shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
TRIM8 TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours Mol. Cancer, 2017 Mar shRNA TR300821
TRIM8 TRIM8 anti-proliferative action against chemo-resistant renal cell carcinoma Oncotarget, 2014 Jun shRNA TR300821
TRIP10 Collective membrane dynamics emerging from curvature-dependent spatial coupling bioRxiv, 2017 Jul shRNA TG712260
Trp53 Maternal Obesity Programs Senescence Signaling and Glucose Metabolism in Osteo-Progenitors From Rat and Human. Endocrinology, 2017 May shRNA TG500002
TRPC1 Molecular mechanisms of spontaneous and directed mast cell motility J. Leukoc. Biol., Nov 2012; 92: 1029 - 1041., 2012 Nov shRNA TG308629
TRPC1 Ca2+ Waves Initiate Antigen-Stimulated Ca2+ Responses in Mast Cells J. Immunol., Nov 2009; 183: 6478 - 6488, 2009 Nov shRNA TR308629
TRPC1 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR308629
TRPC3 ACTIVITY-DEPENDENT RELEASE OF ENDOGENOUS BDNF FROM MOSSY FIBERS EVOKES A TRPC3 CURRENT AND Ca2+ ELEVATIONS IN CA3 PYRAMIDAL NEURONS J Neurophysiol, May 2010; 103: 2846 - 2856, 2010 May shRNA TR308628
TRPC3 Ca2+ Waves Initiate Antigen-Stimulated Ca2+ Responses in Mast Cells J. Immunol., Nov 2009; 183: 6478 - 6488, 2009 Nov shRNA TR308628
TRPC4 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR300814
Trpc5 Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca(2+) influx J. Neurochem., 2015 Nov shRNA TR509727
TRPC5 Cross-Linking of GM1 Ganglioside by Galectin-1 Mediates Regulatory T Cell Activity Involving TRPC5 Channel Activation: Possible Role in Suppressing Experimental Autoimmune Encephalomyelitis J. Immunol., Apr 2009; 182: 4036 - 4045., 2009 Apr shRNA TR308627
TRPC6 TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure Cancers (Basel) 2018, 2018 Sep shRNA TR308626
TRPC6 Hyperforin/HP-β-Cyclodextrin Enhances Mechanosensitive Ca(2+) Signaling in HaCaT Keratinocytes and in Atopic Skin Ex Vivo Which Accelerates Wound Healing Biomed Res Int, 2017 Feb shRNA TF308626
TRPC6 Mechanosensitive ATP release from hemichannels and Ca2+ influx through TRPC6 accelerate wound closure in keratinocytes J. Cell. Sci., 2014 Aug shRNA TF308626
Trpc6 HYPERFORIN MODULATES DENDRITIC SPINE MORPHOLOGY IN HIPPOCAMPAL PYRAMIDAL NEURONS BY ACTIVATING Ca 2+ -PERMEABLE TRPC6 CHANNELS Hippocampus, 2014 Jan shRNA TG711962
TRPC6 Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration FASEB J, Apr 2009; 10.1096/fj.09-131128., 2009 Apr shRNA TR308626
TRPM2 TRPM2 contributes to LPC-induced intracellular Ca(2+) influx and microglial activation Biochem. Biophys. Res. Commun, 2017 Feb shRNA TR515108
TRPM2 The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting Leukemia July 2014, 2014 Jul shRNA TG308624
TRPM4 TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility PLoS ONE, 2015 Jun shRNA TF504191
TRPM7 Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function Mol. Neurobiol., 2019 Aug shRNA TR320704
TRPM7 Cholesterol-induced activation of TRPM7 regulate cell proliferation, migration, and viability of human prostate cells Biochim. Biophys. Acta. April 2014, 2014 Apr shRNA TR320704
TRPM7 Increase in Serum Ca2+/Mg2+ Ratio Promotes Proliferation of Prostate Cancer Cells by Activating TRPM7 Channels J. Biol. Chem., Jan 2013; 288: 255 - 263., 2013 Jan shRNA TG516988
TSC22D1 Transforming Growth Factor-ß–Stimulated Clone-22 Is an Androgen-Regulated Gene That Enhances Apoptosis in Prostate Cancer following Insulin-Like Growth Factor-I Receptor Inhibition Clin. Cancer Res., Dec 2009; 15: 7634 - 7641, 2009 Dec shRNA TR300799
