shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. Journal of neurochemistry, 2012 Feb shRNA TR30013
Endogenous hydrogen sulfide is involved in asymmetric dimethylarginine-induced protection against neurotoxicity of 1-methyl-4-phenyl-pyridinium ion. Neurochemical research, 2012 Jan shRNA TR30012
Proteomic analysis of testis biopsies in men treated with transient scrotal hyperthermia reveals the potential targets for contraceptive development. Proteomics, 2011 Jan shRNA TR30003
Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop Molecular Biology of the Cell, 2010 Apr shRNA TR30003
Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components Proceedings of the National Academy of Sciences of the United States of America, 2010 Feb shRNA TR30003
Estrogenic G protein-coupled receptor 30 signaling is involved in regulation of endometrial carcinoma by promoting proliferation, invasion potential, and interleukin-6 secretion via the MEK/ERK mitogen-activated protein kinase pathway. Cancer science, 2009 Jul shRNA TR30003
Telomerase reverse transcriptase regulates the expression of a key cell cycle regulator, cyclin D1. Biochemical and biophysical research communications, 2006 Sep shRNA TR30003
ABCB1 Targeted co-delivery of paclitaxel and anti P-gp shRNA by low molecular weight PEI decorated with L-3,4-dihydroxyphenylalanine. Biotechnology progress, 2023 Apr shRNA TF315032
ABCB1 Temozolomide competes for P-glycoprotein and contributes to chemoresistance in glioblastoma cells Cancer Lett., 2015 Jul shRNA TF315032
ABCC4 Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer Oncotarget, 2017 Jan shRNA TR315025
ABCC6 Dysregulation of gene expression in ABCC6 knockdown HepG2 cells Cell. Mol. Biol. Lett., 2014 Aug shRNA TR315023
ABCG2 Silencing growth hormone receptor inhibits estrogen receptor negative breast cancer through ATP-binding cassette sub-family G member 2 Exp. Mol. Med., 2019 Jan shRNA TR315016
Abhd6 Serine Hydrolase Inhibitors Block Necrotic Cell Death by Preventing Calcium Overload of the Mitochondria and Permeability Transition Pore Formation J. Biol. Chem. Dec 2013., 2013 Dec shRNA TG306904
ABI1 PTEN dephosphorylates Abi1 to promote epithelial morphogenesis J. Cell Biol., 2020 Sep shRNA TG513768
Abi1 PTEN dephosphorylates Abi1 to promote epithelial morphogenesis The Journal of Cell Biology, 2020 Sep shRNA TL513768
ABI1 PTEN suppresses epithelial-mesenchymal transition and cancer stem cell activity by downregulating Abi1 Sci Rep, 2020 Jul shRNA TF315014
ABI2 PTEN dephosphorylates Abi1 to promote epithelial morphogenesis J. Cell Biol., 2020 Sep shRNA TF508429
Abi2 PTEN dephosphorylates Abi1 to promote epithelial morphogenesis The Journal of Cell Biology, 2020 Sep shRNA TL508429
ACKR2 A novel ACKR2-dependent role of fibroblast-derived CXCL14 in epithelial-to-mesenchymal transition and metastasis of breast cancer Clin. Cancer Res., 2019 Mar shRNA TF503412
ACKR3 CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment Tumour Biol., 2017 May shRNA TR305345
ACKR3 The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation Mol. Cancer, 2014 Aug shRNA TR305345
ACKR3 Use of shRNA for Stable Suppression of Chemokine Receptor Expression and Function in Human Cancer Cell Lines Methods Mol. Biol., 2014 Jun shRNA TG305345
ACLY ATP-Citrate Lyase Reduction Mediates Palmitate-induced Apoptosis in Pancreatic Beta Cells J. Biol. Chem., Oct 2010; 285: 32606 - 32615, 2010 Oct shRNA TR505684
ACP5 ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma Oncogene doi:10.1038/onc.2013.90, 2013 Apr shRNA TG314985
ACTN4 Alpha-actinin-4 is Required for Amoeboid-type Invasiveness of Melanoma Cells J. Biol. Chem., 2014 Oct shRNA TG314967
