shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
scrambled shRNA Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural plasticity and spatial memory Antioxid. Redox Signal., 2018 Jan shRNA TR30015
SCRT2 Scratch2 Modulates Neurogenesis and Cell Migration Through Antagonism of bHLH Proteins in the Developing Neocortex Cereb Cortex, Nov 2012; 10.1093/cercor/bhs356., 2012 Nov shRNA TG307416
SDC2 Binding of Y-P30 to Syndecan 2/3 Regulates the Nuclear Localization of CASK PLoS ONE, Feb 2014., 2014 Feb shRNA TR309597
SDC3 Binding of Y-P30 to Syndecan 2/3 Regulates the Nuclear Localization of CASK PLoS ONE, Feb 2014., 2014 Feb shRNA TR309596
SDC4 Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution Int J Mol Sci, 2020 Jan shRNA TR513122
SDC4 Syndecan-4 influences mammalian myoblast proliferation by modulating myostatin signalling and G1/S transition FEBS Lett., 2018 Aug shRNA TR513122
Sdcbp Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells Frontiers in Pharmacology, 2015 Oct shRNA TG512166
SDHA Complex I and II are required for normal mitochondrial Ca2+ homeostasis Mitochondrion, 2019 Jul shRNA TR315539
SELENOP Selenoprotein P neutralizes lipopolysaccharide and participates in hepatic cell endoplasmic reticulum stress response FEBS Lett, 2016 Dec shRNA TR309547
SEMA6D The Plexin-A1 Receptor Activates Vascular Endothelial Growth Factor-Receptor 2 and Nuclear Factor-B to Mediate Survival and Anchorage-Independent Growth of Malignant Mesothelioma Cells Cancer Res., Feb 2009; 69: 1485 - 1493, 2009 Feb shRNA TR301776
SENP3 Increased SUMO-2/3-ylation mediated by SENP3 degradation is protective against cadmium-induced caspase 3-dependent cytotoxicity J Toxicol Sci, 2017 Jul shRNA TG505363
SENP3 Protective effect of SENP3-mediated SUMOylation against cadmium toxicity J Toxicol Sci, 2017 Mar shRNA TG701864
Senp5 Synaptic localization of the SUMOylation-regulating protease SENP5 in the adult mouse brain. The Journal of comparative neurology, 2019 Jun shRNA TL508307
SENP7 Novel SUMO-Protease SENP7S Regulates ß-catenin Signaling and Mammary Epithelial Cell Transformation Sci Rep, 2017 Apr shRNA TR301771
Septin2 Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion J. Cell Biol., 2016 Aug shRNA TG515794
Septin5 Mapping axon initial segment structure and function by multiplexed proximity biotinylation Nature Communications, 2020 Jan shRNA TL501695
Septin6 Mapping axon initial segment structure and function by multiplexed proximity biotinylation Nature Communications, 2020 Jan shRNA TL509453
Serpina1 Endothelial-mesenchymal transition in atherosclerotic lesion calcification Atherosclerosis, 2016 Sep shRNA TR710718
Serpinb2 Depletion of ID3 enhances mesenchymal stem cells therapy by targeting BMP4 in Sjögren’s syndrome Cell Death & Disease, 2020 Mar shRNA TL710486
SERPINB2 PNAS Plus: TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2 PNAS, Jan 2012; 109: E177 - E186., 2012 Jan shRNA TR309533
SERPINB9 Anti-Apoptotic Gene Delivery with cyclo-(d-Trp-Tyr) Peptide Nanotube via Eye Drop Following Corneal Epithelial Debridement Pharmaceutics, 2015 Jul shRNA TF309527
SERPINE1 Serpine 1 induces alveolar type II cell senescence through activating p53-p21-Rb pathway in fibrotic lung disease Aging Cell, 2017 Jul shRNA TF709263
SESN2 HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells Cell Death Dis, 2018 Sep shRNA TG301755
SETD7 SET9-Mediated Regulation of TGF-ß Signaling Links Protein Methylation to Pulmonary Fibrosis Cell Rep, 2016 Jun shRNA TG301748
