shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Atp5pf Over-Expression of the ATP5J Gene Correlates with Cell Migration and 5-Fluorouracil Sensitivity in Colorectal Cancer PLoS ONE, 2013 Oct shRNA TL712002
ATP6AP2 (Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations Br. J. Cancer, 2018 Dec shRNA TR314574
ATP7A A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity J. Biol. Chem., Dec 2009; 284: 33949 - 33956, 2009 Dec shRNA TR314562
ATP7A Copper transport into the secretory pathway is regulated by oxygen in macrophages J. Cell Sci., May 2009; 122: 1315 - 1321., 2009 May shRNA TR314562
Atp7a Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes Nature 454, 1142 - 1146 (23 Jul 2008), doi: 10.1038/nature07163, Letter, 2008 Aug shRNA TR314562
ATP7B Copper ions are novel therapeutic agents for uterine leiomyosarcoma Am. J. Obstet. Gynecol., 2019 Jul shRNA TF314561
AURKA A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport Cell reports, 2019 Nov shRNA TL320538
AURKA Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells Cancer Biology & Therapy, 2014 Nov shRNA TR320538
AURKB Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells Cancer Biology & Therapy, 2014 Nov shRNA TR320607
B2M A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1+ TCRs J. Immunol., 2018 Jan shRNA TR314543
B2M Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors PLoS ONE, 2016 May shRNA TR314543
B3GALNT1 Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor, Globotetraosylceramide Infect. Immun., Nov 2010; 78: 4488 - 4499, 2010 Nov shRNA TR306471
Babam2 Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells Apoptosis, Jan 2014., 2014 Jan shRNA TG505808
BAG3 A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy Cell Death Dis, 2015 Oct shRNA TR314524
BAK1 Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability Mol. Neurobiol., 2015 May shRNA TF712171
BAK1 BAX/BAK–Independent Mitoptosis during Cell Death Induced by Proteasome Inhibition Mol. Cancer Res., Aug 2009; 7: 1268 - 1284, 2009 Aug shRNA TR314515
BAX Secreted frizzled-related protein 5 protects against oxidative stress-induced apoptosis in human aortic endothelial cells via downregulation of Bax J. Biochem. Mol. Toxicol., 2017 Aug shRNA TR306440
BAX Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability Mol. Neurobiol., 2015 May shRNA TF709871
BAZ1B DNA damage response defect in Williams-Beuren syndrome Int. J. Mol. Med., 2017 Mar shRNA TG306439
BAZ1B PLA2G16 represents a switch between entry and clearance of Picornaviridae Nature, 2017 Jan shRNA TG306439
BCDIN3D BCDIN3D regulates tRNAHis 3' fragment processing PLoS Genet., 2019 Jul shRNA TR317908
BCL11B A novel 4-dimensional live-cell imaging system to study leukocyte-endothelial dynamics in ANCA-associated vasculitis Autoimmunity, 2019 Dec shRNA TR306424
Bcl11b Striatal Neurodevelopment Is Dysregulated in Purine Metabolism Deficiency and Impacts DARPP-32, BDNF/TrkB Expression and Signaling: New Insights on the Molecular and Cellular Basis of Lesch-Nyhan Syndrome PLoS ONE, 2014 May shRNA TL515999
BCL2 IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells Sci Rep, 2018 Jan shRNA TG316461
BCL2 Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner J. Allergy Clin. Immunol., 2017 Jul shRNA TR316461
BCL2 Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in BclxL silenced glioma cell lines Molecular carcinogenesis, 2016 Nov shRNA TR316461
BCL2 Parecoxib Protects Mouse Cortical Neurons Against OGD/R Induced Neurotoxicity by Up-Regulating Bcl-2 Neurochem. Res., 2015 Jun shRNA TG316461
Bcl2a1 The Stress-Inducible BCL2A1 Is Required for Ovarian Cancer Metastatic Progression in the Peritoneal Microenvironment Cancers, 2021 Sep shRNA TL712645
BCL2L11 RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy Autophagy, 2015 May shRNA TG306422
BDNF A unique homeostatic signaling pathway links synaptic inactivity to postsynaptic mTORC1 J. Neurosci., 2018 Jan shRNA TG306410
BECN1 Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function J. Mol. Biol., 2019 Jul shRNA TG503112
BECN1 HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells Cell Death Dis, 2018 Sep shRNA TG314484
BECN1 RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy Autophagy, 2015 May shRNA TG314484
BECN1 Beclin-1-p53 interaction is crucial for cell fate determination in embryonal carcinoma cells J. Cell. Mol. Med., 2014 Sep shRNA TF314484
BECN1 Antagonism of tumoral prolactin receptor promotes autophagy-related cell death Cell Rep 488-500 7 2. April 2014, 2014 Apr shRNA SC117750
BECN1 From autophagy to senescence and apoptosis in Angiotensin II-treated vascular endothelial cells APMIS, 2014 Mar shRNA TG314484
BECN1 Enhancement of Autophagy during Lytic Replication by the Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Activator J. Virol., Aug 2010; 84: 7448 - 7458, 2010 Aug shRNA TR314484
BECN1 Eradication of Intracellular Salmonella Typhimurium with a Small-Molecule, Host Cell-Directed Agent Antimicrob. Agents Chemother., Oct 2009; 10.1128/AAC.00555-09, 2009 Oct shRNA TR314484
BID Inhibition of O-GlcNAcase sensitizes apoptosis and reverses bortezomib resistance in mantle cell lymphoma through modification of truncated Bid Mol. Cancer Ther.2017, 2017 Nov shRNA TF314477
BIK Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria Nat Commun, 2017 Oct shRNA TF500209
BIRC5 Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells Cancer Biology & Therapy, 2014 Nov shRNA TR315477
BIRC5 Molecular Chaperone gp96 Is a Novel Therapeutic Target of Multiple Myeloma Clin Cancer Res. 2013 Nov 15;19(22):6242-51, 2013 Nov shRNA TG315477
BIRC5 IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin Blood, Jan 2011; 117: 352 - 361, 2011 Jan shRNA TR315477
BLM ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction. Cells, 2023 Jan shRNA TR314471
BMF Bmf Facilitates Protein Degradation and Reduces Beclin1 Ubiquitination to Inhibit Autophagy Independent of mTOR bioRxiv, 2020 Jan shRNA TR314463
BMI1 Polycomb protein BMI1 regulates osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells downstream of GSK3 Stem Cells Dev., 2016 Apr shRNA TG314462
BMI1 BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair J. Cell Biol., Oct 2010; 191: 45 - 60, 2010 Oct shRNA TR314462
BMP4 BMP4 Upregulation Is Associated with Acquired Drug Resistance and Fatty Acid Metabolism in EGFR-Mutant Non-Small-Cell Lung Cancer Cells Mol Ther Nucleic Acids, 2018 Aug shRNA TF306390
BMP4 Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression OncoImmunology, 2016 Sep shRNA TG516759
BMP4 BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells Mol. Cancer, 2015 Sep shRNA TG516759