siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
TFDP1 Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma PLoS ONE, 2015 Dec siRNA SR304794
TFDP3 TFDP3 confers chemoresistance in minimal residual disease within childhood T-cell acute lymphoblastic leukemia Oncotarget, 2017 Jan siRNA SR309663
THAP11 Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression Cell, 2019 Apr siRNA SR311427
TICAM1 TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages Cell Rep, 2020 Mar siRNA SR315629
TIGAR Down-regulation of TFAM increases the sensitivity of tumour cells to radiation via p53/TIGAR signalling pathway J. Cell. Mol. Med., 2019 May siRNA SR311348
TIMP2 TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells BMC Cancer, 2020 Oct siRNA SR304838
TINCR miR‑589‑3p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R Int. J. Mol. Med., 2020 Sep siRNA SR316884
Tissue Lysate Endothelial Nitric-oxide Synthase (eNOS) Is Activated through G-protein-coupled Receptor Kinase-interacting Protein 1 (GIT1) Tyrosine Phosphorylation and Src Protein J. Biol. Chem., 2014 Jun siRNA SR30004
TJP1 Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family Molecular Neurobiology, 2023 May siRNA SR322042
TLE3 Differential Regulation of TLE3 in Sertoli Cells of the Testes during Postnatal Development Cells, 2019 Sep siRNA SR420092
TLR2 Complement Component C3 Promotes Cerebral Ischemia/Reperfusion Injury Mediated by TLR2/NFκB Activation in Diabetic Mice Neurochem. Res., 2018 Jun siRNA SR322049
TLR4 Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway Biomedicines, 2020 Oct siRNA SR322051
TLR4 MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress Cells, 2020 Jul siRNA SR322051
TLR4 The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways Int J Mol Sci, 2019 Sep siRNA SR322051
TLR4 TNF-α in Combination with Palmitate Enhances IL-8 Production via The MyD88- Independent TLR4 Signaling Pathway: Potential Relevance to Metabolic Inflammation Int J Mol Sci, 2019 Aug siRNA SR322051
TLR4 MIP-1α Induction by Palmitate in the Human Monocytic Cells Implicates TLR4 Signaling Mechanism Cell. Physiol. Biochem., 2019 Feb siRNA SR322051
TLR4 Palmitate Activates CCL4 Expression in Human Monocytic Cells via TLR4/MyD88 Dependent Activation of NF-κB/MAPK/ PI3K Signaling Systems Cell. Physiol. Biochem., 2018 Apr siRNA SR322051
TLR4 The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation J. Immunol., 2018 Apr siRNA SR322051
TLR4 Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia Brain Behav. Immun., 2017 Mar siRNA SR420542
TLR4 Palmitate-Induced MMP-9 Expression in the Human Monocytic Cells is Mediated through the TLR4-MyD88 Dependent Mechanism Cell. Physiol. Biochem., 2016 Aug siRNA SR304858
TLR9 Toll-Like Receptor 9 Signaling Regulates Tissue Factor and Tissue Factor Pathway Inhibitor Expression in Human Endothelial Cells and Coagulation in Mice Critical Care Medicine, 2015 Jun siRNA SR310036
TLR9 HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon PLoS Pathog., 2014 May siRNA SR310036
TM4SF1 Transmembrane-4 L-six family member-1 (TM4SF1) promotes non-small cell lung cancer proliferation, invasion and chemo-resistance through regulating the DDR1/Akt/ERK-mTOR axis Respir. Res., 2019 May siRNA SR320889
TMBIM6 An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar J. Cell. Physiol., 2019 Apr siRNA SR406571
TMEM97 NO1, a New Sigma 2 Receptor/TMEM97 Fluorescent Ligand, Downregulates SOCE and Promotes Apoptosis in the Triple Negative Breast Cancer Cell Lines Cancers (Basel) 2020, 2020 Jan siRNA SR309105
TMPO Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus Nat Commun, 2020 May siRNA SR304871
TNF Transmembrane TNF- α Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy Journal of the American Society of Nephrology : JASN, 2017 Mar siRNA SR322065
TNF Transmembrane TNF-a Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy J. Am. Soc. Nephrol, 2016 Nov siRNA SR304877
TNFAIP6 TSG-6 Controls Transcription and Activation of Matrix Metalloproteinase 1 in Conjunctivochalasis Investigative Ophthalmology & Visual Science, 2012 Sep siRNA SR304882
TNFRSF11B Androgen deprivation therapy sensitizes triple negative breast cancer cells to immune-mediated lysis through androgen receptor independent modulation of osteoprotegerin Oncotarget, 2016 Apr siRNA SR303289
TNFRSF1A A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis Cell Death Differ., Jan 2014., 2014 Jan siRNA SR304883
TNFRSF1A Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex The Journal of Biological Chemistry, 2012 Apr siRNA SR304883
TNFSF4 Recombinant OX40 attenuates neuronal apoptosis through OX40-OX40L/PI3K/AKT signaling pathway following subarachnoid hemorrhage in rats Exp. Neurol., 2020 Jan siRNA SR500332
TOP1 MUS81 cleaves TOP1-derived lesions and other DNA–protein cross-links BMC Biology, 2023 May siRNA SR322073
TOP1 Cellular DNA topoisomerases are required for the synthesis of hepatitis B virus covalently closed circular DNA J. Virol., 2019 Mar siRNA SR304897
TOP2A TOP2A Promotes Cell Migration, Invasion and Epithelial–Mesenchymal Transition in Cervical Cancer via Activating the PI3K/AKT Signaling Cancer Management and Research, 2020 May siRNA SR322074
TOP2A Cellular DNA topoisomerases are required for the synthesis of hepatitis B virus covalently closed circular DNA J. Virol., 2019 Mar siRNA SR322074
Top2a Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia Oncotarget, 2016 Oct siRNA SR422969
TOP2B Cellular DNA topoisomerases are required for the synthesis of hepatitis B virus covalently closed circular DNA J. Virol., 2019 Mar siRNA SR304899
TOX TOX expression and role in CTCL J Eur Acad Dermatol Venereol, 2016 Sep siRNA SR306524
TP53 Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus J Huntingtons Dis, 2018 Aug siRNA SR322075
TP53 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability PLoS ONE, 2018 Mar siRNA SR322075
TP53 RASSF10 is Epigenetically Inactivated and Suppresses Cell Proliferation and Induces Cell Apoptosis by Activating the p53 Signalling Pathway in Papillary Thyroid Carcinoma Cancer Cell. Physiol. Biochem, 2017 Mar siRNA SR322075
TP53 Multisite aggregation of p53 and implications for drug rescue Proc. Natl. Acad. Sci. U.S.A, 2017 Mar siRNA SR413083
TP53 Very Low Doses of Ionizing Radiation and Redox Associated Modifiers Affect Survivin-Associated Changes in Radiation Sensitivity Free Radic. Biol. Med., 2016 Jul siRNA SR413083
TP63 Multisite aggregation of p53 and implications for drug rescue Proc. Natl. Acad. Sci. U.S.A, 2017 Mar siRNA SR305666
TP73 Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status Leuk. Lymphoma, 2016 Apr siRNA SR304904
Tra2b Transformer 2 beta homolog (Drosophila) (TRA2B) regulates Protein Kinase C deltaI (PKCdI) splice variant expression during 3T3L1 pre-adipocyte cell cycle J. Biol. Chem., 2014 Sep siRNA SR408282
Traf2 Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research, 2022 Nov siRNA SR505994
TRAF3 The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development Sci Signal, 2015 Sep siRNA SR304928