SETMAR Metnase mediates chromosome decatenation in acute leukemia cells Blood, May 2009; 10.1182/blood-2008-08-175760, 2009 May shRNA TR309513
Sf1 DNA damage causes rapid accumulation of phosphoinositides for ATR signaling Nat Commun, 2017 Dec shRNA TF516038
SFRP5 Secreted frizzled-related protein 5 protects against oxidative stress-induced apoptosis in human aortic endothelial cells via downregulation of Bax J. Biochem. Mol. Toxicol., 2017 Aug shRNA TR309497
SFXN4 Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer Scientific Reports, 2022 Nov shRNA TL301736
SGK1 p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis Aging (Albany NY) 2019, 2019 Feb shRNA TG502013
Sgms1 The suppression of ghrelin signaling mitigates age-associated thermogenic impairment Aging (Albany NY), 2014 Dec shRNA TG506246
SGTA Tumor suppressor REIC/Dkk‑3 and its interacting protein SGTA inhibit glucocorticoid receptor to nuclear transport Exp Ther Med, 2020 May shRNA TG309472
sh-Luc(in vivo application) RNA interference-mediated in vivo silencing of FasL as a strategy for the enhancement of DNA vaccine potency Human Gene Therapy. August 2008, 19(8): 763-773, 2008 Aug shRNA
SH3BGRL SH3BGRL confers innate drug resistance in breast cancer by stabilizing HER2 activation on cell membrane J. Exp. Clin. Cancer Res., 2020 May shRNA TG309466
SH3BGRL SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia Leuk. Lymphoma, 2017 Jul shRNA TG309466
SH3GL2 SH3BGRL confers innate drug resistance in breast cancer by stabilizing HER2 activation on cell membrane Journal of Experimental & Clinical Cancer Research : CR, 2020 May shRNA TG309461
SH3GL2 SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. Leukemia & lymphoma, 2019 Jan shRNA TG309461
SH3GL2 Dual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humans Oncogene, 2016 Jun shRNA TG309461
shank3 SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism Molecular Psychiatry (24 May 2011) doi:10.1038/mp.2011.57 Original Article, 2011 May shRNA TR320871
shRNA Human ß-defensin-2 enhances IFN-{gamma} and IL-10 production and suppresses IL-17 production in T cells J. Leukoc. Biol., Jun 2011; 89: 935 - 944, 2011 Jun shRNA
shRNA GPR103b Functions in the Peripheral Regulation of Adipogenesis Mol. Endocrinol., Aug 2010; 24: 1615 - 1625, 2010 Aug shRNA
shRNA A New Type of Membrane Raft-Like Microdomains and Their Possible Involvement in TCR Signaling J. Immunol., Apr 2010; 184: 3689 - 3696, 2010 Apr shRNA
shRNA TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-B J. Leukoc. Biol., Mar 2008; 83: 702 - 707, 2008 Mar shRNA
SIGLECE Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production J. Immunol., Dec 2009; 183: 7703 - 7709, 2009 Dec shRNA TR512042
SIGMAR1 SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism J. Pharmacol. Sci., 2019 Jan shRNA TG311012
SIGMAR1 Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP 3 -Evoked Ca 2+ Signals through Sigma-1 Receptors Cell Reports, 2019 Jan shRNA TF311012
Sigmar1 Cocaine Inhibits Store-Operated Ca 2+ Entry in Brain Microvascular Endothelial Cells: Critical Role for Sigma-1 Receptors The Biochemical journal, 2015 Oct shRNA TF711128
SIGMAR1 Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances Cell Death Dis, 2014 Jun shRNA TF311012
SIGMAR1 Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis Hum. Mol. Genet., Apr 2013; 22: 1581 - 1600., 2013 Apr shRNA TG311012
SIRT1 Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a Mol. Cancer, 2018 Jun shRNA TG309433
SIRT1 Chronic sun exposure is associated with distinct histone acetylation changes in human skin Br. J. Dermatol.2017, 2017 Nov shRNA TG309433