shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Identification of NEK3 Threonine 165 as a Novel Regulatory Phosphorylation Site that Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration J. Biol. Chem., 2016 Aug shRNA TR30014
Identification of NEK3 Threonine 165 as a Novel Regulatory Phosphorylation Site that Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration J. Biol. Chem., 2016 Aug shRNA TR30015
Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential Horm Cancer, 2016 Aug shRNA TR30008
IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories Development, 2016 Aug shRNA TR30012
Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis Nat Commun, 2016 Jul shRNA TR30012
Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling Oncogenesis, 2016 Jul shRNA TR20003
High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2 Biochem. Biophys. Res. Commun., 2016 Jul shRNA TR30013
Epstein-Barr Virus Oncoprotein LMP1 Mediates Epigenetic Changes in Host Gene Expression through PARP1 J. Virol., 2016 Jul shRNA TR30021
Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells Cancer Cell, 2016 Jun shRNA TR30021
Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR-138 and miR-let-7 in Cranial Neural Crest Cells Stem Cells, 2016 Jun shRNA TR30013
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair EMBO J., 2016 May shRNA TR30003
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair EMBO J., 2016 May shRNA TR30012
Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma Oncogene, 2016 May shRNA TR30012
Characterization of SKAP/Kinastrin isoforms - The N-terminus defines tissue specificity and Pontin binding Hum. Mol. Genet., 2016 May shRNA TR30021
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death Sci Rep, 2016 May shRNA TR30013
Upregulation of long noncoding RNA LOC100507661 promotes tumor aggressiveness in thyroid cancer Mol. Cell. Endocrinol., 2016 May shRNA Custom shRNA for ncRNA
Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells PLoS ONE, 2016 May shRNA TR30013
HMGB1 knockdown effectively inhibits the progression of rectal cancer by suppressing HMGB1 expression and promoting apoptosis of rectal cancer cells Mol Med Rep, 2016 May shRNA TR30013
OCT-4: a novel estrogen receptor-a collaborator that promotes tamoxifen resistance in breast cancer cells Oncogene, 2016 Apr shRNA TR30021
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1 Nature Communications, 2016 Apr shRNA TR30021
Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration Free Radic. Biol. Med., 2016 Apr shRNA TR20003
Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration Free Radic. Biol. Med., 2016 Apr shRNA TR30003
Regulación del Uniportador de Calcio Mitocondrial por MICU1 y MICU2 thesis, 2016 Apr shRNA TR30014
Inhibition of the Expression of the Small Heat Shock Protein aB-crystallin Inhibits Exosome Secretion in Human Retinal Pigment Epithelial Cells in Culture J. Biol. Chem., 2016 Apr shRNA TR30007
CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor Oncogene, 2016 Apr shRNA TR30013
Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart Aging (Albany NY), 2016 Mar shRNA TR30023
aCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome Nucleic Acids Res., 2016 Mar shRNA TR30007
Development of a novel HAC-based gain of signal quantitative assay for measuring chromosome instability (CIN) in cancer cells Oncotarget, 2016 Mar shRNA TR30007
Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone Neurobiol. Dis., 2016 Mar shRNA TR20003
NF-YA splice variants have different roles on muscle differentiation Biochim. Biophys. Acta, 2016 Feb shRNA TR30021
IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs Oncotarget, 2016 Feb shRNA TR30007
MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo. Cancer letters, 2015 Oct shRNA TR30013
A Conserved Function in Phosphatidylinositol Metabolism for Mammalian Vps13 Family Proteins PLoS ONE, 2015 Apr shRNA TR30015
Der Einfluss des Mismatch Reparaturfaktors hMSH2 auf distinkte Reparaturwege der DNA Doppelstrangbruch Reparatur thesis, 2015 Feb shRNA TR30012
Synergistic restoring effects of isoproterenol and magnesium on KCNQ1-inhibited bradycardia cell models cultured in microelectrode array. Cardiology, 2015 Jan shRNA TR30013
KIF20A-Mediated RNA Granule Transport System Promotes the Invasiveness of Pancreatic Cancer Cells Neoplasia (New York, N.Y.), 2014 Dec shRNA TR30013
VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2–dependent Ca 2+ signaling Proceedings of the National Academy of Sciences of the United States of America, 2014 Nov shRNA TR30012
The Transcription Factor GLI1 Interacts with SMAD Proteins to Modulate Transforming Growth Factor β-Induced Gene Expression in a p300/CREB-binding Protein-associated Factor (PCAF)-dependent Manner The Journal of Biological Chemistry, 2014 May shRNA TR30013
Autophagic Clearance of Mitochondria in the Kidney Copes with Metabolic Acidosis Journal of the American Society of Nephrology : JASN, 2014 Apr shRNA TR30012
Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3σ. Journal of cell science, 2013 Nov shRNA TR30013
APLP2 regulates neuronal stem cell differentiation during cortical development. Journal of cell science, 2013 Oct shRNA TR30012
miR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma PLoS ONE, 2013 Feb shRNA TR30013
Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2. European journal of immunology, 2012 Aug shRNA TR30003
Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation Carcinogenesis, 2012 Jul shRNA TR30003
Estrogenic transmembrane receptor of GPR30 mediates invasion and carcinogenesis by endometrial cancer cell line RL95-2. Journal of cancer research and clinical oncology, 2012 Jun shRNA TR30003
Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells. Journal of cellular biochemistry, 2012 Jun shRNA TR30012
B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes. International journal of cancer, 2012 May shRNA TR30003
Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation. Oncogene, 2012 May shRNA TR30003
The G protein-coupled receptor GPR30 mediates the proliferative and invasive effects induced by hydroxytamoxifen in endometrial cancer cells. Biochemical and biophysical research communications, 2012 May shRNA TR30003
The bone morphogenetic protein antagonist Gremlin is overexpressed in human malignant mesothelioma. Oncology reports, 2012 Feb shRNA TR30012