siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
SHH Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer Ther Adv Med Oncol, 2020 Mar siRNA SR304363
SI Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors Cell Adhesion & Migration, 2018 May siRNA SR321762
SI Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis International Journal of Oncology, 2017 Nov siRNA SR321762
Siah1 Disruption of the nuclear p53-GAPDH complex protects against ischemia-induced neuronal damage Mol Brain, 2014 Mar siRNA SR304369
SIAH2 Testin and filamin-C downregulation by acetylated Siah2 increases invasiveness of Helicobacter pylori-infected gastric cancer cells Int. J. Biochem. Cell Biol., 2018 Jul siRNA SR304370
Sigmar1 The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021 Apr siRNA SR426072
SIK1 SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype J. Leukoc. Biol., 2015 Nov siRNA SR315713
SIK2 SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype J. Leukoc. Biol., 2015 Nov siRNA SR308116
SIK3 The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling Sci Transl Med, 2018 Sep siRNA SR323570
SIK3 SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotype J. Leukoc. Biol., 2015 Nov siRNA SR308237
siRNA MicroRNA-708 Induces Apoptosis and Suppresses Tumorigenicity in Renal Cancer Cells Cancer Res., Oct 2011; 71: 6208 - 6219., 2011 Oct siRNA
siRNA Long-chain acyl-CoA synthetase 4 modulates prostaglandin E2 release from human arterial smooth muscle cells J. Lipid Res., Apr 2011; 52: 782 - 793, 2011 Apr siRNA
siRNA Scrambled Control Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-NMDA receptor coupling J Biol Chem. 2013 Oct 17, 2013 Oct siRNA SR30004
SIRT1 Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment Aging, 2020 Dec siRNA SR427400
SIRT1 Down-regulating miR-217-5p Protects Cardiomyocytes against Ischemia/Reperfusion Injury by Restoring Mitochondrial Function via Targeting SIRT1 Inflammation, 2020 Oct siRNA SR323581
SIRT1 Fruit of Hovenia dulcis Thunb. induces non-shivering thermogenesis through mitochondrial biogenesis and activation by SIRT1 in high fat diet-fed obese mice and primary cultured brown adipocytes J. Agric. Food Chem., 2020 May siRNA SR427400
SIRT1 Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD(+)/Sirt1 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats Stroke, 2017 Jun siRNA SR419269
SIRT1 TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue Int J Obes (Lond) 2017, 2017 Feb siRNA SR308256
Sirt1 Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice Neurobiology of Aging, 2016 Mar siRNA SR419269
SIRT1 Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target Lab. Invest., 2015 Sep siRNA SR308256
SIRT1 Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD(+)/SIRT1 Reduction Cell, 2014 May siRNA SR308256
SIRT2 A Succinate Ether Derivative of Tocotrienol Enhances Dickkopf-1 Gene Expression through Epigenetic Alterations in Malignant Mesothelioma Cells. Pharmacology, 2018 Nov siRNA SR323460
SIRT4 MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4 Aging (Albany NY), 2016 Feb siRNA SR308254
SIRT6 Sirtuin-6 Preserves R-spondin-1 Expression and Increases Resistance of Intestinal Epithelium to Injury in Mice Mol Med., 2017 Oct siRNA SR411215
SIRT6 The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells J. Cell. Biochem., 2015 Mar siRNA SR309840
SIVA1 Plumbagin inhibits proliferation and induces apoptosis of hepatocellular carcinoma by downregulating the expression of SIVA Drug Des Devel Ther, 2019 Apr siRNA SR307193
SKP2 Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma Sci Rep, 2018 Sep siRNA SR304388
SLC12A2 Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo Biomaterials, 2019 Apr siRNA SR304439
SLC12A7 Insulin-Like Growth Factor and SLC12A7 Dysregulation: A Novel Signaling Hallmark of Non-Functional Adrenocortical Carcinomas J. Am. Coll. Surg., 2019 Apr siRNA SR307307
SLC12A7 SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior Cell Commun. Signal, 2018 Jun siRNA SR307307
SLC1A5 Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer Front Oncol, 2019 Aug siRNA SR321780
SLC25A25 Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action Proc. Natl. Acad. Sci. U.S.A., 2020 Aug siRNA SR412336
Slc2a1 Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism Frontiers in Physiology, 2022 Nov siRNA SR503164
Slc2a3 Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism Frontiers in Physiology, 2022 Nov siRNA SR502308
Slc2a4 Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism Frontiers in Physiology, 2022 Nov siRNA SR515187
SLC30A8 Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress J. Biol. Chem., 2019 Oct siRNA SR325944
SLC31A1 Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells Sci Rep, 2017 Aug siRNA SR300931
SLC31A1 Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth Oncotarget, 2016 Jun siRNA SR300931
SLC35B4 SLC35B4, an Inhibitor of Gluconeogenesis, Responds to Glucose Stimulation and Downregulates Hsp60 among Other Proteins in HepG2 Liver Cell Lines Molecules, 2018 Jun siRNA SR313733
SLC39A14 Localization of ZIP14 and ZIP8 in HIBCPP Cells Brain Sciences, 2020 Aug siRNA SR308328
SLC39A14 Astrocytic expression of ZIP14 (SLC39A14) is part of the inflammatory reaction in chronic neurodegeneration with iron overload Glia, 2020 Feb siRNA SR506875
SLC39A14 Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14 Nutrients, 2019 Jun siRNA SR308328
SLC39A8 Localization of ZIP14 and ZIP8 in HIBCPP Cells Brain Sci, 2020 Aug siRNA SR311962
SLC39A8 Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14 Nutrients, 2019 Jun siRNA SR311962
SLC43A3 Transport Characteristics of 6-Mercaptopurine in Brain Microvascular Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Journal of pharmaceutical sciences, 2021 Jun siRNA SR309168
SLC4A11 Energy Crisis in Human and Mouse Models of SLC4A11-associated Corneal Endothelial Dystrophies bioRxiv, 2019 Dec siRNA SR313298
SLC7A11 Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury Cell Mol Gastroenterol Hepatol, 2019 May siRNA SR416143
SLC7A2 Degradation of AMPK-α1 sensitizes BRAF inhibitor-resistant melanoma cells to arginine deprivation Mol Oncol, 2017 Dec siRNA SR304426
SLC7A5 SLCs contribute to endocrine resistance in breast cancer: role of SLC7A5 (LAT1) BioRxiv, 2019 Feb siRNA SR305376
SLC8A1 Sodium-calcium exchanger 1 is the key molecule for urinary potassium excretion against acute hyperkalemia PLoS ONE, 2020 Jun siRNA SR304429