shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
AIFM1 Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression Blood, Mar 2011; 117: 2891 - 2900, 2011 Mar shRNA TR302572
AIM2 Francisella tularensis Reveals a Disparity between Human and Mouse NLRP3 Inflammasome Activation J. Biol. Chem., Nov 2011; 286: 39033 - 39042., 2011 Nov shRNA TR314876
AKIRIN2 A critical role for the nuclear protein Akirin2 in the formation of mammalian muscle in vivo Genesis, 2019 Feb shRNA TF805514
AKT1 Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells Br. J. Cancer, 2015 May shRNA TR320260
Alas1 Heterochromatin protein (HP)1γ is not only in the nucleus but also in the cytoplasm interacting with actin in both cell compartments Biochim. Biophys. Acta, 2017 Dec shRNA TG500071
ALDH1B1 Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma Pancreas, 2016 Jan shRNA TF314844
ALDH1B1 ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/ß-Catenin, Notch and PI3K/Akt Signaling Pathways PLoS ONE, 2015 May shRNA TF314844
ALKBH3 Human ALKBH3-induced m1A demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells Biochim Biophys Acta Gene Regul Mech, 2018 Oct shRNA TR306757
ALOX12 Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection Proc. Natl. Acad. Sci. U.S.A., 2014 Oct shRNA TR314824
ALOX15 Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion Cancer Prevention Research, Dec 2011; 4: 1961 - 1972., 2011 Dec shRNA TR314822
AMER1 Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression Nat Commun, 2019 Jan shRNA TG307603
AMPH AMPH-1 is a tumor suppressor of lung cancer by inhibiting Ras-Raf-MEK-ERK signal pathway Lasers Med Sci, 2018 Aug shRNA TR306724
ANG2 Angiopoietin-2 Regulates Cortical Neurogenesis in the Developing Telencephalon Cereb Cortex, Jul 2011; 21: 1695 - 1702., 2011 Sep shRNA TR500092
ANGPT1 Oct4-dependent FoxC1 Activation Improves the Survival and Neovascularization of Mesenchymal Stem Cells under Myocardial Ischemia Research Square, 2021 Mar shRNA TR711949
Angpt2 Angiopoietin-2 Regulates Cortical Neurogenesis in the Developing Telencephalon Cereb Cortex, Dec 2010; 10.1093/cercor/bhq243, 2010 Dec shRNA TR514004
Angptl4 Mechanisms involved in biological behavior changes associated with Angptl4 expression in colon cancer cell lines. Oncology reports, 2012 Jul shRNA TL713738
ANK Antagonistic interactions between osterix and pyrophosphate during cementum formation Bone, 2019 May shRNA TR500093
ANO5 Deficiency of Anoctamin 5/TMEM16E causes nuclear positioning defect and impairs Ca2+ signaling of differentiated C2C12 myotubes Korean J. Physiol. Pharmacol., 2019 Nov shRNA TG509067
Ano6 Fusion Stage of HIV-1 Entry Depends on Virus-Induced Cell Surface Exposure of Phosphatidylserine Cell Host Microbe, 2017 Jul shRNA TF511035
Ano6 Calcium-dependent phospholipid scrambling by TMEM16F Nature 468, 834-838 (24 November 2010) doi:10.1038/nature09583 Letter, 2010 Nov shRNA TR511035
ANXA1 The Effect of Annexin A1 as a Potential New Therapeutic Target on Neuronal Damage by Activated Microglia Molecules and cells, 2021 Apr shRNA TG513843
ANXA1 Hydrodynamic stress stimulates growth of cell clusters via the ANXA1/PI3K/AKT axis in colorectal cancer Sci Rep, 2019 Dec shRNA TR314775
ANXA1 Differential expression of ANXA1 in benign human gastrointestinal tissues and cancers BMC Cancer July 2014, 2014 Jul shRNA TR314775
Anxa2 Annexin A2 Enhances Complement Activation by Inhibiting Factor H J. Immunol., 2016 Feb shRNA TF500250
