shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
CDH1 Downregulation of E-cadherin is an essential event in activating bold beta-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells Oncogene advance online publication 28 September 2009; doi: 10.1038/onc.2009.302, 2009 Sep shRNA TR314042
CDH11 Reciprocal regulation of the Cadherin-11/Stat3 axis by caveolin-1 in mouse fibroblasts and lung carcinoma cells Biochim. Biophys. Acta, 2018 Feb shRNA TF509242
CDH2 Specific N-cadherin-dependent pathways drive human breast cancer dormancy in bone marrow Life science alliance, 2021 Jul shRNA TF314034
CDH2 The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction Sci Rep, 2018 Feb shRNA HC138304
CDH26 Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity Cell Discov, 2018 Feb shRNA TF305478
Cdh3 A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration Developmental cell, 2023 Jan shRNA TL500332
CDH3 A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration Developmental cell, 2023 Jan shRNA TL314033
CDH3 HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherin Mol. Cancer July 2014, 2014 Jul shRNA TG314033
CDIP1 Expression of the p53 Target CDIP Correlates with Sensitivity to TNFa-Induced Apoptosis in Cancer Cells Cancer Res., May 2012; 72: 2373 - 2382., 2012 May shRNA TR315650
CDK4 Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways PLoS ONE, 2015 Aug shRNA TG320293
CDK5 The HU177 Collagen Epitope Controls Melanoma Cell Migration and Experimental Metastasis by a CDK5/YAP-Dependent Mechanism Am. J. Pathol., 2018 Aug shRNA TG515615
CDKN1A Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer Cell death & disease, 2020 Dec shRNA TG305469
CDKN1A 15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE2/PPAR?-mediated activation of p21WAF1/Cip1 Oncogene doi:10.1038/onc.2013.69, 2013 Apr shRNA TG305469
CDKN1A Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models Mol. Cancer Ther., Feb 2009; 8: 342 - 349, 2009 Feb shRNA TR305469
CDKN1A Enhanced Antitumor Therapy by Inhibition of p21waf1 in Human Malignant Mesothelioma Clin. Cancer Res., Aug 2008; 14: 5099 - 5107, 2008 Aug shRNA TR305469
CDKN1B Kaposi's Sarcoma-Associated Herpesvirus Transactivator Rta Induces Cell Cycle Arrest in G0/G1 Phase by Stabilizing and Promoting Nuclear Localization of p27kip J. Virol. 13226-38, 2013 Nov shRNA TR314022
CDKN1B KSHV encoded Rta induces cell cycle arrest J. Virol. Dec 2013., 2013 Sep shRNA TG314022
CDKN2B Runx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivo PNAS, Mar 2013; 110: 4634 - 4639., 2013 Mar shRNA TG320299
CEBPA Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells PLoS ONE, 2015 Sep shRNA TF316491
CEBPB Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer Journal of Experimental & Clinical Cancer Research : CR, 2022 Aug shRNA TL320301
CEBPB A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer\'s disease pathologies Brain : a journal of neurology, 2021 Apr shRNA TR710974
Cebpb Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell reports, 2019 Aug shRNA TF500345
Cebpd Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell reports, 2019 Aug shRNA TF500346
CEL Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma Oncogene, 2016 May shRNA TR313998
Cela1 Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development American Journal of Physiology - Lung Cellular and Molecular Physiology, 2015 Jun shRNA TL709197
CELF1 Translational derepression of Elavl4 isoforms at their alternative 5\' UTRs determines neuronal development Nat Commun, 2020 Apr shRNA TF514753
Celf1 Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines Mol. Biol. Cell, Sep 2011; 22: 3055 - 3069., 2011 Oct shRNA TR514753
CENPB A two-step mechanism for epigenetic specification of centromere identity and function Nature Cell Biology doi:10.1038/ncb2805, 2013 Jul shRNA TG313993
CENPJ Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1 Nat Commun, 2015 Mar shRNA TG305452
CEP55 Suppression of CEP55 reduces cell viability and induces apoptosis in human lung cancer Oncol. Rep., 2016 Oct shRNA TR305437
CEPT1 Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets Nature communications, 2020 Sep shRNA TR313975
CFLAR Esophageal cancer cells convert the death signal from TRAIL into a stimulus for survival during acid/bile exposure Digestive and Liver Disease, 2020 Jun shRNA TR313960
CFLAR Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates Nat. Med, 2017 Feb shRNA TG500356
CFLAR TNF Apoptosis Protection Fraction (TAPF) prevents apoptosis induced by TNF, but not by Fas or TRAIL, via NF-?B-induced increase in cFLIP Cytokine, 2015 Jul shRNA TR313960
CFLAR Inhibition of NF-{kappa}B Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin J. Biol. Chem., Jun 2010; 285: 19162 - 19172, 2010 Jun shRNA TR313960
CFTR High CFTR expression in Philadelphia chromosome-positive acute leukemia protects and maintains continuous activation of BCR-ABL and related signaling pathways in combination with PP2A Oncotarget, 2017 Apr shRNA TG313958
CFTR High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo Oncol. Rep., 2015 May shRNA TG313958
CGAS Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes. JCI insight, 2022 Aug shRNA TL305813
CHCHD3 ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function J. Biol. Chem., Jan 2011; 286: 2918 - 2932, 2011 Jan shRNA TR305418
CHCHD4 Glutathionylated and Fe-S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain Redox biology, 2020 Sep shRNA TG305417
CHCHD4 Human Mitochondrial MIA40 (CHCD4) is a component of Fe/S cluster export machinery Biochem. J., 2015 Aug shRNA TR305417
CHD1 The Role of CHD1 in DNA Rearrangements and Progression of Prostate Cancer Grant, 2013 Jul shRNA TR313946
CHD4 CHD4 Predicts Aggressiveness in PTC Patients and Promotes Cancer Stemness and EMT in PTC Cells International journal of molecular sciences, 2021 Jan shRNA TR313943
CHEK1 Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma Translational Oncology, 2017 Dec shRNA TR320302
CHI3L1 YKL-40 regulated epithelial-mesenchymal transition and migration/invasion enhancement in non-small cell lung cancer BMC Cancer, 2015 Aug shRNA TR316497
CHPT1 Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets Nature communications, 2020 Sep shRNA TR305398
CHRM3 Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression Int. Immunopharmacol., 2015 May shRNA TR313926
CHRM4 Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression Int. Immunopharmacol., 2015 May shRNA TR313925
CHRNA3 Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression Int. Immunopharmacol., 2015 May shRNA TR313921
CHRNA3 Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors BMC Cancer, 2015 Mar shRNA TG313921