2013 Sep 26;4:e814. doi: 10.1038/cddis.2013.312., 2013 Sep shRNA TR320498
PTEN Short hairpin RNA against PTEN enhances regenerative growth of corticospinal tract axons after spinal cord injury J Neurosci. 2013 Sep 25;33(39):15350-61, 2013 Sep shRNA TR320498
PTEN Cooperation of protease-activated receptor 1 and integrin a?ß5 in thrombin-mediated lung cancer cell invasion Oncol. Rep., 2012 Aug shRNA TG320498
PTEN MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand J. Biol. Chem., Jun 2010; 285: 20281 - 20290, 2010 Jun shRNA TR320498
PTEN Immunosuppressive Cyclosporin A Activates AKT in Keratinocytes through PTEN Suppression: IMPLICATIONS IN SKIN CARCINOGENESIS J. Biol. Chem., Apr 2010; 285: 11369 - 11377, 2010 Apr shRNA TR320498
PTGER2 Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF?B pathways as well as Cox-2-mediated PGE2 /EP receptor signaling to enhance clathrin-mediated virus endocytosis Cell. Microbiol., 2015 Jan shRNA TG310080
PTGER4 Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF?B pathways as well as Cox-2-mediated PGE2 /EP receptor signaling to enhance clathrin-mediated virus endocytosis Cell. Microbiol., 2015 Jan shRNA TG310079
PTGER4 Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties Breast Cancer Res. Treat., 2013 Nov shRNA TR310079
PTGES Allergin-1 Immunoreceptor Suppresses House Dust Mite-Induced Allergic Airway Inflammation J. Immunol., 2020 Feb shRNA TG503457
PTGES Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1 Nat Commun, 2020 Jan shRNA TG318942
PTGR1 Leukotriene B4 BLT Receptor Signaling Regulates the Level and Stability of Cyclooxygenase-2 (COX-2) mRNA through Restricted Activation of Ras/Raf/ERK/p42 AUF1 Pathway J. Biol. Chem., Jul 2010; 285: 23568 - 23580., 2010 Jul shRNA TR311650
PTGS2 Analysis of the in vitro and in vivo effects of Photodynamic Therapy on Prostate Cancer by using new photosensitizers, protoporphyrin IX-polyamine derivatives Biochim. Biophys. Acta, 2017 Feb shRNA TR310074
PTGS2 Identification and validation of COX-2 as a co-target for overcoming cetuximab resistance in colorectal cancer cells Oncotarget, 2016 Oct shRNA TG310074
PTGS2 IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs Oncotarget, 2016 Feb shRNA TG310074
PTGS2 Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections Nat. Med., 2015 Aug shRNA TG310074
PTGS2 Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF?B pathways as well as Cox-2-mediated PGE2 /EP receptor signaling to enhance clathrin-mediated virus endocytosis Cell. Microbiol., 2015 Jan shRNA TG501784
PTGS2 Premetastatic soil and prevention of breast cancer brain metastasis Neuro Oncology, Jul 2013; 15: 891 - 903., 2013 Jul shRNA TG310074
PTK2 Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis Cell Rep, 2014 Nov shRNA TG514293
Ptk2b α 1 -Adrenergic receptor–PKC–Pyk2–Src signaling boosts L-type Ca 2+ channel Ca V 1.2 activity and long-term potentiation in rodents eLife, 2023 Jun shRNA TL710108
PTK2B The Human Ion Channel TRPM2 Modulates Neuroblastoma Cell Survival and Mitochondrial Function through Pyk2, CREB, and MCU Activation Am. J. Physiol., Cell Physiol., 2018 Jul shRNA TG320352
Ptk2b Sustained Gq-Protein Signaling Disrupts Striatal Circuits via JNK J. Neurosci., 2016 Oct shRNA TR501788
PTK7 Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis J. Biol. Chem. July 2014, 2014 Jul shRNA TF200451
PTP4A3 PRL-3 activates mTORC1 in Cancer Progression Sci Rep, 2015 Nov shRNA TR320652
Ptpn12 Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12 Mol. Cell. Biol., Jun 2013; 33: 2458 - 2469., 2013 Jun shRNA TG310066
Ptpn13 The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis. Oncogene, 2013 Nov shRNA TL510136
PTPN21 BMX negatively regulates BAK function thereby increasing apoptotic resistance to chemotherapeutic drugs Cancer Res., 2015 Feb shRNA TR310062
PTPN5 Tyrosine dephosphorylation is required for Bak activation in apoptosis The EMBO Journal (19 October 2010) doi:10.1038/emboj.2010.244 Article, 2010 Oct shRNA TR310058
PTPN6 SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma Neoplasia July 2014, 2014 Jul shRNA TG310057
PTPRH Tyrosine dephosphorylation is required for Bak activation in apoptosis The EMBO Journal, 2010 Nov shRNA TR310053
PTPRJ Tumor Suppressor Density-enhanced Phosphatase-1 (DEP-1) Inhibits the RAS Pathway by Direct Dephosphorylation of ERK1/2 Kinases J. Biol. Chem., Aug 2009; 284: 22048 - 22058, 2009 Aug shRNA TR310052
PTRH2 Downregulation of Bit1 expression promotes growth, anoikis resistance, and transformation of immortalized human bronchial epithelial cells via Erk activation-dependent suppression of E-cadherin Biochem. Biophys. Res. Commun.2017, 2017 Nov shRNA TR302190
PTRH2 The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells PLoS ONE, 2016 Sep shRNA TR302190
PTTG1 Pituitary tumor-transforming gene 1 regulates invasion of prostate cancer cells through MMP13 Tumour Biol., 2015 Jul shRNA TG310042
PTTG1 PTTG1 Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell Population J. Biol. Chem., Jun 2012; 287: 19516 - 19527., 2012 Jun shRNA TR310042
PUM2 Translational Regulation of Acetylcholinesterase by the RNA-binding Protein Pumilio-2 at the Neuromuscular Synapse J. Biol. Chem., Oct 2011; 286: 36492 - 36499., 2011 Jan shRNA TR302189