shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
CAV1 Aberrant Promoter Methylation of Caveolin-1 Is Associated with Favorable Response to Taxane-Platinum Combination Chemotherapy in Advanced NSCLC PLoS ONE, 2014 Sep shRNA TF314183
CAV1 Cell Entry of Avian Reovirus Follows a Caveolin-1-mediated and Dynamin-2-dependent Endocytic Pathway That Requires Activation of p38 Mitogen-activated Protein Kinase (MAPK) and Src Signaling Pathways as Well as Microtubules and Small GTPase Rab5 Protein J. Biol. Chem., Sep 2011; 286: 30780 - 30794., 2011 Oct shRNA TR314183
Cav1 Cell Entry of Avian Reovirus Follows a Caveolin-1-mediated and Dynamin-2-dependent Endocytic Pathway That Requires Activation of p38 Mitogen-activated Protein Kinase (MAPK) and Src Signaling Pathways as Well as Microtubules and Small GTPase Rab5 Protein The Journal of Biological Chemistry, 2011 Sep shRNA TL500281
CAVIN1 Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma Lab. Invest., 2015 Mar shRNA TR310045
CAVIN1 SDPR induces membrane curvature and functions in the formation of caveolae Nat Cell Biol. 2009 Jul;11(7):807-14., 2009 Jun shRNA TR310045
CAVIN4 MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line PLoS ONE, 2015 Jun shRNA TG315318
Cbfb Functions of Smad Transcription Factors in TGF-ß1-Induced Selectin Ligand Expression on Murine CD4 Th Cells J. Immunol., 2016 Aug shRNA TR500286
CBLN4 Cerebellin 4, a synaptic protein that enhances inhibitory activity and resistance of neurons to Amyloid beta toxicity Neurobiology of Aging, 2014 Nov shRNA TG516844
CBX4 CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage Nucleic Acids Res., Mar 2012; 10.1093/nar/gks222., 2012 Mar shRNA TR314171
CBX8 Upregulated CBX8 promotes cancer metastasis via the WNK2/MMP2 pathway Molecular Therapy - Oncolytics, 2020 Oct shRNA TF317361
CCAR2 ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction. Cells, 2023 Jan shRNA TR303704
Ccl17 Intratumoral IFN-α gene delivery reduces tumor-infiltrating regulatory T cells through the downregulation of tumor CCL17 expression. Cancer gene therapy, 2020 Jul shRNA TL501986
CCL19 CCR7/CCL19 Controls Expression of EDG-1 in T Cells J. Biol. Chem., Apr 2012; 287: 11656 - 11664., 2012 Apr shRNA TR319889
CCN4 WISP1, a Pro-mitogenic, Pro-survival Factor, Mediates Tumor Necrosis Factor- (TNF-)-stimulated Cardiac Fibroblast Proliferation but Inhibits TNF--induced Cardiomyocyte Death J. Biol. Chem., May 2009; 284: 14414 - 14427, 2009 May shRNA TR300454
CCNA2 CCNA2 facilitates epithelial-to-mesenchymal transition via the integrin αvβ3 signaling in NSCLC International Journal of Clinical and Experimental Pathology, 2017 Aug shRNA TL315479
Ccna2 CCN1 induces a reversible epithelial–mesenchymal transition in gastric epithelial cells Laboratory Investigation (10 May 2010) doi:10.1038/labinvest.2010.101 Research Article, 2010 May shRNA TR712084
CCND1 PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition Mol. Carcinog., 2015 Jan shRNA TG305536
CCND3 L-Arginine availability regulates T lymphocyte cell cycle progression Blood. 2007 Feb 15;109(4):1568-73., 2007 Feb shRNA TR320286
CCNI CDK6 is activated by the atypical cyclin I to promote E2F ‐mediated gene expression and cancer cell proliferation Molecular Oncology, 2023 May shRNA TL314135
CCR4 A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer J. Clin. Invest, 2017 Mar shRNA TR314127
CCR4 A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer J. Clin. Invest, 2017 Mar shRNA TR500386
CCR7 The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis Molecular Cancer, 2015 Jan shRNA TF314124
CD109 CD109 plays a role in osteoclastogenesis PLoS ONE Apr2013, 2013 Apr shRNA TG507140
