shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Spi1 A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease Nat. Neurosci., 2017 Aug shRNA TG502008
SPI1 A common haplotype lowers SPI1 (PU. 1) expression in myeloid cells and delays age at onset for Alzheimer's disease bioRxiv, 2017 Feb shRNA TG502008
SPI1 Repression of primitive erythroid program is critical for the initiation of multi-lineage hematopoiesis in mouse development J. Cell. Physiol., 2016 May shRNA TG502008
SPP1 Identification of a Biphasic Role for Genistein in the Regulation of Prostate Cancer Growth and Metastasis Cancer Res., Apr 2009; 69: 3695 - 3703., 2009 Apr shRNA TR309135
SPRY2 Regulation of vascular signalling by nuclear Sprouty2 in fetal lung epithelial cells: Implications for co-ordinated airway and vascular branching in lung development Comp. Biochem. Physiol. B, Biochem. Mol. Biol., 2018 Feb shRNA TR309130
SPRY2 Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3 Leukemia, 2017 Apr shRNA TG515588
Spry4 Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis PLoS ONE. 2009; 4(5): e5467, 2009 May shRNA TR509780
SPTAN1 α-Fodrin is required for the organization of functional microtubules during mitosis Cell Cycle, 2019 Aug shRNA TR309127
SPTBN1 Transcriptional Regulation of STAT3 by SPTBN1 and SMAD3 in HCC Through cAMP-Response Element-Binding Proteins ATF3 and CREB2* Carcinogenesis, 2014 Aug shRNA TR301396
SQSTM1 Enhanced Sensitivity to NVP-BEZ235 by Inhibition of p62/SQSTM1 in Human Bladder Cancer KoTCC-1 Cells Both In Vitro and In Vivo In Vivo, 2020 Dec shRNA TR309121
SQSTM1 Roles of ROS, Nrf2, and autophagy in cadmium-carcinogenesis and its prevention by sulforaphane Toxicol. Appl. Pharmacol., 2018 Jun shRNA TG309121
SQSTM1 Anti-oncogenic and oncogenic properties of Nrf2 in arsenic-induced carcinogenesis J. Biol. Chem., 2015 Sep shRNA TG309121
SR30004 Liver Molecular Mechanisms Involved in Type 2 Diabetes: An Investigation Using Roux-en Y Gastric Bypass as a Human Model of Diabetes Remission Thesis July 2014, 2014 Jul shRNA TR30015
SRC Lusianthridin Targeting of Lung Cancer Stem Cells via Src-STAT3 Suppression Phytomedicine, 2019 Apr shRNA TR320529
SRC Fc?-receptor IIa-mediated Src Signaling Pathway is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection PLoS Pathog, 2016 Dec shRNA TR320529
SRC alpha3/4 Fucosyltransferase 3-Dependent Synthesis of Sialyl Lewis A on CD44 Variant Containing Exon 6 Mediates Polymorphonuclear Leukocyte Detachment from Intestinal Epithelium during Transepithelial Migration J Immunol. 2013 Nov 1;191(9):4804-17, 2013 Nov shRNA TG320529
SRC TR3 Modulates Platinum Resistance in Ovarian Cancer Cancer Res., Aug 2013; 73: 4758 - 4769., 2013 Aug shRNA TG320529
SREBF1 Myostatin induces insulin resistance via Cblb-mediated degradation of IRS1 in response to high calorie diet intake J. Biol. Chem., Jan 2014., 2014 Jan shRNA TG514167
SREBF1 Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells Mol. Cancer Res., Jan 2012; 10: 133 - 142., 2012 Jan shRNA TR309117
SREBF1 Androgen Receptor Survival Signaling Is Blocked by Anti-ß2-microglobulin Monoclonal Antibody via a MAPK/Lipogenic Pathway in Human Prostate Cancer Cells J. Biol. Chem., Mar 2010; 285: 7947 - 7956, 2010 Mar shRNA TR309117
Srebf2 Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity Genes & Development, 2017 Jul shRNA TG510683
SRRT ARS2 is required for retinal progenitor cell S-phase progression and Müller glial cell fate specification Biochem. Cell Biol., 2019 Jan shRNA TG514443
SRRT Mutagenesis of ARS2 Domains to Assess Possible Roles in Cell Cycle Progression, MicroRNA and Replication-dependent Histone mRNA Biogenesis Mol. Cell. Biol., 2015 Aug shRNA TG514443
