shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
STIM1 Lipid rafts couple store-operated Ca2+ entry to constitutive activation of PKB/Akt in a Ca2+/calmodulin-, Src- and PP2A-mediated pathway and promote melanoma tumor growth Carcinogenesis, Feb 2012; 10.1093/carcin/bgs021., 2012 Feb shRNA TR309049
Stim1 Mitochondria depletion abolishes agonist-induced Ca2+ plateau in airway smooth muscle cells - potential role of H2O2 Am J Physiol Lung Cell Mol Physiol, Nov 2009; 10.1152/ajplung.00134.2009, 2009 Nov shRNA TR707032
STIM1 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR309049
STIM1 Store-operated cyclic AMP signalling mediated by STIM1 Nature Cell Biology 11, 433-442 (15 March 2009), 2009 Mar shRNA TR309049
STIM1 Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line J. Immunol., Feb 2008; 180: 2233 - 2239., 2008 Feb shRNA TR309049
STIP1 Stress-induced phosphoprotein 1 promotes pancreatic cancer progression through activation of the FAK/AKT/MMP signaling axis. Pathology, research and practice, 2020 Mar shRNA TL309048
STK11 Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability Transl Psychiatry. 2013 Oct 22;3:e317, 2013 Oct shRNA TG706613
STMN2 The landscape of multiscale transcriptomic networks and key regulators in Parkinson\'s disease Nat Commun, 2019 Nov shRNA TF511127
STRIP2 STRIP2 is indispensable for the onset of embryonic stem cell differentiation olecular Therapy: Methods & Clinical Developmen, 2017 Apr shRNA TR508344
Strip2 Fam40b is required for lineage commitment of murine embryonic stem cells Cell Death Dis July 2014, 2014 Jul shRNA TR508344
STUB1 Hsp90 inhibition renders iNOS aggregation and the clearance of iNOS aggregates by proteasomes requires SPSB2 Free Radic. Biol. Med., 2018 Jan shRNA TG316909
STUB1 A Critical Role for CHIP in the Aggresome Pathway Mol. Cell. Biol., Jan 2009; 29: 116 - 128., 2009 Jan shRNA TR316909
SUMO1 Adenosine Signaling Mediates SUMO-1 Modification of IB during Hypoxia and Reoxygenation J. Biol. Chem., May 2009; 284: 13686 - 13695., 2009 May shRNA TR316774
SUN1 Fluorescence Fluctuation Spectroscopy Reveals Differential SUN Protein Oligomerization In Living Cells Mol. Biol. Cell, 2018 Mar shRNA TF300647
SUN2 Fluorescence Fluctuation Spectroscopy Reveals Differential SUN Protein Oligomerization In Living Cells Mol. Biol. Cell, 2018 Mar shRNA TF300646
SUOX Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells Oncotarget, 2015 Oct shRNA TG309008
SUPT5H A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Oct 2012; 209: 2099 - 2111., 2012 Oct shRNA TG309005
SUPT5H A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Sep 2012; 10.1084/jem.20112145., 2012 Sep shRNA TR309005
Sv2c Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinsons disease bioRxiv, 2016 Sep shRNA TR711401
Svbp Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science (New York, N.Y.), 2018 Jan shRNA TL517601
SYK Fc?-receptor IIa-mediated Src Signaling Pathway is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection PLoS Pathog, 2016 Dec shRNA TR320543
SYK The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aß Production and Tau Hyperphosphorylation J. Biol. Chem., 2014 Oct shRNA TG320543
Syngr3 Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau. Neuron, 2019 Jul shRNA TL502195
SYNGR3 Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau Neuron, 2018 Feb shRNA TF705557
TACSTD2 Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways BMC Cancer, 2017 Jul shRNA TR308966
TAGLN2 Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas Oncotarget, 2018 Dec shRNA TG316819
TAP1 Cellular and Molecular Requirements for the Selection of In Vitro–Generated CD8 T Cells Reveal a Role for Notch J. Immunol., Aug 2013; 191: 1704 - 1715., 2013 Aug shRNA TG308949
TAS2R14 Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin International Journal of Oncology, 2023 Jan shRNA TL301238
TAS2R14 Activation of airway epithelial bitter taste receptors by Pseudomonas aeruginosa quinolones modulates calcium, cyclic-AMP, and nitric oxide signaling J. Biol. Chem., 2018 May shRNA TR301238
TBC1D23 Homozygous Truncating Variants in TBC1D23 Cause Pontocerebellar Hypoplasia and Alter Cortical Development Am. J. Hum. Genet., 2017 Aug shRNA TR503947
TBC1D9 Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell-derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity Mol Ther Nucleic Acids. 2013 Oct 1;2:e126, 2013 Oct shRNA TF308932
Tcf3 Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. Molecular cell, 2022 Nov shRNA TL510854
TCF3 Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. Molecular cell, 2022 Nov shRNA TL308904
Tcf4 ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis Genes & Development, 2015 Jan shRNA TG502233
TDG Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes. International journal of oncology, 2011 Sep shRNA TG316755
TDP1 Expression Of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies J. Biol. Chem., Jan 2009; 10.1074/jbc.M809462200., 2009 Jan shRNA TR308891
TEAD2 Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. Molecular cell, 2022 Nov shRNA TL308887
Tead2 Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis. Molecular cell, 2022 Nov shRNA TR502250
TERF2 DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair Mol. Cell. Biol., Jul 2009; 29: 3597 - 3604, 2009 Jul shRNA TR308880
TESK1 Tesk1 Interacts with Spry2 to Abrogate Its Inhibition of ERK Phosphorylation Downstream of Receptor Tyrosine Kinase Signaling J. Biol. Chem., Jan 2008; 283: 1679 - 1691., 2008 Jan shRNA TR308879
TET2 TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H2S System Front Pharmacol, 2017 Aug shRNA TG303734
Tet2 Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro Sci Rep, 2017 Mar shRNA TR513547
TFAM Knockdown of TFAM in Tumor Cells Retarded Autophagic Flux through Regulating p53 Acetylation and PISD Expression Cancers (Basel) 2020, 2020 Feb shRNA TG316756
TFAM Down-regulation of TFAM increases the sensitivity of tumour cells to radiation via p53/TIGAR signalling pathway J. Cell. Mol. Med., 2019 May shRNA TG502265
TFAM Cyclooxygenase-2-Mediated Up-Regulation of Mitochondrial Transcription Factor A Mitigates the Radio-Sensitivity of Cancer Cells Int J Mol Sci, 2019 Mar shRNA TG502265
TFAM HuR stabilizes TFAM mRNA in an ATM/p38-dependent manner in ionizing irradiated cancer cells Cancer Sci., 2018 Aug shRNA TR316756
TFAM Mitochondrial transcription factor A regulated ionizing radiation-induced mitochondrial biogenesis in human lung adenocarcinoma A549 cells J Radiat Res, May 2013; 10.1093/jrr/rrt046., 2013 May shRNA TR316756
TFEB Mitochondrial Translocation of TFEB Regulates Complex I and Inflammation SSRN Electronic Journal, 2021 Mar shRNA TF308867
TFEB Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation Int J Mol Sci, 2019 Mar shRNA TR308867
TFEB Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB PLOS ONE, Feb 2014., 2014 Feb shRNA TR308867