ANXA2 Annexin A2 is a C-terminal PCSK9 binding protein that regulates endogenous LDL receptor levels J. Biol. Chem., Sep 2008; 10.1074/jbc.M805971200., 2008 Sep shRNA TR314772
ANXA2R The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway PLoS ONE, 2016 Mar shRNA TG315286
ANXA6 Balancing functions of annexin A6 maintain equilibrium between hypertrophy and apoptosis in cardiomyocytes Cell Death Dis, 2015 Sep shRNA TG314768
ANXA6 Cytosolic dynamics of annexin A6 triggers feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes J. Biol. Chem., Jan 2014., 2014 Jan shRNA TG314768
AP2A1 Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation J. Biol. Chem., Mar 2012; 287: 9429 - 9440., 2012 Jan shRNA TR314754
AP2M1 Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 J. Biol. Chem., 2019 Oct shRNA TG712191
AP2M1 Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2 BioRxiv, 2019 Mar shRNA TG712191
APBB1 A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer\'s disease pathologies Brain : a journal of neurology, 2021 Apr shRNA TG306652
APBB1 Fe65 Suppresses Breast Cancer Cell Migration and Invasion through Tip60 Mediated Cortactin Acetylation Sci Rep, 2015 Jul shRNA TG306652
APCS Complex formation with Pentraxin-2 regulates Factor X plasma levels and macrophage interactions Blood, 2017 Feb shRNA TR501968
APOBEC3 Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy Nature communications, 2021 Mar shRNA TG505334
APOBEC3 APOBEC3 mediates resistance to oncolytic viral therapy Molecular Therapy - Oncolytics, 2018 Aug shRNA TR505334
APOE Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity Front Immunol, 2019 Jun shRNA TG500118
APOE Apolipoprotein E3 (ApoE3) but Not ApoE4 Protects against Synaptic Loss through Increased Expression of Protein Kinase C J. Biol. Chem., May 2012; 287: 15947 - 15958., 2012 May shRNA TR314721
APRT Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells PLoS ONE, 2015 Nov shRNA TG320095
Aqp1 Aquaporin 1 is Important for Maintaining Secretory Granule Biogenesis in Endocrine Cells Mol. Endocrinol., Aug 2008; 22: 1924 - 1934, 2008 Aug shRNA TR500121
AQP3 Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA‑MB‑231 breast cancer cell line Oncol Lett, 2018 May shRNA TF314712
AR Stromal Hyaluronan Interaction with Epithelial CD44 Variants Promotes Prostate Cancer Invasiveness by Augmenting Expression and Function of Hepatocyte Growth Factor and Androgen Receptor J. Biol. Chem., Jun 2010; 285: 19821 - 19832, 2010 Jun shRNA TR320265
ARF6 A critical role of Arf6 in the response of commissural axons to Slit Development, 2019 Jan shRNA TR500130
Arf6 Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse Elife, 2016 Jan shRNA TF710999
Arf6 Antagonistic Functions of Dishevelleds Regulate Frizzled3 Endocytosis via Filopodia Tips in Wnt-Mediated Growth Cone Guidance J. Neurosci. Dec 2013., 2013 Dec shRNA TG500130
ARHGAP15 Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway Cancer Sci, 2017 Jan shRNA TR306620
ARHGDIA Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression Nat Commun, 2019 Jan shRNA TG314680
ARHGEF17 Phosphorylation of Cdc42 Effector Protein-4 (CEP4) by Protein Kinase C Promotes Motility of Human Breast Cells J. Biol. Chem., 2014 Aug shRNA TG314673
ARHGEF9 RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABAA receptors PLoS Genet.2017, 2017 Oct shRNA TF517554
ARID1A A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment Oncotarget, 2016 Aug shRNA TG306603