SRSF1 Regulation of the Alternative Splicing and Function of Cyclin T1 by the Serine-arginine-rich Protein ASF/SF2 J. Cell. Biochem., 2017 Apr shRNA TR309496
SRSF5 SRSF5 Regulates the Expression of BQ323636.1 to Modulate Tamoxifen Resistance in ER-Positive Breast Cancer. Cancers, 2023 Apr shRNA TL309487
St6galnac4 Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche Cancer Discov, 2014 Nov shRNA TG502032
STARD4 Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis Biochim Biophys Acta Mol Cell Biol Lipids, 2020 Apr shRNA TG301353
STARD4 STARD4 abundance regulates sterol transport and sensing Mol. Biol. Cell, Nov 2011; 22: 4004 - 4015., 2011 Nov shRNA TR506047
STAT1 STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2 Oncol. Rep., 2018 Nov shRNA TG301349
STAT1 Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas J. Clin. Invest, 2017 Mar shRNA TG502153
STAT1 STAT1 drives tumor progression in serous papillary endometrial cancer Cancer Res., 2014 Sep shRNA TG301349
STAT1 A switch from hBrm to Brg1 at IFN?-activated sequences mediates the activation of human genes Cell Research 20, 1345-1360 (16 November 2010) doi:10.1038/cr.2010.155 Original Article, 2010 Nov shRNA
STAT1 Stat1 mediates an auto-regulation of hsp90beta gene in heat shock response. Cellular signalling, 2010 Jun shRNA TR301349
Stat3 Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis Molecular Oncology, 2022 Jun shRNA TF502154
STAT3 ß-cell mass restoration by α7-nicotinic acetylcholine receptor activation J. Biol. Chem., 2018 Nov shRNA TG709368
STAT3 GLI3 knockdown decreases stemness, cell proliferation and invasion in oral squamous cell carcinoma Int. J. Oncol., 2018 Sep shRNA TG301348
STAT3 Regulation of endometrial cell proliferation by estrogen-induced BDNF signaling pathway Gynecol. Endocrinol, 2017 Mar shRNA TR301348
STAT3 Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism Sci Rep, 2016 Nov shRNA TR301348
STAT3 Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB Oncotarget, 2016 Oct shRNA TR301348
STAT3 Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling Oncotarget, 2016 Aug shRNA TR301348
STAT3 Feed forward reciprocal activation of PAFR and STAT3 regulates epithelial-mesenchymal transition in non-small cell lung cancer Cancer Res., 2015 Sep shRNA TR301348
STAT3 Autophagy inhibition by sustained over-production of IL-6 contributes to arsenic-induced carcinogenesis Cancer Res., 2014 May shRNA TF301348
Stim1 Activity-dependent endoplasmic reticulum Ca 2+ uptake depends on Kv2.1-mediated endoplasmic reticulum/plasma membrane junctions to promote synaptic transmission Proceedings of the National Academy of Sciences of the United States of America, 2022 Jul shRNA TR707032
STIM1 Role of STIM2 and Orai proteins in regulating TRPC1 channel activity upon calcium store depletion Cell calcium, 2021 Jun shRNA TG309049
STIM1 Axonal Endoplasmic Reticulum Ca(2+) Content Controls Release Probability in CNS Nerve Terminals Neuron, 2017 Feb shRNA TR707032
STIM1 Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation Immunity, Inflammation and Disease, 2015 May shRNA TF502160
STIM1 STIM1 and STIM2 Proteins Differently Regulate Endogenous Store-operated Channels in HEK293 Cells J. Biol. Chem., 2014 Dec shRNA TR309049
STIM1 JBC Papers in Press. Published on December 22, 2014 as Manuscript M114. 601856 The Journal of Biological Chemistry, 2014 Dec shRNA TR309049
STIM1 Amplified lipid rafts of malignant cells constitute a target for inhibition of aberrantly active NFAT and melanoma tumor growth by the aminobisphosphonate zoledronic acid Carcinogenesis, 2014 Aug shRNA TG309049
STIM1 Molecular mechanisms of spontaneous and directed mast cell motility J. Leukoc. Biol., Nov 2012; 92: 1029 - 1041., 2012 Nov shRNA TG309049