CD2 Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer J. Natl. Cancer Inst., 2013 Nov shRNA TG314102
CD24 Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation Exp. Mol. Med., 2017 Sep shRNA TG321436
CD24 Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents PLoS ONE, 2015 May shRNA TR321436
Cd274 Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth. Oncology reports, 2023 Feb shRNA TL503436
CD274 Inhibition of Tumor Growth and Sensitization to Sunitinib by RNA Interference Targeting Programmed Death-ligand 1 in Mouse Renal Cell Carcinoma RenCa Model Anticancer Res., 2019 Sep shRNA TG314098
CD274 PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation International Journal of Cancer, 2017 Jun shRNA TR314098
CD274 Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: significance in claudin-low breast cancer cells Mol. Cancer, 2015 Aug shRNA TG314098
CD274 Investigating the role of PD-L1 pathway in human ovarian cancer Thesis, 2014 Sep shRNA TG314098
CD276 Role of MYC-miR-29-B7-H3 in Medulloblastoma Growth and Angiogenesis J Clin Med, 2019 Aug shRNA TR317545
CD36 Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: an early event prior to insulin resistance Theranostics, 2020 Jan shRNA TG314090
CD38 Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes J. Cell. Mol. Med., 2013 Nov shRNA TR314088
CD40 Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation Cytokine, 2019 Jan shRNA TR314082
CD44 CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells Int. J. Oncol, 2017 Jan shRNA TG314080
CD44 Targeting Cancer Stem Cells in Castration-Resistant Prostate Cancer Clin. Cancer Res, 2016 Feb shRNA TG314080
CD44 Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry Nitric Oxide, 2014 Nov shRNA TR314080
CD44 alpha3/4 Fucosyltransferase 3-Dependent Synthesis of Sialyl Lewis A on CD44 Variant Containing Exon 6 Mediates Polymorphonuclear Leukocyte Detachment from Intestinal Epithelium during Transepithelial Migration J Immunol. 2013 Nov 1;191(9):4804-17, 2013 Nov shRNA TG314080
CD44 CD44 Proteolysis Increases CREB Phosphorylation and Sustains Proliferation of Thyroid Cancer Cells Cancer Res., Mar 2012; 72: 1449 - 1458., 2012 Mar shRNA TR314080
CD44 Neutrophil Migration across Intestinal Epithelium: Evidence for a Role of CD44 in Regulating Detachment of Migrating Cells from the Luminal Surface J. Immunol., Dec 2010; 185: 7026 - 7036, 2010 Dec shRNA TR314080
CD44 Stimulation of TLRs by LMW-HA induces self-defense mechanisms in vaginal epithelium Immunology and Cell Biology (23 November 2010) doi:10.1038/icb.2010.140 Original Article, 2010 Nov shRNA TR314080
Cd47 High expression of CD47 predicts adverse prognosis in Chinese patients and suppresses immune response in melanoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018 Apr shRNA TL501123
CD9 Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion Sci Rep, 2018 Jun shRNA TR314060
CD9 Different states of integrin LFA-1 aggregation are controlled through its association with tetraspanin CD9 Biochim. Biophys. Acta, 2015 May shRNA TR314060
CDC42 Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression Nat Commun, 2019 Jan shRNA TG305497
Cdc42 Integrating transient cellular and nuclear motions to comprehensively describe cell migration patterns Sci Rep, 2018 Jan shRNA TF510719
CDC42 IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway J. Cell Sci., Jun 2009; 122: 2024 - 2033, 2009 Jun shRNA TR305497
CDC73 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Oct 2012; 209: 2099 - 2111., 2012 Oct shRNA TG305495
CDC73 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Sep 2012; 10.1084/jem.20112145., 2012 Sep shRNA TR305495