TSPAN8 Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells Oncotarget, 2017 Mar shRNA TR308597
TSPAN8 Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts Oncotarget, 2017 Mar shRNA TR308597
TT200002 AICAR induces Nrf2 activation by an AMPK-independent mechanism in hepatocarcinoma cells Biochem. Pharmacol. July 2014, 2014 Jul shRNA TR30012
TTK Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores J. Cell Biol., Jun 2008; 181: 893 - 901, 2008 Jun shRNA TR320563
TTLL6 Amyloid-Beta oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin EMBO J. 2013 Nov 13;32(22):2920-37., 2013 Sep shRNA TG300748
TUBB3 ßIII-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non–Small Cell Lung Cancer Cancer Res., Jun 2010; 70: 4995 - 5003, 2010 Jun shRNA TR308568
TULP1 Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy Int J Physiol Pathophysiol Pharmacol, 2017 Dec shRNA TR308561
TWIST1 Overcoming acquired resistance of gefitinib in lung cancer cells without T790M by AZD9291 or Twist1 knockdown in vitro and in vivo Arch. Toxicol., 2019 Apr shRNA TF308556
TWIST1 A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells Breast Cancer Res. Treat, 2017 Mar shRNA TF308556
Txndc5 Endoplasmic Reticulum Protein ERp46 in Renal Cell Carcinoma PLoS ONE, 2014 Mar shRNA TG505718
Txnip Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury FJan000Research, Jan 2014., 2014 Jan shRNA TG503152
TXNRD1 Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells Free Radic. Biol. Med., 2016 Sep shRNA TR300712
Ube2e1 Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1 eLife, 2022 Feb shRNA TR502364
UBE2I Modulation of host cell SUMOylation facilitates efficient development of Plasmodium berghei and Toxoplasma gondii Cell. Microbiol, 2017 Jan shRNA TG300697
UBE3A Interaction of HPV E6 oncoproteins with specific proteasomal subunits Virology. 2013 Nov;446(1-2):389-96. doi: 10.1016, 2013 Sep shRNA TG308522
Ube3a Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome PLoS Biology, 2013 Feb shRNA TL502369
UBE4B Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription PLoS Biol., 2015 Apr shRNA TF308519
UBE4B Mitochondrial damage and cholesterol storage in human hepatocellular carcinoma cells with silencing of UBIAD1 gene expression Molecular Genetics and Metabolism Reports, 2014 Sep shRNA TF308519
UBIAD1 Mitochondrial damage and cholesterol storage in human hepatocellular carcinoma cells with silencing of UBIAD1 gene expression Molecular Genetics and Metabolism Reports, 2014 Sep shRNA TF308518
UBR1 Phosphorylation Impacts N-End Rule Degradation of the Proteolytically Activated Form of BMX Kinase JBC, 2017 Sep shRNA TG300681
UBR2 Phosphorylation Impacts N-End Rule Degradation of the Proteolytically Activated Form of BMX Kinase JBC, 2017 Sep shRNA TF300680
UBXN4 Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets Mol. Biol. Cell, Mar 2012; 23: 800 - 810., 2012 Mar shRNA TR308513
UCHL1 NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's Disease Hum. Mol. Genet., 2015 Feb shRNA TF710038
UCHL1 Expression and Functional Studies of Ubiquitin C-Terminal Hydrolase L1 Regulated Genes PLoS ONE 4(8): e6764 (2009), 2008 Aug shRNA TR316775
UGDH Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential Horm Cancer, 2016 Aug shRNA TG308504
UGT8 Microbubble-based enhancement of radiation effect: Role of cell membrane ceramide metabolism PLoS ONE, 2017 Jul shRNA TG308493