shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
TGFB1 Mesenchymal stem cells enhance tumorigenic properties of human glioblastoma through independent cell-cell communication mechanisms Oncotarget, 2018 May shRNA TG308855
TGFB1 TGF Beta1 Expression Correlates with Survival and Tumor Aggressiveness of Prostate Cancer Ann. Surg. Oncol., 2015 Aug shRNA TG308855
TGFB1 TGF-ß1 mediates the radiation response of prostate cancer J. Mol. Med., 2014 Sep shRNA TG308855
TGFB1 Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production Arthritis & Rheumatism Volume 60 Issue 5, Pages 1438 - 1450, 2009 Apr shRNA TR308855
TGFBR1 Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells J. Biol. Chem., 2018 Jun shRNA TR709395
TGFBR1 The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes Cell. Mol. Biol. Lett., 2014 Dec shRNA TG709395
TGFBR2 Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells J. Biol. Chem., 2018 Jun shRNA TR711255
Tgfbr2 TGF-ß Signaling Regulates Cementum Formation through Osterix Expression Sci Rep, 2016 May shRNA TR516186
Tgfbr2 Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer Genome Biology, 2014 Aug shRNA TG516186
tGFP The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer Nucleic Acids Res., 2015 Dec shRNA TR30016
THOC2 THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme American Journal of Cancer Research, 2023 Jun shRNA TL301111
Thrap3 Thrap3 promotes R-loop resolution via interaction with methylated DDX5 Experimental & Molecular Medicine, 2021 Oct shRNA TL701343
TIAM1 Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis Cell Rep, 2014 Nov shRNA TG511327
TIMP1 Regulation of soluble vascular endothelial growth factor receptor 1 secretion from human endothelial cells by tissue inhibitor of metalloproteinase 1 Molecular Human Reproduction, doi:10.1093/molehr/gap053, 2009 Jul shRNA TR308814
TIMP3 Mesenchymal Stem Cells Regulate Blood-Brain Barrier Integrity Through TIMP3 Release After Traumatic Brain Injury Science Translational Medicine, Nov 2012; 4: 161ra150., 2012 Nov shRNA TR308813
Tissue Imaging of motor-dependent transport in neuronal and nonneuronal cells at high spatial and temporal resolution Methods in Cell Biology, 2015 Jun shRNA TR30007
Tle1 Transducin-like Enhancer of Split-1 (TLE1) Combines with Forkhead Box Protein G1 (FoxG1) to Promote Neuronal Survival J. Biol. Chem., Apr 2012; 287: 14749 - 14759., 2012 Apr shRNA TG511107
TLE5 Repression of HNF1a-mediated transcription by amino-terminal enhancer of split (AES) Biochem. Biophys. Res. Commun., 2015 Dec shRNA TR306804
TLE5 Amino-terminal Enhancer of Split (AES) Interacts with the Oncoprotein NUP98-HOXA9 and Enhances Its Transforming Ability J. Biol. Chem., Nov 2011; 286: 38989 - 39001., 2011 Nov shRNA TR306804
TLK1 The TLK1–MK5 Axis Regulates Motility, Invasion, and Metastasis of Prostate Cancer Cells Cancers, 2022 Nov shRNA TL320623
TLK1 DNA damage response and repair data with pharmacological modulators of Tousled Data in Brief, 2016 Mar shRNA TG320623
TLR2 Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis MBio, 2016 Jun shRNA TR320553
TLR4 Atractylenolide-I Suppresses Tumorigenesis of Breast Cancer by Inhibiting Toll-Like Receptor 4-Mediated Nuclear Factor-κB Signaling Pathway Frontiers in pharmacology, 2020 Dec shRNA TG320555
TLR4 Atractylenolide-I suppresses tumorigenesis of breast cancer by inhibiting toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway Research Square, 2020 Aug shRNA TG320555
TLR4 Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production Gut Microbes, 2020 Jul shRNA TG320555
