shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
SMAD4 The transcription factor GLI1 interacts with SMAD proteins to modulate TGFß-induced gene expression in a PCAF-dependent manner J. Biol. Chem. April 2014, 2014 Apr shRNA TG309253
Smad7 microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition Nat Commun, Jan 2014., 2014 Jan shRNA TG320409
SMARCE1 SWI/SNF Regulates the Cellular Response to Hypoxia J. Biol. Chem., Feb 2009; 284: 4123 - 4131, 2009 Feb shRNA TR309242
SMG1 Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival Clin. Cancer Res., Mar 2012; 18: 1257 - 1267., 2012 Mar shRNA TR318864
SMN1 iPSC-derived functional human neuromuscular junctions model the pathophysiology of neuromuscular diseases JCI Insight, 2019 Sep shRNA TR301496
Smo Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS biology, 2022 Sep shRNA TG510788
SMO Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing Nature Neuroscience (29 November 2009), 2009 Nov shRNA TR309234
SMPDL3B Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis Science Translational Medicine, Jun 2011; 3: 85ra46, 2011 Jun shRNA TR309229
Smurf1 Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. Nature communications, 2016 Mar shRNA TL505101
SNAI1 CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells International journal of molecular sciences, 2021 Jan shRNA TR309226
SNAI1 Inflammatory mediators drive metastasis and drug resistance in head and neck squamous cell carcinoma Laryngoscope, 2015 Mar shRNA TG309226
SNAI1 BMK1 Kinase Suppresses Epithelial–Mesenchymal Transition through the Akt/GSK3ß Signaling Pathway Cancer Res., Mar 2012; 72: 1579 - 1587., 2012 Mar shRNA TR309226
SNAI1 Role of {Delta}Np63{gamma} in Epithelial to Mesenchymal Transition J. Biol. Chem., Feb 2011; 286: 3915 - 3924, 2011 Feb shRNA TG309226
SNAI1 Proinflammatory Mediators Upregulate Snail in Head and Neck Squamous Cell Carcinoma Clin. Cancer Res., Oct 2009; 15: 6018 - 6027, 2009 Sep shRNA TR309226
SNAI2 MicroRNA-124 suppresses Slug-mediated lung cancer metastasis Eur Rev Med Pharmacol Sci, 2016 Sep shRNA TR309225
SNAP25 The SNARE Proteins SNAP25 and Synaptobrevin Are Involved in Endocytosis at Hippocampal Synapses J. Neurosci., May 2013; 33: 9169 - 9175., 2013 May shRNA TF711123
SNX27 Actin-Sorting Nexin 27-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling J. Biol. Chem., 2016 Mar shRNA TF301468
SOCS3 Human ß-defensin-2 enhances IFN-{gamma} and IL-10 production and suppresses IL-17 production in T cells J. Leukoc. Biol., Jun 2011; 89: 935 - 944, 2011 Jun shRNA TR316847
SOD2 Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells Toxicol. Appl. Pharmacol., 2016 Sep shRNA TG309190
SOD2 Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells Toxicol. Appl. Pharmacol., 2016 Jul shRNA TR309190
SOD2 Anti-oncogenic and oncogenic properties of Nrf2 in arsenic-induced carcinogenesis J. Biol. Chem., 2015 Sep shRNA TG309190
SOD2 Mitochondrial superoxide dismutase has a pro-tumorigenic role in ovarian clear cell carcinoma Cancer Res., 2015 Sep shRNA TG309190
SOD2 Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development J. Biol. Chem., 2014 Dec shRNA TG309190
Sort1 Sortilin regulates sorting and secretion of Sonic hedgehog J. Cell. Sci., 2016 Sep shRNA TR502101
SORT1 Sortilin regulates progranulin action in castration-resistant prostate cancer cells Endocrinology, 2014 Nov shRNA TG309180
SOX2 Efficient extravasation of tumor-repopulating cells depends on cell deformability Sci Rep, 2016 Jan shRNA TG515613
SOX2 Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming Stem Cell Reports, 2015 Oct shRNA TG515613
SOX2 SOX2 expression in the developing, adult, as well as, diseased prostate Prostate Cancer Prostatic Dis., 2014 Aug shRNA TR309173
Sox2 Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression Nat Commun, 2014 Aug shRNA TG515613
SOX4 SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells Mol. Cancer, 2015 Feb shRNA TF315513
SOX4 Down-regulated SOX4 expression suppresses cell proliferation, metastasis and induces apoptosis in Xuanwei female lung cancer patients J. Cell. Biochem., 2015 Jan shRNA TG315513
SOX4 The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells Development, Feb 2013; 140: 740 - 750., 2013 Feb shRNA TF315513
Sox9 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell reports, 2019 Aug shRNA TF511411
SOX9 Oncogenicity of the Developmental Transcription Factor Sox9 Cancer Res., Mar 2012; 72: 1301 - 1315., 2012 Mar shRNA TR309170
SP1 The Specificity Protein Factor Sp1 Mediates Transcriptional Regulation of P2X7 Receptors in the Nervous System J. Biol. Chem., Dec 2012; 287: 44628 - 44644., 2012 Dec shRNA TF502115
Sp7 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell reports, 2019 Aug shRNA TF514041
SP7 Antagonistic interactions between osterix and pyrophosphate during cementum formation Bone, 2019 May shRNA TG514041
SPAG11A Transgenesis and active immunization mediated reduction of sperm associated antigen 11A mRNA and protein levels affect fecundity in the rat Theriogenology, 2020 Aug shRNA TG713093
SPARCL1 Methylation of SPARCL1 Is Associated with Oncologic Outcome of Advanced Upper Urinary Tract Urothelial Carcinoma Int J Mol Sci, 2019 Apr shRNA TG309157
SPC24 SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling Oncotarget, 2017 Dec shRNA TG301421
SPC24 SPC24 is critical for anaplastic thyroid cancer progression Oncotarget, 2017 Mar shRNA TR301421
Sphk1 Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis Carcinogenesis, 2018 Dec shRNA TF512690
SPHK1 Comprehensive gene and microRNA expression profiling reveals a role for miRNAs in the oncogenic roles of SphK1 in papillary thyroid cancer J. Cancer Res. Clin. Oncol, 2016 Dec shRNA TR301413
Sphk1 Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway Journal of immunology (Baltimore, Md. : 1950), 2013 Oct shRNA TL512690
Sphk1 Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway Journal of immunology (Baltimore, Md. : 1950), 2013 Oct shRNA TF512690
Sphk1 Inducible IL-33 Expression by Mast Cells Is Regulated by a Calcium-Dependent Pathway J. Immunol., Oct 2012; 189: 3421 - 3429., 2012 Oct shRNA TG301413
Sphk2 Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway Journal of immunology (Baltimore, Md. : 1950), 2013 Oct shRNA TL701575
Sphk2 Inducible IL-33 Expression by Mast Cells Is Regulated by a Calcium-Dependent Pathway J. Immunol., Oct 2012; 189: 3421 - 3429., 2012 Oct shRNA TG301412
Sphkap Neuronal ER-plasma membrane junctions couple excitation to Ca 2+ -activated PKA signaling Nature Communications, 2023 Aug shRNA TL708390
Spi1 Alzheimer\'s-associated PU.1 expression levels regulate microglial inflammatory response Neurobiology of disease, 2020 Dec shRNA TG502008