siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
COMMD1 Copper metabolism domain-containing 1 represses the mediators involved in the terminal effector pathways of human labour and delivery Mol. Hum. Reprod., 2016 Jan siRNA SR315744
COMT Suppressor effect of catechol-O-methyltransferase gene in prostate cancer PLoS ONE, 2021 Sep siRNA SR319770
control siRNA Low Dose Ultraviolet B Irradiation Increases Hyaluronan Synthesis in Epidermal Keratinocytes via Sequential Induction of Hyaluronan Synthases Has1–3 Mediated by p38 and Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) Signaling J. Biol. Chem., Jun 2013; 288: 17999 - 18012., 2013 Jun siRNA SR30004
CONTROL VECTOR iTRAQ‑based proteomic analysis of the interaction of A549 human lung epithelial cells with Aspergillus fumigatus conidia Mol Med Rep, 2020 Oct siRNA SR30004
COPB2 Upregulation of the Coatomer Protein Complex Subunit beta 2 (COPB2) Gene Targets microRNA-335-3p in NCI-H1975 Lung Adenocarcinoma Cells to Promote Cell Proliferation and Migration Med. Sci. Monit., 2020 Jan siRNA SR306142
COPB2 COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells Biomed. Pharmacother., 2018 Jul siRNA SR306142
COX5A Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism Nucleic Acids Research, 2020 Dec siRNA SR306213
CPEB2 Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells BMC Cancer, 2019 Jun siRNA SR315168
CREB3 Involvement of Akt-dependent CREB signaling pathway in hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-induced early growth response protein-1 (Egr-1) expression in vascular smooth muscle cells Can. J. Physiol. Pharmacol., 2019 Apr siRNA SR500635
CREB3 STIM-1 and ORAI-1 Channel Mediate Angiotensin-II-Induced Expression of Egr-1 in Vascular Smooth Muscle Cells J. Cell. Physiol, 2017 Jan siRNA SR500635
CREM The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis Pediatr Rheumatol Online J, 2018 Jun siRNA SR300979
CRKL Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration Sci Rep, 2020 Jan siRNA SR300987
CRKL Escherichia coli virulence protein NleH1 interaction with the v-crk sarcoma virus CT10 oncogene-Like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/NF-kappaB pathway J Biol Chem. 2013 Oct 21, 2013 Oct siRNA SR300987
CSA Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA Proc. Natl. Acad. Sci. U.S.A., 2016 Nov siRNA SR300835
CSB Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA Proc. Natl. Acad. Sci. U.S.A., 2016 Nov siRNA SR301453
CSF1R Osteosarcoma cell-intrinsic colony stimulating factor-1 receptor functions to promote tumor cell metastasis through JAG1 signaling Am J Cancer Res, 2017 May siRNA SR301013
CSMD1 Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy Sci Rep, 2019 Aug siRNA SR312062
CSMD3 Systematic Discovery of the Functional Impact of Somatic Genome Alterations in Individual Tumors through Tumor-specific Causal Inference bioRxiv, 2018 May siRNA SR314432
CSNK1A1 Casein kinase 1α mediates degradation of receptors for type I and type II interferons caused by hemagglutinin of influenza A virus J. Virol., 2018 Jan siRNA SR319812
CSTF2 Alternative polyadenylation factors link cell cycle to migration Genome Biol., 2018 Oct siRNA SR301049
CSTF2 CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3' end processing Nucleic Acids Res., 2014 Jun siRNA SR301049
CSTF3 The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity Nucleic Acids Res., 2018 Sep siRNA SR301050
CT55 Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance. Mitochondrion, 2022 Apr siRNA SR310386
CTCF DNA Methylation Profiling in Human Huntington's Disease Brain Hum. Mol. Genet., 2016 Mar siRNA SR307273
CTCF Identification of CTCF as a master regulator of the clustered protocadherin genes Nucleic Acids Res., Apr 2012; 40: 3378 - 3391., 2012 Apr siRNA SR307273
CTNNA3 Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy J. Immunol., 2015 Jul siRNA SR309217
CTNNB1 1,25(OH)2D3 inhibits osteogenic differentiation through activating β‑catenin signaling via downregulating bone morphogenetic protein 2 Mol Med Rep, 2020 Oct siRNA SR500644
CTNNB1 Heterogeneous nuclear ribonucleoprotein M promotes the progression of breast cancer by regulating the axin/β-catenin signaling pathway Biomedicine & Pharmacotherapy, 2018 Sep siRNA SR319832
CTNNB1 CHI3L1 results in poor outcome of ovarian cancer by promoting properties of stem-like cells Endocr. Relat. Cancer, 2018 Aug siRNA SR319832
CTNNB1 A novel microRNA regulator of prostate cancer epithelial-mesenchymal transition Cell Death Differ., 2017 May siRNA SR301063
CTNNB1 Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer Nat Commun, 2016 Feb siRNA SR301063
CTNNB1 Altered Protease-Activated Receptor-1 Expression and Signaling in a Malignant Pleural Mesothelioma Cell Line, NCI-H28, with Homozygous Deletion of the ß-Catenin Gene PLoS ONE, 2014 Nov siRNA SR301063
CTNNBIP1 The Alteration of CTNNBIP1 in Lung Cancer Int J Mol Sci, 2019 Nov siRNA SR311306
CTNNBL1 Spliceosome-associated factor catenin b-like 1 accelerates ovarian cancer progression by inducing expression and nuclear accumulation of yes-associated protein Int J Clin Exp Med, 2019 Jan siRNA SR311144
CTRL A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells Stem Cells, 2014 Aug siRNA SR301068
CTTN Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection Mol. Cell, 2018 Dec siRNA SR427044
Cttn Inhibition of stress fiber formation preserves blood-brain barrier after intracerebral hemorrhage in mice J. Cereb. Blood Flow Metab., 2016 Nov siRNA SR416350
CTTN PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk Acta Neuropathol., 2015 Sep siRNA SR301402
CUL1 TRIM26 Negatively Regulates Interferon-ß Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3 PLoS Pathog., 2015 Mar siRNA SR305540
CUL3 WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4 Sci Rep, 2018 Jun siRNA SR419963
CUL4A Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma PLoS ONE, 2015 Dec siRNA SR305537
CUTC Silencing of Human CutC Gene (hCutC) Induces Apoptosis in HepG2 Cells Biol Trace Elem Res, 2015 Dec siRNA SR309512
Cx3cl1 Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction Nature Communications, 2022 Dec siRNA SR426672
CXCL9 CXCL9 promotes the progression of diffuse large B-cell lymphoma through up-regulating β-catenin Biomed. Pharmacother., 2018 Aug siRNA SR302901
CXCR3 The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) Int J Mol Sci, 2019 Oct siRNA SR301896
CXCR4 Disease mechanism, drug-target and biomarker prediction software: Application on prostate cancer and validation bioRxiv, 2019 Dec siRNA SR322283
CXCR4 CXCL12/CXCR4 Axis Activation Mediates Prostate Myofibroblast Phenoconversion through Non-Canonical EGFR/MEK/ERK Signaling PLoS ONE, 2016 Jul siRNA SR322283
Cy-3-labeled control siRNA cAMP-responsive Element Modulator a (CREMa) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE) J. Biol. Chem., Feb 2012; 287: 4715 - 4725., 2012 Feb siRNA
CYBB Nox2-mediated PI3K and Cofilin Activation Confers Alternate Redox Control of Macrophage Pinocytosis Antioxid. Redox Signal., 2016 Aug siRNA SR301088
CYCS Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts Cell Death Dis, 2020 May siRNA SR401266