siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
TRAF3 The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2 Nat. Immunol. July 2014, 2014 Jul siRNA SR304928
TRAF3IP3 TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination Nat Commun, 2020 May siRNA SR312910
TRAF6 HIV-1 and HIV-2 differentially regulate NF-κB activity during the late stages of the replication cycle through BST-2/tetherin antagonism bioRxiv, 2020 May siRNA SR322090
TRAF6 RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival Cell Rep, 2018 Jul siRNA TG515356
TRAIP The TRAF-interacting protein (TRAIP) is a regulator of the spindle assembly checkpoint J. Cell. Sci., 2014 Oct siRNA SR306973
TRDMT1 RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia Nat Commun, 2018 Mar siRNA SR301245
TREM2 TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice J Neuroinflammation, 2020 May siRNA SR406200
TRIM21 The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ. International journal of molecular sciences, 2023 May siRNA SR321894
TRIM21 The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ. International journal of molecular sciences, 2023 May siRNA SR304594
TRIM21 Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells J Neuroinflammation, Feb 2014., 2014 Feb siRNA SR304594
TRIM22 TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment J. Virol., Jan 2014., 2014 Jan siRNA SR307012
TRIM28 Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy PNAS, Apr 2013; 110: 6841 - 6846., 2013 Apr siRNA TG320633
TRIM29 TRIM29 as a Novel Biomarker in Pancreatic Adenocarcinoma Disease Markers 2014 . April 2014, 2014 Apr siRNA SR308430
TRIM3 Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development Scand. J. Gastroenterol., 2015 Dec siRNA SR307227
TRIP10 Podosome formation promotes plasma membrane invagination and integrin-β3 endocytosis on a viscous RGD-membrane Commun Biol, 2020 Mar siRNA SR514456
TRIP4 ASC-1 Is a Cell Cycle Regulator Associated with Severe and Mild Forms of Myopathy Ann. Neurol., 2019 Dec siRNA SR427213
TRPC1 Inhibition of RhoA/ROCK signaling pathway ameliorates hypoxic pulmonary hypertension via HIF-1α-dependent functional TRPC channels Toxicol. Appl. Pharmacol., 2019 Mar siRNA SR420328
TRPC6 Inhibition of RhoA/ROCK signaling pathway ameliorates hypoxic pulmonary hypertension via HIF-1α-dependent functional TRPC channels Toxicol. Appl. Pharmacol., 2019 Mar siRNA SR421279
TRPC6 The TRPC6-AMPK pathway is involved in cytoskeleton reorganization and glucose uptake in podocytes bioRxiv, 2018 Mar siRNA SR506194
TRPC6 Insulin increases filtration barrier permeability via TRPC6-dependent activation of PKGIα signaling pathways Biochim. Biophys. Acta, 2017 Mar siRNA MR225311
TRPM7 TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration Nature Communications, 2021 May siRNA SR310261
TRPM7 TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration bioRxiv, 2020 Apr siRNA SR310261
TRPM7 Effects of Salivary Mg on Head and Neck Carcinoma via TRPM7 J. Dent. Res., 2018 Dec siRNA SR310261
TRPM8 Oxidant-induced increase in norepinephrine secretion from PC12 cells is dependent on TRPM8 channel-mediated intracellular calcium elevation Biochem. Biophys. Res. Commun., 2018 Oct siRNA SR511054
TRPV4 Translocation of TRPV4-PI3Kγ complexes to the plasma membrane drives myofibroblast transdifferentiation Sci Signal, 2019 Nov siRNA SR311803
TRPV4 The TRPV4-TAZ Mechanotransduction Signaling Axis in Matrix Stiffness- and TGFβ1-Induced Epithelial-Mesenchymal Transition Cel. Mol. Bioeng., 2018 Dec siRNA SR311803
TRPV4 TRPV4 Blockade Preserves the Blood-Brain Barrier by Inhibiting Stress Fiber Formation in a Rat Model of Intracerebral Hemorrhage Front Mol Neurosci, 2018 Mar siRNA SR514696
TRPV4 TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis J. Immunol., 2015 Nov siRNA SR420901
TRPV4 TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice J. Clin. Invest., 2014 Dec siRNA SR311803
TRPV6 The low PLC-δ1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity. Cell calcium, 2015 Sep siRNA SR310734
TRPV6 The low PLC-d1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity Cell Calcium, 2014 Nov siRNA SR310734
TSC1 PP2AC Level Determines Differential Programing of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer EBioMedicine, 2015 Nov siRNA SR304945
TSC2 PP2AC Level Determines Differential Programing of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer EBioMedicine, 2015 Nov siRNA SR304946
TSC22D3 L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells Cell Death Differ., 2014 Aug siRNA SR301284
TT300001 IL-1ß induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells J. Cell. Biochem., 2014 Aug siRNA SR30004
TWIST1 ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2 Biochem. J., 2016 Apr siRNA SR304977
TXN2 Txn2 haplodeficiency does not affect cochlear antioxidant defenses or accelerate the progression of cochlear cell loss or hearing loss across the lifespan Exp. Gerontol., 2020 Aug siRNA SR403788
TXNIP Low expression of the PPARγ-regulated gene thioredoxin-interacting protein accompanies human melanoma progression and promotes experimental lung metastases Scientific reports, 2021 Apr siRNA SR307241
TXNIP Protein acyltransferase DHHC3 regulates breast tumor growth, oxidative stress and senescence Cancer Res., 2017 Oct siRNA SR307241
TYMS DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide Eur. J. Pharmacol., 2019 Sep siRNA SR304984
UBE2M CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation Genes Dev., 2015 Nov siRNA SR305963
UCK1 Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine Leukemia Dec 2013., 2013 Dec siRNA SR313172
UCK2 Resistance to Azacitidine Is Determined at Cellular Level By Lower Expression of Nucleoside Metabolizing Enzymes Blood, 2016 Dec siRNA SR322152
UCP2 The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses J. Neurochem., 2015 Jul siRNA SR504079
UCP2 Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD(+)/SIRT1 Reduction Cell, 2014 May siRNA SR305019
UGT1A9 Dapagliflozin Inhibits Cell Adhesion to Collagen I and IV and Increases Ectodomain Proteolytic Cleavage of DDR1 by Increasing ADAM10 Activity Molecules, 2020 Jan siRNA SR310169
Ulk1 Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research, 2022 Nov siRNA SR514693
URI1 URI knockdown induces autophagic flux in gastric cancer cells Am J Cancer Res, 2018 Oct siRNA SR322507
URI1 URI prevents potassium dichromate-induced oxidative stress and cell death in gastric cancer cells Am J Transl Res, 2016 Dec siRNA SR305745
URI1 URI expression in cervical cancer cells is associated with higher invasion capacity and resistance to cisplatin Am J Cancer Res, 2015 Jun siRNA SR305745