siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
USP1 A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer iScience, 2020 Aug siRNA SR305052
USP1 A Non-genetic Mechanism for Chemoresistance in Lung Cancer: The Role of Integrin β4/Paxillin Axis bioRxiv, 2019 Sep siRNA SR305052
USP18 Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18 Alcohol. Clin. Exp. Res., 2016 Nov siRNA SR307736
USP34 Inhibition of ubiquitin-specific protease 34 (USP34) induces epithelial-mesenchymal transition and promotes stemness in mammary epithelial cells Cell. Signal., 2017 Aug siRNA SR400002
USP4 The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function Oncogenesis, 2017 Jun siRNA SR305038
USP7 The deubiquitinating enzyme USP7 regulates the transcription factor Nrf1 by modulating its stability in response to toxic metal exposure The Journal of biological chemistry, 2021 Apr siRNA SR305301
USP8 Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion Cancer Manag Res, 2020 Mar siRNA SR306014
USP8 Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer Nat Commun, 2016 Jun siRNA SR306014
USP9X BAG3-mediated Mcl-1 stabilization contributes to drug resistance via interaction with USP9X in ovarian cancer. International journal of oncology, 2017 Mar siRNA SR305407
UTP4 Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA Proc. Natl. Acad. Sci. U.S.A., 2016 Nov siRNA SR313737
VANGL2 Syndecan-4 controls lymphatic vasculature remodeling during embryonic development Development, 2016 Oct siRNA SR311428
VASP The PKGIα/VASP pathway is involved in insulin- and high glucose-dependent regulation of albumin permeability in cultured rat podocytes J. Biochem., 2020 Jun siRNA SR515513
VDAC1 A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer iScience, 2020 Aug siRNA SR305067
VDAC1 A Non-genetic Mechanism for Chemoresistance in Lung Cancer: The Role of Integrin β4/Paxillin Axis bioRxiv, 2019 Sep siRNA SR305067
VDR Inhibition of Antiestrogen-Promoted Pro-Survival Autophagy and Tamoxifen Resistance in Breast Cancer through Vitamin D Receptor Nutrients, 2021 May siRNA SR322180
VDR Vitamin D attenuates cerebral artery remodeling through VDR/AMPK/eNOS dimer phosphorylation pathway after subarachnoid hemorrhage in rats J. Cereb. Blood Flow Metab., 2017 Jan siRNA SR508804
VDR Intranasal administration of vitamin D attenuates blood-brain barrier disruption through endogenous upregulation of osteopontin and activation of CD44/P-gp glycosylation signaling after subarachnoid hemorrhage in rats J. Cereb. Blood Flow Metab., 2016 Sep siRNA SR508804
VEGFA MiR-205-5p suppresses angiogenesis in gastric cancer by downregulating the expression of VEGFA and FGF1 Experimental Cell Research, 2021 May siRNA SR322181
VIM Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma Molecular Oncology, 2015 May siRNA SR305078
VRK1 VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis Cell. Mol. Life Sci., 2018 Jan siRNA SR322192
VTCN1 B7-H4 overexpression is essential for early hepatocellular carcinoma progression and recurrence Oncotarget, 2017 Oct siRNA SR312516
VTCN1 B7-H4 expression by nonhematopoetic cells in the tumor microenvironment promotes anti-tumor immunity Cancer Immunol Res, 2014 Dec siRNA SR312516
Wdr1 A Serine/Threonine Kinase 16-Based Phospho-Proteomics Screen Identifies WD Repeat Protein-1 As A Regulator Of Constitutive Secretion Scientific Reports, 2018 Aug siRNA SR510518
WFS1 Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells Sci Rep, 2019 Mar siRNA SR504899
WIPI1 Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation Autophagy, 2011 Dec siRNA SR310458
WIPI2 Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation Autophagy, 2011 Dec siRNA SR308719
WNK1 WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4 Sci Rep, 2018 Jun siRNA SR423399
WNT3A A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells Stem Cells, 2014 Aug siRNA SR313904
WNT5A Decreased DNA methylation in the promoter region of the WNT5A and GDNF genes may promote the osteogenicity of mesenchymal stem cells from patients with ossified spinal ligaments J. Pharmacol. Sci., 2015 Apr siRNA SR305106
WRN PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment Communications Biology, 2023 Mar siRNA SR322215
WRN NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome Nat Commun, 2019 Nov siRNA SR322215
WWOX Inhibition of miR-24 suppresses malignancy of human non-small cell lung cancer cells by targeting WWOX in vitro and in vivo Thorac Cancer, 2018 Oct siRNA SR309942
WWP1 MiR-21 suppresses endothelial progenitor cell proliferation by activating the TGFß signaling pathway via downregulation of WWP1 Int J Clin Exp Pathol, 2015 Jan siRNA SR307565
XBP1 MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer Mol. Cancer, 2014 Oct siRNA SR305120
XIST Overexpression of long non-coding RNA XIST promotes IL-1β-induced degeneration of nucleus pulposus cells through targeting miR-499a-5p Molecular and cellular probes, 2021 Mar siRNA SR305123
XRCC2 Fallopian tube precursor lesions of serous ovarian carcinoma require L1CAM for dissemination and metastasis bioRxiv, 2018 Mar siRNA SR322227
YAP1 Salvianolic acid B ameliorates atherosclerosis via inhibiting YAP/TAZ/JNK signaling pathway in endothelial cells and pericytes Biochim Biophys Acta Mol Cell Biol Lipids, 2020 Jul siRNA SR505344
YAP1 Role of Hippo/YAP signaling in irradiation-induced glioma cell apoptosis Cancer Manag Res, 2019 Aug siRNA SR323110
YAP1 Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo Biomaterials, 2019 Apr siRNA SR323110
YAP1 Spliceosome-associated factor catenin b-like 1 accelerates ovarian cancer progression by inducing expression and nuclear accumulation of yes-associated protein Int J Clin Exp Med, 2019 Jan siRNA SR323110
YAP1 ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM Front. Cell. Neurosci., 2018 Dec siRNA SR323110
YAP1 COPB2 promotes cell proliferation and tumorigenesis through up-regulating YAP1 expression in lung adenocarcinoma cells Biomed. Pharmacother., 2018 Jul siRNA SR323110
YAP1 Poly(rC)-binding Protein 2 regulates Hippo signaling to control growth in breast epithelial cells Mol. Cell. Biol., 2016 May siRNA SR307060
YBX1 IL-27 posttranslationally regulates Y-box binding protein-1 to inhibit HIV-1 replication in human CD4+ T cells AIDS, 2019 Oct siRNA SR303243
YTHDC1 Epitranscriptomic addition of m 6 A regulates HIV-1 RNA stability and alternative splicing Genes & Development, 2021 Jul siRNA SR314128
YWHAB FAM163A, a positive regulator of ERK signaling pathway, interacts with 14-3-3β and promotes cell proliferation in squamous cell lung carcinoma Onco Targets Ther, 2019 Aug siRNA SR305137
YY1 Myocardial BDNF regulates cardiac bioenergetics through the transcription factor Yin Yang 1 bioRxiv, 2021 Jan siRNA SR501936
YY1 CLTRN, regulated by NRF1/RAN/DLD protein complex, enhances radiation sensitivity of hepatocellular carcinoma cells through ferroptosis pathway International journal of radiation oncology, biology, physics, 2021 Jan siRNA SR305136
YY1 Transcriptional regulation of human abraxas brother protein 1 expression by yin yang 1 Biochem. Cell Biol., 2020 Aug siRNA SR305136
ZBP1 ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling Bone Res, 2020 Mar siRNA SR413638