shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
TNFRSF10D Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR308739
TNFRSF11B Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR308738
TNFRSF1B WISP1, a Pro-mitogenic, Pro-survival Factor, Mediates Tumor Necrosis Factor- (TNF-)-stimulated Cardiac Fibroblast Proliferation but Inhibits TNF--induced Cardiomyocyte Death J. Biol. Chem., May 2009; 284: 14414 - 14427, 2009 May shRNA TR308733
TNFSF10 Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR308728
TNFSF10 CCN1 sensitizes esophageal cancer cells to TRAIL-mediated apoptosis Exp. Cell Res., 2017 Oct shRNA TR308728
TNIK Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK J. Pharmacol. Exp. Ther., 2015 Dec shRNA TF320665
TNK2 ACK1 promotes hepatocellular carcinoma progression via downregulating WWOX and activating AKT signaling Int. J. Oncol., 2015 May shRNA TR320634
TNKS1BP1 Endothelial p130cas confers resistance to anti-angiogenesis therapy Cell reports, 2022 Feb shRNA TL300907
TNMD Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children's Cohort and Implications of the Gene in Adipocyte Metabolism Sci Rep, 2019 Mar shRNA TR300905
TNPO3 Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection Biosci. Biotechnol. Biochem., 2015 Feb shRNA TG315644
TOP2B(GFP vector) Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements Nature Genetics (4 July 2010) doi:10.1038/ng.613 Article, 2010 Jul shRNA
TOPBP1 ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress Cell July 2014, 2014 Jul shRNA TR308695
TOX MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation Sci Adv, 2019 Dec shRNA TG507539
TOX3 TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex J. Cell Sci., Jan 2011; 124: 252 - 260, 2011 Jan shRNA TR300899
TP53 COUP-TFII Overexpression Inhibits Cell Proliferation and Invasion via Increased Expression of p53 and PTEN and Decreased Akt Phosphorylation in Human Colorectal Cancer SNU-C4 Cells Anticancer Res., 2020 Feb shRNA TG320558
TP53 TRIM8 Blunts the Pro-proliferative Action of ΔNp63α in a p53 Wild-Type Background Front Oncol, 2019 Nov shRNA TR320558
TP53 p53-Dependent and -Independent Responses of Cells Challenged by Photosensitization Photochem. Photobiol., 2018 Sep shRNA TG320558
TP53 p53 is essential for embelin-induced apoptosis in p53-wildtype prostate cancer cells Int J Clin Exp Med, 2016 Oct shRNA TR320558
TP53 Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways PLoS ONE, 2015 Aug shRNA TG320558
TP53 Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma Neoplasia, 2014 Dec shRNA TR320558
TP53 Oncomorphic TP53 Mutations in Gynecologic Cancers Lose the Normal Protein: Protein Interactions with the microRNA Microprocessing Complex Journal of Cancer Therapy April 2014, 2014 Apr shRNA TR320558
TP53 Oncomorphic Tp53 mutations in advanced serous ovarian carcinomas Thesis, 2014 Jan shRNA TF320558
TP53 Gene Expression Profiles Resulting from Stable Loss of p53 Mirrors Its Role in Tissue Differentiation PLOS ONE e82494, 2013 Nov shRNA TG320558
TP53 Deacetylation of p53 induces autophagy by suppressing Bmf expression J. Cell Biol., Apr 2013; 201: 427 - 437., 2013 Apr shRNA TG320558
TP53 Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival Clin. Cancer Res., Mar 2012; 18: 1257 - 1267., 2012 Mar shRNA TR320558
TP53BP1 Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients Oncogene, 2015 Dec shRNA TR308691
TP53BP1 MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection Nature, 2015 Mar shRNA TF308691
TP53BP1 MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection Nature, 2015 Mar shRNA TR308691
TP63 TGFß3 Regulates Periderm Removal through ?Np63 in the Developing Palate J. Cell. Physiol., 2014 Oct shRNA TR308688
TP63 OCT4 as a target of miR-34a stimulates p63 but inhibits p53 to promote human cell transformation Cell Death Dis, Jan 2014., 2014 Jan shRNA TG308688
TP73 The p53 family member p73 modulates the pro-proliferative role of IGFBP3 in short children born SGA Mol. Biol. Cell, 2015 Jun shRNA TR308689
Tpcn2 VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling Proc. Natl. Acad. Sci. U.S.A., 2014 Oct shRNA TR300883
TPK1 TPK1 as a predictive marker for the anti-tumour effects of simvastatin in gastric cancer Pathol. Res. Pract., 2020 Jan shRNA TG300880
Tpp2 A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport Cell reports, 2019 Nov shRNA TL711260
TPR Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways PLoS ONE, 2015 Aug shRNA TG308677
TR20003 Circadian Modulation of 8-Oxoguanine DNA Damage Repair Sci Rep, 2015 Sep shRNA TR20003
TR20003 Feed forward reciprocal activation of PAFR and STAT3 regulates epithelial-mesenchymal transition in non-small cell lung cancer Cancer Res., 2015 Sep shRNA TR20003
TR20003 Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region J. Virol., 2015 Aug shRNA TR20003
TR20003 SLC9A3R1 stimulates autophagy via BECN1 stabilization in breast cancer cells Autophagy, 2015 Jul shRNA TR20003
TR20003 STX13 regulates cargo delivery from recycling endosomes during melanosome biogenesis J. Cell. Sci., 2015 Jul shRNA TR20003
TR20003 TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-?B-induced increase in cFLIP Cytokine, 2015 Jul shRNA TR20003
TR20003 Different states of integrin LFA-1 aggregation are controlled through its association with tetraspanin CD9 Biochim. Biophys. Acta, 2015 May shRNA TR20003
TR20003 Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells Br. J. Cancer, 2015 May shRNA TR20003
TR20003 Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents PLoS ONE, 2015 May shRNA TR20003
TR20003 Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma Int. J. Oncol., 2014 Dec shRNA TR20003
TR20003 STING agonists induce an innate antiviral immune response against hepatitis B virus Antimicrob. Agents Chemother., 2014 Dec shRNA TR20003
TR30002 Aberrant glycosylation promotes lung cancer metastasis through adhesion to galectins in the metastatic niche Cancer Discov, 2014 Nov shRNA TR30002
TR30003 A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy Cell Death Dis, 2015 Oct shRNA TR30003
TR30003 TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-?B-induced increase in cFLIP Cytokine, 2015 Jul shRNA TR30003
TR30007 Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus J. Clin. Invest., 2016 Feb shRNA TR30007