siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
SLC8B1 Na+ controls hypoxic signalling by the mitochondrial respiratory chain Nature, 2020 Jul siRNA SR504963
SLC8B1 Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria Nat Commun, 2018 Jan siRNA SR312772
SLCO2B1 Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer J. Clin. Oncol., 2015 Dec siRNA SR307748
SLIT3 Tissue-specific angiogenic and invasive properties of human neonatal thymus and bone MSCs: Role of SLIT3-ROBO1 Stem Cells Transl Med, 2020 May siRNA SR304465
SMAD3 Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3 bioRxiv, 2018 Jul siRNA SR414095
SMAD3 Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus Proc. Natl. Acad. Sci. U.S.A, 2016 Aug siRNA SR320898
SMAD4 Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts Oncotarget, 2018 Jan siRNA SR320899
SMAD7 YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts Cell Commun. Signal, 2018 Apr siRNA SR302771
Smarca1 Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation Nat Commun, 2014 Jun siRNA SR421862
SMN1 Spinal astrocyte dysfunction drives motor neuron loss in late-onset spinal muscular atrophy Acta Neuropathologica, 2023 Mar siRNA SR304480
SMN1 SMN affects membrane remodelling and anchoring of the protein synthesis machinery J. Cell. Sci., 2016 Jan siRNA SR304480
Smpd3 Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue Cell metabolism, 2022 Apr siRNA SR427338
SMURF1 SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis Cartilage, 2020 Oct siRNA SR311389
SMURF2 The E3 Ubiquitin Ligase SMAD Ubiquitination Regulatory Factor 2 Negatively Regulates Krüppel-like Factor 5 Protein J. Biol. Chem., Nov 2011; 286: 40354 - 40364., 2011 Nov siRNA SR312096
SMURF2 TRB3 interacts with SMAD3 promoting tumor cell migration and invasion J. Cell Sci., Oct 2011; 124: 3235 - 3246., 2011 Oct siRNA SR312096
SNAI1 Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion Cell adhesion & migration, 2021 Dec siRNA SR304489
SNAI1 Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions The Journal of steroid biochemistry and molecular biology, 2021 Jun siRNA SR304489
SNAI2 A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition Cell Death Differ., 2017 May siRNA SR304468
SNCB Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro Cell Transplant, 2018 Jan siRNA SR514215
SNW1 RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells Int. J. Biochem. Cell Biol., 2017 Jul siRNA SR307894
Snx17 SNX17 protects the heart from doxorubicin-induced cardiotoxicity by modulating LMOD2 degradation. Pharmacological research, 2022 Feb siRNA SR515149
Socs1 Breast cancer cell–derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function The Journal of Clinical Investigation, 2022 Oct siRNA SR426031
SOCS2 Suppressor of cytokine signaling 2 is induced in Huntington\'s disease and involved in autophagy Biochemical and biophysical research communications, 2021 Apr siRNA SR405008
SOCS3 Suppressor of Cytokine Signaling 1 Is a Positive Regulator of TGF-ß-Induced Prostaglandin Production in Human Follicular Dendritic Cell-like Cells J. Immunol., 2015 May siRNA SR305948
SOCS5 Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5 Sci Rep, 2016 Jun siRNA SR306430
SORT1 Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion Breast Cancer Res., 2018 Nov siRNA SR304211
SOST Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness JCI Insight, 2019 Apr siRNA SR309452
SOX18 Sry-type HMG box 18 contributes to the differentiation of bone marrow-derived mesenchymal stem cells to endothelial cells Differentiation, 2015 Apr siRNA SR310056
SOX2 CHI3L1 results in poor outcome of ovarian cancer by promoting properties of stem-like cells Endocr. Relat. Cancer, 2018 Aug siRNA SR304528
SOX2 Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation Sci Rep, 2016 Jun siRNA SR304528
SOX2 CEACAM1 Promotes Melanoma Cell Growth through Sox-2 Neoplasia, 2014 Jun siRNA SR304528
SOX3 Overexpression of microRNA-194 suppresses the epithelial-mesenchymal transition in targeting stem cell transcription factor Sox3 in endometrial carcinoma stem cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017 Jun siRNA SR304529
SOX9 Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis Oncogene, 2020 Dec siRNA SR304532
SOX9 SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells Oncotarget, 2016 May siRNA SR304532
SOX9 Sry-type HMG box 18 contributes to the differentiation of bone marrow-derived mesenchymal stem cells to endothelial cells Differentiation, 2015 Apr siRNA SR304532
SOX9 In vitro osteogenic potential of human bone marrow derived MSCs is predicted by Runx2/Sox9 Ratio Tissue Eng Part A July 2014, 2014 Jul siRNA SR304532
SP1 Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus J Huntingtons Dis, 2018 Aug siRNA SR304537
SP1 MicroRNA-29b Regulates Ethanol-induced Neuronal Apoptosis in the Developing Cerebellum through Sp1/Rax/PKR J. Biol. Chem., Feb 2014., 2014 Feb siRNA SR420087
SP1 A possible gene silencing mechanism: Hypermethylation of the Keap1 promoter abrogates binding of the transcription factor Sp1 in lung cancer cells Biochem Biophys Res Commun. 2012 Nov 9;428(1):80-5, 2012 Nov siRNA SR304537
SP6 Pannexin 3 regulates skin development via Epiprofin Scientific Reports, 2021 Jan siRNA SR312895
SPARC Glioblastoma-secreted soluble CD44 activates tau pathology in the brain Exp. Mol. Med., 2018 Apr siRNA SR408816
SPARC Enhancing Docetaxel Delivery to Multidrug-Resistant Cancer Cells with Albumin-Coated Nanocrystals Mol. Pharm., 2018 Jan siRNA SR321872
SPIC Spi-C positively regulates RANKL-mediated osteoclast differentiation and function Exp. Mol. Med., 2020 Apr siRNA SR406758
Spns2 Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs J. Clin. Invest., 2014 Oct siRNA SR417168
SPP1 Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β-catenin signaling Oncology letters, 2021 May siRNA SR304557
Spry1 Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer Mol. Carcinog., 2016 Sep siRNA SR405932
SPRY1 Atypical role of sprouty in p21 dependent inhibition of cell proliferation in colorectal cancer Mol. Carcinog., 2015 Aug siRNA SR306938
SPRY2 microRNA-23a promotes cell growth and metastasis in gastric cancer via targeting SPRY2-mediated ERK signaling Oncol Lett, 2018 Jun siRNA SR306939
SPSB1 SPSB1, a Novel Negative Regulator of the TGF-ß Signaling Pathway Targeting the Type II Receptor J. Biol. Chem., 2015 Jun siRNA SR312825
SPTBN1 IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation J. Exp. Med., Mar 2013; 210: 517 - 534., 2013 Mar siRNA SR304571