ACVRL1 The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes Cell. Mol. Biol. Lett., 2014 Dec shRNA TG710699
ADAM12 A disintegrin and metalloprotease 12 contributes to colorectal cancer metastasis by regulating epithelial-mesenchymal transition International Journal of Oncology, 2023 Apr shRNA TL306850
ADAM8 ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells Int. J. Cancer, 2017 Oct shRNA TF314948
ADAM8 ADAM8 as a drug target in pancreatic cancer Nat Commun, 2015 Jan shRNA TF314948
Adamts12 Identification of relevant genetic alterations in cancer using topological data analysis Nature Communications, 2020 Jul shRNA TL510190
ADAMTS15 Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer Cancer Res., Jun 2009; 69: 4926 - 4934, 2009 Jun shRNA TR306839
ADAR ADAR1 restricts LINE-1 retrotransposition Nucleic Acids Res., 2016 Sep shRNA TG306828
ADAR Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma Nature Medicine 19, 209-216 doi:10.1038/nm.3043, 2013 Jan shRNA TG306828
Adcy5 Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation J. Cell Sci., Jan 2012; 125: 176 - 188., 2012 Jan shRNA TG506651
Adcyap1 Age-Related Decline of Autocrine Pituitary Adenylate Cyclase-Activating Polypeptide Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells J. Gerontol. A Biol. Sci. Med. Sci., 2014 Aug shRNA TR709809
ADIPOR1 Underactivation of the adiponectin-adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression Clin Exp Metastasis. 2013 Oct 5, 2013 Oct shRNA TG306815
ADM2 Adrenomedullin2 (ADM2)/Intermedin (IMD): A potential role in the pathophysiology of Preeclampsia J. Clin. Endocrinol. Metab., 2016 Sep shRNA TR306813
ADORA2A Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy J. Clin. Invest., 2017 Mar shRNA TF314920
ADPRH Role of a TRIM72 ADP-ribosylation cycle in myocardial injury and membrane repair JCI Insight, 2018 Nov shRNA TG512261
ADRB2 Housing temperature-induced stress drives therapeutic resistance in murine tumour models through ß2-adrenergic receptor activation Nat Commun, 2015 Mar shRNA TG314911
ADRM1 Regulation of NF-{kappa}B activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13) PNAS, Aug 2010; 107: 13854 - 13859, 2010 Aug shRNA TR306807
AGBL3 Structural modeling and functional characterization of mammalian cytosolic carboxypeptidases 2 and 3 Thesis, 2014 Sep shRNA TG318365
Ager RAGE ablation attenuates glioma progression and enhances tumor immune responses by suppressing galectin-3 expression. Neuro-oncology, 2023 May shRNA TL515756
AGXT In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis Cell Rep, 2016 May shRNA TR314885
Ahnak Neurite outgrowth induced by NGF or L1CAM via activation of the TrkA receptor is sustained also by the exocytosis of enlargeosomes Proc. Natl. Acad. Sci. U.S.A., 2014 Nov shRNA TR514924
Ahnak2 AHNAK2 Participates in the Stress-Induced Nonclassical FGF1 Secretion Pathway J. Cell. Biochem., 2015 Jan shRNA TG512658
AHR The aryl hydrocarbon receptor is a novel negative regulator of interleukin-17-mediated signaling and inflammation in vitro FEBS Lett., 2019 Apr shRNA TG320259
AHR Interleukin-24 as a target cytokine of environmental aryl hydrocarbon receptor agonist exposure in the lung Toxicol. Appl. Pharmacol, 2017 Mar shRNA TR320259
AHR Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER){alpha} Protein Degradation in Breast Cancer Cells Disrupting an ER{alpha}-GATA3 Transcriptional Cross-Regulatory Loop Mol. Biol. Cell, Apr 2010; 21: 1166 - 1177, 2010 Apr shRNA TR320259
AHRR Wood Smoke Enhances Cigarette Smoke-Induced Inflammation by Inducing the Aryl Hydrocarbon Receptor Repressor in Airway Epithelial Cells Am. J. Respir. Cell Mol. Biol., 2014 Aug shRNA TR306787