TLR4 Cathelicidin senses enteric pathogen Salmonella typhimurium/LPS for colonic chemokine generation: a new innate immune role for a host defense peptide bioRxiv, 2018 Aug shRNA TG320555
TLR4 Resveratrol alleviates lysophosphatidylcholine-induced damage and inflammation in vascular endothelial cells Mol Med Rep, 2017 Dec shRNA TG320555
TLR4 HSV-2 Increases TLR4-Dependent Phosphorylated IRFs and IFN-ß Induction in Cervical Epithelial Cells PLoS ONE e94806 9 4. April 2014, 2014 Apr shRNA TG320555
TLR4 TLR4-MyD88/Mal-NF-kB Axis Is Involved in Infection of HSV-2 in Human Cervical Epithelial Cells PLoS ONE e80327, 2013 Nov shRNA TG320555
TLR5 Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis MBio, 2016 Jun shRNA TR308792
TLR7 Toll-Like Receptor 7 Mediates Inflammation Resolution and Inhibition of Angiogenesis in Non-Small Cell Lung Cancer Cancers, 2021 Feb shRNA TG301078
TLR9 Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis MBio, 2016 Jun shRNA TR301076
TM4SF5 Interaction of tetraspan(in) TM4SF5 with CD44 promotes self-renewal and circulating capacities of hepatocarcinoma cells Hepatology, 2015 Jan shRNA TG308787
TMEM106A Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis J. Cell. Mol. Med., 2014 Jun shRNA TF301042
Tmem106b Lysosome size, motility and stress response regulated by Fronto-Temporal Dementia modifier TMEM106B Molecular and cellular neurosciences, 2014 Jul shRNA TL504639
Tmem126a Novel transmembrane protein 126A (TMEM126A) Couples with CD137L Reverse Signals in Myeloid cells Cellular signalling, 2013 Dec shRNA TL503575
TMEM127 Germline mutations in TMEM127 confer susceptibility to pheochromocytoma Nature Genetics 42, 229-233 (14 February 2010) doi:10.1038/ng.533 Letter, 2010 Feb shRNA TR301024
Tmem184a Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1 The Journal of Biological Chemistry, 2016 Mar shRNA TL702927
Tmem184a Transmembrane Protein 184A Is a Receptor Required for Vascular Smooth Muscle Cell Responses to Heparin The Journal of Biological Chemistry, 2016 Mar shRNA TL702927
TMEM184A Heparin decreases in TNFa;-induced endothelial stress responses require transmembrane protein 184A and induction of dual specificity phosphatase-1 J. Biol. Chem., 2016 Jan shRNA TG702927
TMEM88 Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer Gynecol. Oncol., 2016 Sep shRNA TR318781
Tmod2 Down-regulated in renal cell carcinoma 1 (DRR1) regulates axon outgrowth during hippocampal neuron development. Biochemical and biophysical research communications, 2021 Aug shRNA TL711420
TMOD2 Down-regulated in renal cell carcinoma 1 (DRR1) regulates axon outgrowth during hippocampal neuron development Biochemical and biophysical research communications, 2021 Apr shRNA TG711420
TNF Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation Cytokine, 2019 Jan shRNA TR318768
TNF Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells Oncogene, 2018 Mar shRNA TG318768
TNF Targeting Transmembrane TNF-a Suppresses Breast Cancer Growth Cancer Res., Jul 2013; 73: 4061 - 4074., 2013 Jul shRNA TG318768
Tnfaip2 Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy Autophagy, 2022 Jun shRNA TL513846
TNFAIP3 Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR320557
TNFAIP6 Acute and Temporal Expression of TNF-a-stimulated Gene 6 Product,TSG-6,in Mesenchymal Stem Cells Creates Microenvironments Required for Their Successul Transplantation into the Muscle Tissue J. Biol. Chem., 2015 Jul shRNA TF517014
TNFRSF10C Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR308740