shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
RPS6KA1 Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway Oncotarget, 2016 Jul shRNA TR320517
RPS6KA3 Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration Biochim. Biophys. Acta July 2014, 2014 Jul shRNA TG320519
Rps6ka4 miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy Nat Commun, 2016 Jun shRNA TR503222
Rps6ka5 Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes Epigenetics Chromatin, 2016 Nov shRNA TR504795
RPS6KB1 Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade Cell death and differentiation, 2021 Feb shRNA TF320520
Rps6kb1 S6K directly phosphorylates IRS-1 on Ser270 to promote insulin resistance in response to TNF-alpha signaling through IKK2 J. Biol. Chem. published 24 October 2008, 10.1074/jbc.M806480200, 2008 Oct shRNA TR504743
RSU1 Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis PLoS One. 2013 Sep 18;8(9):e74625, 2013 Sep shRNA RG203334
Runx1 Neural EGFL like 1 as a potential pro-chondrogenic, anti-inflammatory dual-functional disease-modifying osteoarthritis drug Biomaterials, 2021 Jan shRNA TL500282
RUNX1 MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5 Cell. Signal., 2014 Oct shRNA TG309685
Runx2 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell reports, 2019 Aug shRNA TF510502
Runx2 Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3–Mediated Indian Hedgehog Signaling The American Journal of Pathology, 2019 Feb shRNA TF510502
Runx2 Nfatc1 Is a Functional Transcriptional Factor Mediating Nell-1-Induced Runx3 Upregulation in Chondrocytes International Journal of Molecular Sciences, 2018 Jan shRNA TF510502
RUNX2 RUNX2 in subtype specific breast cancer and mammary gland differentiation Dis Model Mech, 2014 Mar shRNA TG309683
RUNX3 IL-4 prevents adenosine-mediated immunoregulation by inhibiting CD39 expression. JCI insight, 2022 Jun shRNA TL309682
RUNX3 The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age Cell reports, 2021 Nov shRNA TL309682
Runx3 Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3–Mediated Indian Hedgehog Signaling The American Journal of Pathology, 2019 Feb shRNA TG500285
Rxra Retinoid-X-Receptors (a/ß) in Melanocytes Modulate Innate Immune Responses and Differentially Regulate Cell Survival following UV Irradiation PLoS Genet., 2014 May shRNA TG501955
Rxrb Retinoid-X-Receptors (a/ß) in Melanocytes Modulate Innate Immune Responses and Differentially Regulate Cell Survival following UV Irradiation PLoS Genet., 2014 May shRNA TF501956
S100A4 S100A4 is activated by RhoA and catalyzes the polymerization of non-muscle myosin, adhesion complex assembly and contraction in airway smooth muscle J. Physiol. (Lond.) 2020, 2020 Aug shRNA TG309668
S100a8 Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis International Journal of Molecular Sciences, 2021 Jan shRNA TL712179
S100B S100B Promotes Glioma Growth through Chemoattraction of Myeloid-Derived Macrophages Clin. Cancer Res., Jul 2013; 19: 3764 - 3775., 2013 Jul shRNA TG309665
S1PR1 Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways Blood, Aug 2008; 112: 1129 - 1138., 2008 Aug shRNA TR313301
S1PR3 Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways Blood, Jun 2008; 10.1182/blood-2007-11-125203., 2008 Jun shRNA TR313299
SAR1A Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience Genome Med, 2017 Nov shRNA TG301838
SATB1 SATB1 Knockdown Inhibits Proliferation and Invasion and Decreases Chemoradiation Resistance in Nasopharyngeal Carcinoma Cells by Reversing EMT and Suppressing MMP-9 Int J Med Sci., 2021 Jan shRNA TG309643
SATB1 Silencing SATB1 influences cell invasion, migration, proliferation, and drug resistance in nasopharyngeal carcinoma Int J Clin Exp Pathol, 2014 Apr shRNA TG309643
SATB2 Role of miR-31 and SATB2 in arsenic-induced malignant BEAS-2B cell transformation Mol. Carcinog., 2018 Mar shRNA TG301833
SATB2 Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells PLoS ONE, 2016 May shRNA TG301833
SATB2 SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells Toxicol. Appl. Pharmacol., 2016 Jan shRNA TG301833
SAV1 Salvador Protein Is a Tumor Suppressor Effector of RASSF1A with Hippo Pathway-independent Functions J. Biol. Chem., May 2011; 286: 18483 - 18491, 2011 May shRNA TR301832
SCARB1 Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth Cell. Microbiol., 2015 Sep shRNA TG309633
SCG3 Carboxypeptidase E and Secretogranin III coordinately facilitate efficient sorting of pro-opiomelanocortin to the regulated secretory pathway in AtT20 cells Molecular Endocrinology Dec2015, 2015 Dec shRNA TR516044
SCIMP SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling Mol. Cell. Biol., Nov 2011; 31: 4550 - 4562., 2011 Nov shRNA
SCPEP1 Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1 PLoS Genet., 2014 Feb shRNA TF505007
Scrambled Control Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules Redox biology, 2021 Jun shRNA TR30013
Scrambled Control Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism International Journal of Molecular Sciences, 2021 May shRNA TR30012
Scrambled Control NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl- concentration Immunology, 2021 Apr shRNA TR30013
Scrambled Control Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein Viruses, 2021 Mar shRNA TR30013
Scrambled Control Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression Scientific reports, 2021 Mar shRNA TR30012
Scrambled Control Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs Cells, 2021 Jan shRNA TR30013
Scrambled Control Cell dynamics in Hertwig\'s epithelial root sheath are regulated by β-catenin activity during tooth root development Journal of cellular physiology, 2020 Dec shRNA TR30013
Scrambled Control Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells J Cell Physiol, 2020 Oct shRNA TR30013
Scrambled Control USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway Proc Natl Acad Sci U S A, 2020 Oct shRNA TR30015
Scrambled Control Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma J. Dermatol. Sci., 2020 Sep shRNA TR30021
Scrambled Control TGFβ-Induced Phosphorylation of Usp9X Stabilizes Ankyrin-G and Regulates Dendritic Spine Maintenance SSRN Journal, 2020 Jan shRNA TR30015
Scrambled Control Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction Nat Commun, 2018 Oct shRNA TR30015
Scrambled Control Imbalance of a KLF4-miR-7 auto-regulatory feedback loop promotes prostate cancer cell growth by impairing microRNA processing Am J Cancer Res, 2018 Feb shRNA TR30013
Scrambled Control Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience Genome Med, 2017 Nov shRNA TR30013
Scrambled shRNA Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology Nat Commun, 2018 Jan shRNA TR30012
Scrambled shRNA Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural plasticity and spatial memory Antioxid. Redox Signal., 2018 Jan shRNA TR30013