ORF Clones Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Icam1 A novel Fc-engineered human ICAM-1/CD54 antibody with potent anti-myeloma activity developed by cellular panning of phage display libraries Oncotarget, 2017 Sep ORF Clones MC218184
ICAM1 Release of VSVG-pseudotyped Lentivirus from the Host Cell is impaired upon Low-density Lipoprotein Receptor Overexpression J. Virol., 2015 Sep ORF Clones RC200714
Icam1 The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility J. Cell Biol., 2015 Feb ORF Clones MR227081
ICOS ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models PLoS ONE, 2020 Sep ORF Clones MR202040
ICOS Inclusion of Dap10 or 4-1BB costimulation domains in the chPD1 receptor enhances anti-tumor efficacy of T cells in murine models of lymphoma and melanoma Cell. Immunol., 2020 Feb ORF Clones MR202040
ICOS Ligand Loss of human ICOSL results in combined immunodeficiency J. Exp. Med., 2018 Dec ORF Clones RC208975
ICOSL Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion eLife, 2021 Jan ORF Clones MR204667
ICOSLG ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells Sci Rep, 2017 Mar ORF Clones RG208975
ID1 Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin Cell Rep, 2018 Feb ORF Clones RC202061
ID1 microRNA-381 suppresses the growth and increases cisplatin sensitivity in non-small cell lung cancer cells through inhibition of nuclear factor-κB signaling Biomed. Pharmacother., 2017 Dec ORF Clones RG202061
ID2 Inflammation-induced Id2 promotes plasticity in regulatory T cells Nat Commun, 2018 Nov ORF Clones MR200792
ID2 Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin Cell Rep, 2018 Feb ORF Clones RC205324
ID2 Expression Pattern of Id Proteins in Medulloblastoma Pathology oncology research : POR, 2014 Jul ORF Clones RC205324
ID3 Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin Cell Rep, 2018 Feb ORF Clones RC200583
ID4 miRNA-342 regulates CEACAM1-induced lumen formation in a 3D model of mammary gland morphogenesis Journal of Biological Chemistry, 2016 Aug ORF Clones RC204170
IDE Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease Autophagy, 2016 Mar ORF Clones RG220700
IDH1 Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors Nature Cancer, 2022 Jun ORF Clones RC400096
IDH1 Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors Nature Cancer, 2022 Jun ORF Clones SC116430
IDH1 Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection Nature nanotechnology, 2021 Feb ORF Clones RC400096
IDH1 G-CSF Secreted by Epigenetically Reprogrammed Mutant IDH1 Glioma Stem Cells Reverses the Myeloid Cells’-Mediated Immunosuppressive Tumor Microenvironment bioRxiv, 2020 Jul ORF Clones RC400096
IDH1 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors J. Med. Chem., 2019 Jun ORF Clones RC400096
IDH1 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors J. Med. Chem., 2019 Jun ORF Clones RC400097
IDH1 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors J. Med. Chem., 2019 Jun ORF Clones RC400098
IDH1 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors J. Med. Chem., 2019 Jun ORF Clones RC400099
IDH1 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective and Orally Bioavailable mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors J. Med. Chem., 2019 Jun ORF Clones RC400100
IDH1 Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation Elife, 2016 Mar ORF Clones RC400096
IDH1 On the Utility of Short Echo Time (TE) Single Voxel 1H–MRS in Non–Invasive Detection of 2–Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel PLoS ONE, 2016 Jan ORF Clones RG210582
IDH1 Mutant IDH inhibits HNF4α to block hepatocyte differentiation and promote biliary cancer Nature, 2015 Jul ORF Clones RG210582
IDH1 IDH1 and IDH2 mutations in pediatric acute leukemia Leukemia, 2014 Jan ORF Clones RG210582
IDH1 An R132H Mutation in Isocitrate Dehydrogenase 1 Enhances p21 Expression and Inhibits Phosphorylation of Retinoblastoma Protein in Glioma Cells Neurologia medico-chirurgica, 2013 Oct ORF Clones RG210582
IDH2 H2A.Z-dependent and-independent recruitment of metabolic enzymes to chromatin required for histone modifications bioRxiv, 2019 Feb ORF Clones RG201152
IDH2 Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate Elife, 2017 Jun ORF Clones RC201152
IDH2 Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate Elife, 2017 Jun ORF Clones RC400103
IDH2 IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity Cancer Research, 2016 Oct ORF Clones RC201152
IDH2 Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation eLife, 2016 Mar ORF Clones RC400103
IDH2 Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate Elife, 2016 Mar ORF Clones RC201152
IDH2 Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate Elife, 2016 Mar ORF Clones RC400103
IDH2 Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation Elife, 2016 Mar ORF Clones RC201152
IDH2 Metabolomic comparison between cells overexpressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism J. Neurochem., 2014 Sep ORF Clones RC201152
IDH2 Elevated CO2 Levels Cause Mitochondrial Dysfunction and Impair Cell Proliferation J. Biol. Chem., Oct 2011; 286: 37067 - 37076., 2011 Oct ORF Clones RC201152
IDO1 Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia Cancer discovery, 2022 Jan ORF Clones RC206592
IDO1 YIV-906 Potentiated anti-PD1 Action Against Hepatocellular Carcinoma by Enhancing Adaptive and Innate Immunity in the Tumor Microenvironment. Research Square, 2021 Mar ORF Clones MR206394
IDO1 Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors Journal of medicinal chemistry, 2021 Feb ORF Clones RC206592
IDO1 Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine Nat Commun, 2020 Aug ORF Clones RG206592
IDO1 Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4 J. Exp. Med., Jun 2013; 210: 1389 - 1402., 2013 Jun ORF Clones RG206592
Iduronate 2 sulfatase Newborn Screening Program for Mucopolysaccharidosis Type II and Long-Term Follow-Up of the Screen-Positive Subjects in Taiwan Journal of Personalized Medicine, 2022 Jun ORF Clones RC219187
Iduronate 2 sulfatase Identification and Functional Characterization of IDS Gene Mutations Underlying Taiwanese Hunter Syndrome (Mucopolysaccharidosis Type II) Int J Mol Sci, 2019 Dec ORF Clones RC219187
IF3EI Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation Nat Commun, 2018 May ORF Clones RC206690
IFI16 IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP Elife, 2019 Nov ORF Clones RC202193
IFI16 Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes Sci Rep, 2016 May ORF Clones RC202193