shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
SIRT1 SIRT1 promotes metastasis of human osteosarcoma cells Oncotarget, 2016 Nov shRNA TG309433
SIRT2 Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism International Journal of Molecular Sciences, 2021 May shRNA TR301692
SIRT2 SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib Cancers (Basel) 2019, 2019 May shRNA TR301692
SIRT2 Sirt2 Regulates Radiation-Induced Injury Radiat. Res., 2019 Mar shRNA TG301692
Sirt2 SIRT2 Interacts with β-catenin to Inhibit Wnt Signaling Output in Response to Radiation-Induced Stress Molecular cancer research : MCR, 2015 Sep shRNA TL503462
SIRT3 GATA3 ameliorates melanocyte injuries in vitiligo through SIRT3-mediated HMGB1 deacetylation. The Journal of dermatology, 2023 Apr shRNA TG309432
SIRT3 Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells Oncogene, 2019 Nov shRNA TR309432
SIRT3 Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer. Journal of cellular physiology, 2019 Sep shRNA TR309432
SIRT3 Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells bioRxiv, 2019 Jun shRNA TR309432
SIRT3 Sirtuin 3 silencing impairs mitochondrial biogenesis and metabolism in colon cancer cells Am. J. Physiol., Cell Physiol., 2019 Jun shRNA TR309432
SIRT7 SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair EMBO J., 2016 May shRNA TR301690
SIX1 HPV16-transformed human keratinocytes depend on SIX1 expression for proliferation and HPV E6/E7 gene expression Virology, 2019 Aug shRNA TG309429
SKP2 Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma Sci Rep, 2018 Sep shRNA TG301684
SLAMF1 SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response J. Clin. Invest., 2016 Jan shRNA TG309422
SLC16A1 Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition. Cell reports, 2022 Feb shRNA TL309405
SLC16A1 Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer Cell Rep, 2020 Jun shRNA TR309405
SLC17A5 From the Cover: Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane PNAS, Aug 2012; 109: 13434 - 13439., 2012 Aug shRNA TR309394
SLC17A5 Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane PNAS, Jul 2012; 10.1073/pnas.1116633109., 2012 Jul shRNA TR309394
SLC1A3 Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I Diabetes, 2017 Jan shRNA TR515328
SLC22A18 Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells Pharm. Res., 2019 Jan shRNA TR309377
SLC22A18 Involvement of an orphan transporter, SLC22A18, in cell growth and drug resistance of human breast cancer MCF7 cells J Pharm Sci, 2018 Aug shRNA TR309377
Slc22a2 The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus eLife, 2022 Apr shRNA TL517269
SLC25A1 SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker Oncotarget, 2014 Mar shRNA TG316728
SLC25A1 The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis Oncotarget, 2012 Oct shRNA TG316728
SLC26A9 Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in Tp53 Environmental Health Perspectives, 2022 Jan shRNA TR301620
SLC29A1 SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia Cancer Chemother. Pharmacol., 2016 Jul shRNA TG309346
SLC2A4 GLUT4 Mobilization Supports Energetic Demands of Active Synapses Neuron, 2017 Jan shRNA TR709372
Slc30a8 Down-Regulation of ZnT8 Expression in INS-1 Rat Pancreatic Beta Cells Reduces Insulin Content and Glucose-Inducible Insulin Secretion PLoS ONE 4(5):e5679, 2009, 2009 May shRNA TR708553
SLC35A2 Aberrant Expression of Solute Carrier Family 35 Member A2 Correlates With Tumor Progression in Breast Cancer In Vivo, 2023 Jan shRNA TL309328
SLC36A4 Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell, 2018 Mar shRNA TG507107
SLC39A12 Role of zinc transporter ZIP12 in susceptibility-weighted brain magnetic resonance imaging (MRI) phenotypes and mitochondrial function FASEB J., 2020 Jul shRNA TF508163
SLC39A12 Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12) PNAS, Jun 2013; 110: 9903 - 9908., 2013 Jun shRNA TG301572
SLC39A4 ZIP4 Regulates Pancreatic Cancer Cell Growth by Activating IL-6/STAT3 Pathway through Zinc Finger Transcription Factor CREB Clin. Cancer Res., Mar 2010; 16: 1423 - 1430, 2010 Mar shRNA TR317306
SLC39A4 Down-regulation of ZIP4 by RNA Interference Inhibits Pancreatic Cancer Growth and Increases the Survival of Nude Mice with Pancreatic Cancer Xenografts Clin. Cancer Res., Oct 2009; 15: 5993 - 6001, 2009 Sep shRNA TR317306
Slc6a15 Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility The Journal of Neuroscience, 2018 Jan shRNA TG505662
SLC7A8 Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation Cancer Cell, 2018 Mar shRNA TG502853
SLC9A3R1 Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs Cell Death Differ., 2018 Mar shRNA TF316855
SLC9A3R1 NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with ß-Arrestin Binding Mol. Pharmacol., May 2009; 75: 1189 - 1197., 2009 May shRNA TR316855
SLC9A3R1 NHERF1 Regulates Parathyroid Hormone Receptor Desensitization; Interference with -arrestin Binding Mol. Pharmacol., Feb 2009; 10.1124/mol.108.054486., 2009 Feb shRNA TR316855
SLC9A3R1 NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling J Biol Chem. 2007 Dec 14;282(50):36214-22., 2007 Dec shRNA TR316855
SLC9A3R2 Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport J. Biol. Chem., 2016 Jul shRNA TR309271
SLC9A3R2 Na/H Exchanger Regulatory Factors Control Parathyroid Hormone Receptor Signaling by Facilitating Differential Activation of G{alpha} Protein Subunits J. Biol. Chem., Aug 2010; 285: 26976 - 26986, 2010 Aug shRNA TR309271
SLK SLK-dependent activation of ERMs controls LGN-NuMA localization and spindle orientation J. Cell Biol., 2014 Jun shRNA TG320620
SMAD2 Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis Journal of molecular and cellular cardiology, 2020 Dec shRNA TR509694
Smad2 Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification Cell Death and Differentiation, 2017 Dec shRNA TL710211
SMAD2 The transcription factor GLI1 interacts with SMAD proteins to modulate TGFß-induced gene expression in a PCAF-dependent manner J. Biol. Chem. April 2014, 2014 Apr shRNA TG309255
Smad2 Response gene to complement 32 interacts with Smad3 to promote epithelial-mesenchymal transition of human renal tubular cells Am J Physiol Cell Physiol, Jun 2011; 300: C1415 - C1421, 2011 Jun shRNA TR309255
Smad3 Response gene to complement 32 interacts with Smad3 to promote epithelial-mesenchymal transition of human renal tubular cells Am J Physiol Cell Physiol, Jun 2011; 300: C1415 - C1421, 2011 Jun shRNA TR309254
SMAD4 Protein kinase CK2 activation is required for transforming growth factor β-induced epithelial-mesenchymal transition Mol Oncol, 2018 Oct shRNA TR309253
SMAD4 Loss of Trefoil Factor 2 From Pancreatic Duct Glands Promotes Formation of Intraductal Papillary Mucinous Neoplasms in Mice Gastroenterology, 2016 Aug shRNA TG309253